Quantum-Dot-Based Iron Oxide Nanoparticles Activate the NLRP3 Inflammasome in Murine Bone Marrow-Derived Dendritic Cells

Focus on the Role of the NLRP3 Inflammasome in Multiple Sclerosis: Pathogenesis, Diagnosis, and Therapeutics

(2022) Yueran Cui et al.   Frontiers in Molecular Neuroscience

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

(2021) Isak W. Tengesdal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Virus‐Spike Tumor‐Activatable Pyroptotic Agent

(2021) Sadia Nadeem et al.   Small

Imaging application and radiosensitivity enhancement of pectin decorated multifunctional magnetic nanoparticles in cancer therapy

(2021) Ankur Sood et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Alpha-ketoglutarate decorated iron oxide-gold core-shell nanoparticles for active mitochondrial targeting and radiosensitization enhancement in hepatocellular carcinoma

(2021) Ankur Sood et al.   Materials Science & Engineering C-Materials for Biological Applications

Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation involvement in low-dose CdTe QDs exposure-induced hepatotoxicity

(2021) Yanting Pang et al.   Redox Biology

Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation

(2020) Motao Zhu et al.   ACS Nano

In vitro and in vivo immunotoxicity of PEGylated Cd-free CuInS2/ZnS quantum dots

(2020) Tingting Chen et al.   Nanotoxicology

Toward targeting inflammasomes: insights into their regulation and activation

(2020) Shelbi Christgen et al.   CELL RESEARCH

A bioorthogonal system reveals antitumour immune function of pyroptosis

(2020) Qinyang Wang et al.   NATURE

Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer

(2020) Preethi Korangath et al.   Science Advances

Magnetic Nanohydrometallurgy Applied to Lanthanide Separation

(2020) Fernando de Melo et al.   Minerals

Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells

(2019) Ping-Hsien Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Magnetic behavior of superparamagnetic nanoparticles containing chelated transition metal ions

(2019) Fernando M. Melo et al.   JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

Engineered nano-immunopotentiators efficiently promote cancer immunotherapy for inhibiting and preventing lung metastasis of melanoma

(2019) Lijia Luo et al.   BIOMATERIALS

Size-dependent superparamagnetic iron oxide nanoparticles dictate interleukin-1β release from mouse bone marrow-derived macrophages

(2018) Shuzhen Chen et al.   JOURNAL OF APPLIED TOXICOLOGY

Impact of Morphology on Iron Oxide Nanoparticles-Induced Inflammasome Activation in Macrophages

(2018) Liu Liu et al.   ACS Applied Materials & Interfaces

SPIO Enhance the Cross-Presentation and Migration of DCs and Anionic SPIO Influence the Nanoadjuvant Effects Related to Interleukin-1β

(2018) Hui Liu et al.   Nanoscale Research Letters

The Effect of Superparamagnetic Iron Oxide Nanoparticle Surface Charge on Antigen Cross-Presentation

(2017) Yongbin Mou et al.   Nanoscale Research Letters

The Effect of Superparamagnetic Iron Oxide Nanoparticle Surface Charge on Antigen Cross-Presentation

(2017) Yongbin Mou et al.   Nanoscale Research Letters

Inflammasomes and Cancer

(2017) Rajendra Karki et al.   Cancer Immunology Research

Direct synthesis of magnetite nanoparticles from iron(II) carboxymethylcellulose and their performance as NMR contrast agents

(2016) Delmarcio Gomes da Silva et al.   JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

Cubic to tetragonal phase transition of Tm3+ doped nanocrystals in oxyfluoride glass ceramics

(2016) Yiming Li et al.   AIP Advances

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Necrotic cell death induced by the protein-mediated intercellular uptake of CdTe quantum dots

(2015) Lu Lai et al.   CHEMOSPHERE

Regulation of inflammasome activation

(2015) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Magnetic Nanoparticles in Cancer Theranostics

(2015) Oliviero L. Gobbo et al.   Theranostics

The induction of maturation on dendritic cells by TiO2 and Fe3O4@TiO2 nanoparticles via NF-κB signaling pathway

(2014) Rongrong Zhu et al.   Materials Science & Engineering C-Materials for Biological Applications

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC

(2013) V Sagulenko et al.   CELL DEATH AND DIFFERENTIATION

Inflammasome-derived IL-1β production induces nitric oxide–mediated resistance to Leishmania

(2013) Djalma S Lima-Junior et al.   NATURE MEDICINE

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Formation Pathways of Magnetite Nanoparticles by Coprecipitation Method

(2012) Taebin Ahn et al.   Journal of Physical Chemistry C

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

(2012) Geun-Shik Lee et al.   NATURE

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Cytotoxicity of InP/ZnS quantum dots related to reactive oxygen species generation

(2011) Hicham Chibli et al.   Nanoscale

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Folate conjugated carboxymethyl chitosan–manganese doped zinc sulphide nanoparticles for targeted drug delivery and imaging of cancer cells

(2009) Manjusha Elizabeth Mathew et al.   CARBOHYDRATE POLYMERS

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

(2009) Miyako Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Current status of cadmium as an environmental health problem

(2009) Lars Järup et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY