Structure and mechanism for streptococcal fatty acid kinase (Fak) system dedicated to host fatty acid scavenging

Domain architecture and catalysis of the Staphylococcus aureus fatty acid kinase

(2022) Chitra Subramanian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Enterococcus faecalis FabT Transcription Factor Regulates Fatty Acid Biosynthesis in Response to Exogeneous Fatty Acids

(2022) Qi Zou et al.   Frontiers in Microbiology

A type VII secretion system of Streptococcus gallolyticus subsp. gallolyticus contributes to gut colonization and the development of colon tumors

(2021) John Culver Taylor et al.   PLoS Pathogens

Staphylococcus aureus adapts to the host nutritional landscape to overcome tissue-specific branched-chain fatty acid requirement

(2021) Wei Ping Teoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemical and structural characterization of the BioZ enzyme engaged in bacterial biotin synthesis pathway

(2021) Sitao Zhang et al.   Nature Communications

The global emergence of a novel Streptococcus suis clade associated with human infections

(2021) Xingxing Dong et al.   EMBO Molecular Medicine

The poultry pathogen Riemerella anatipestifer appears as a reservoir for Tet(X) tigecycline resistance

(2021) Zeeshan Umar et al.   ENVIRONMENTAL MICROBIOLOGY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

To Make or Take: Bacterial Lipid Homeostasis during Infection

(2021) Felise G. Adams et al.   mBio

Host Fatty Acid Utilization by Staphylococcus aureus at the Infection Site

(2020) Matthew W. Frank et al.   mBio

Staphylococcus aureus Fatty Acid Kinase FakA Modulates Pathogenesis during Skin Infection via Proteases

(2020) Miranda J. Ridder et al.   INFECTION AND IMMUNITY

Genome Reduction Is Associated with Bacterial Pathogenicity across Different Scales of Temporal and Ecological Divergence

(2020) Gemma G R Murray et al.   MOLECULAR BIOLOGY AND EVOLUTION

Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli

(2019) Jian Sun et al.   Nature Microbiology

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

A fatty acid-binding protein of Streptococcus pneumoniae facilitates the acquisition of host polyunsaturated fatty acids

(2019) Jessica M. Gullett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Harnessing efficient multiplex PCR methods to detect the expanding Tet(X) family of tigecycline resistance genes

(2019) Kai Ji et al.   Virulence

Staphylococcus aureus Utilizes Host-Derived Lipoprotein Particles as Sources of Fatty Acids

(2018) Phillip C. Delekta et al.   JOURNAL OF BACTERIOLOGY

Acyl-chain selectivity and physiological roles of Staphylococcus aureus fatty acid–binding proteins

(2018) Maxime G. Cuypers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host-derived fatty acids activate type VII secretion inStaphylococcus aureus

(2017) Michael S. Lopez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical Streptococcus suis Virulence Factors: Are They All Really Critical?

(2017) Mariela Segura et al.   TRENDS IN MICROBIOLOGY

Streptococcus suis serotype 9 strain GZ0565 contains a type VII secretion system putative substrate EsxA that contributes to bacterial virulence and a vanZ- like gene that confers resistance to teicoplanin and dalbavancin in Streptococcus agalactiae

(2017) Liying Lai et al.   VETERINARY MICROBIOLOGY

Biochemical Roles for Conserved Residues in the Bacterial Fatty Acid-binding Protein Family

(2016) Tyler C. Broussard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dali server update

(2016) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Acetylation of Lysine 201 Inhibits the DNA-Binding Ability of PhoP to Regulate Salmonella Virulence

(2016) Jie Ren et al.   PLoS Pathogens

Activation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition inNeisseria

(2015) Jiangwei Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chlamydia trachomatisScavenges Host Fatty Acids for Phospholipid Synthesis via an Acyl-Acyl Carrier Protein Synthetase

(2015) Jiangwei Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How Bacterial Pathogens Eat Host Lipids: Implications for the Development of Fatty Acid Synthesis Therapeutics

(2015) Jiangwei Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach

(2015) Aurélien Chollet et al.   JOURNAL OF STRUCTURAL BIOLOGY

Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus

(2014) J. B. Parsons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Streptococcus suisinfection

(2014) Youjun Feng et al.   Virulence

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Phosphatidic acid synthesis in bacteria

(2012) Jiangwei Yao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A fine scale phenotype-genotype virulence map of a bacterial pathogen

(2012) T. van Opijnen et al.   GENOME RESEARCH

Proteome-wide protein interaction measurements of bacterial proteins of unknown function

(2012) M. Meier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural and mechanistic insight into covalent substrate binding by Escherichia coli dihydroxyacetone kinase

(2011) R. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors

(2011) J. B. Parsons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen

(2011) Claudio Palmieri et al.   Frontiers in Microbiology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Essentiality of FASII pathway for Staphylococcus aureus

(2010) Wendy Balemans et al.   NATURE

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Uncovering newly emerging variants of Streptococcus suis, an important zoonotic agent

(2010) Youjun Feng et al.   TRENDS IN MICROBIOLOGY

Expression ofVibrio harveyiAcyl-ACP Synthetase Allows Efficient Entry of Exogenous Fatty Acids into theEscherichia coliFatty Acid and Lipid A Synthetic Pathways

(2009) Yanfang Jiang et al.   BIOCHEMISTRY

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

(2009) Sophie Brinster et al.   NATURE