Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

(2018) Margherita Norelli et al.   NATURE MEDICINE

CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade

(2018) Theodoros Giavridis et al.   NATURE MEDICINE

Chimeric Antigen Receptor Therapy

(2018) Carl H. June et al.   NEW ENGLAND JOURNAL OF MEDICINE

CAR T cell immunotherapy for human cancer

(2018) Carl H. June et al.   SCIENCE

Endothelial-Specific Cre Mouse Models

(2018) Sophie Payne et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neutrophils in Homeostasis, Immunity, and Cancer

(2017) José Ángel Nicolás-Ávila et al.   IMMUNITY

Characterization of a conditional interleukin-1 receptor 1 mouse mutant using the Cre/LoxP system

(2016) Wesam H. Abdulaal et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophils in the Tumor Microenvironment

(2016) Davalyn R. Powell et al.   TRENDS IN IMMUNOLOGY

Redefining Myeloid Cell Subsets in Murine Spleen

(2016) Ying-Ying Hey et al.   Frontiers in Immunology

IL-1 Contributes to the Anti-Cancer Efficacy of Ingenol Mebutate

(2016) Thuy T. Le et al.   PLoS One

Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8+ T cells

(2015) Mark P. Rubinstein et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β

(2015) Jung-Eun Kim et al.   Theranostics

Tissue-Resident Memory T Cells

(2014) Jason M. Schenkel et al.   IMMUNITY

IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function

(2014) Jan P. Böttcher et al.   Cell Reports

The role IL-1 in tumor-mediated angiogenesis

(2014) Elena Voronov et al.   Frontiers in Physiology

IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R

(2013) C. E. Martin et al.   BLOOD

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells

(2013) Shlomo Z. Ben-Sasson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin 1 Enhances Vaccine-Induced Antifungal T-Helper 17 Cells and Resistance Against Blastomyces dermatitidis Infection

(2013) Marcel Wüthrich et al.   JOURNAL OF INFECTIOUS DISEASES

IL-12 selectively programs effector pathways that are stably expressed in human CD8+ effector memory T cells in vivo

(2011) F. Z. Chowdhury et al.   BLOOD

Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells

(2011) M. K. L. MacLeod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why not treat human cancer with interleukin-1 blockade?

(2010) Charles A. Dinarello   CANCER AND METASTASIS REVIEWS

Trans-presentation: A novel mechanism regulating IL-15 delivery and responses

(2009) Spencer W. Stonier et al.   IMMUNOLOGY LETTERS

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes

(2009) S. Yokoyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell