Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes

Cellular Function of TRIM E3 Ubiquitin Ligases in Health and Disease

(2022) Germana Meroni et al.   Cells

SAMHD1 … and Viral Ways around It

(2021) Janina Deutschmann et al.   Viruses-Basel

MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty

(2021) Chuanyin Li et al.   NUCLEIC ACIDS RESEARCH

Targeted Restriction of Viral Gene Expression and Replication by the ZAP Antiviral System

(2021) Mattia Ficarelli et al.   Annual Review of Virology

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

(2021) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry

(2021) Anh Phuong Luu et al.   Viruses-Basel

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

(2021) Thomas Kruse et al.   Nature Communications

PABPC4 Broadly Inhibits Coronavirus Replication by Degrading Nucleocapsid Protein through Selective Autophagy

(2021) Yajuan Jiao et al.   Microbiology Spectrum

Sensitivity of alphaviruses to G3BP deletion correlates with efficiency of replicase polyprotein processing

(2020) Benjamin Götte et al.   JOURNAL OF VIROLOGY

Structure-Mediated RNA Decay by UPF1 and G3BP1

(2020) Joseph W. Fischer et al.   MOLECULAR CELL

The Function of NM23-H1/NME1 and Its Homologs in Major Processes Linked to Metastasis

(2020) Barbara Mátyási et al.   PATHOLOGY & ONCOLOGY RESEARCH

TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway

(2020) Yanfeng Liu et al.   Nature Communications

Design and pharmaceutical applications of proteolysis-targeting chimeric molecules

(2020) Yuqing Liang et al.   BIOCHEMICAL PHARMACOLOGY

The antiviral activities of TRIM proteins

(2020) Lennart Koepke et al.   CURRENT OPINION IN MICROBIOLOGY

TRIM proteins

(2019) Milica Vunjak et al.   CURRENT BIOLOGY

UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond

(2019) Yoon Ki Kim et al.   RNA

hCLE/RTRAF-HSPC117-DDX1-FAM98B: A New Cap-Binding Complex That Activates mRNA Translation

(2019) Alejandra Pazo et al.   Frontiers in Physiology

System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection

(2019) Manuel Garcia-Moreno et al.   MOLECULAR CELL

An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis

(2019) Adarsh K. Mayank et al.   MOLECULAR CELL

Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

(2019) Benjamin Götte et al.   PLoS Pathogens

Interferon-Stimulated Genes: What Do They All Do?

(2019) John W. Schoggins   Annual Review of Virology

To TRIM or not to TRIM: the balance of host–virus interactions mediated by the ubiquitin system

(2019) Adam Hage et al.   JOURNAL OF GENERAL VIROLOGY

TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer

(2018) Ken-ichi Takayama et al.   ONCOGENE

The Enigmatic Alphavirus Non-Structural Protein 3 (nsP3) Revealing Its Secrets at Last

(2018) Benjamin Götte et al.   Viruses-Basel

Efp promotes in vitro and in vivo growth of endometrial cancer cells along with the activation of nuclear factor-κB signaling

(2018) Wataru Sato et al.   PLoS One

The ubiquitin ligase TRIM25 inhibits hepatocellular carcinoma progression by targeting metastasis associated 1 protein

(2017) Hong-liang Zang et al.   IUBMB LIFE

TRIM25 Is Required for the Antiviral Activity of Zinc Finger Antiviral Protein

(2017) Xiaojiao Zheng et al.   JOURNAL OF VIROLOGY

The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity

(2017) Qing Feng et al.   MOLECULAR CELL

TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis

(2017) Shigetsugu Hatakeyama   TRENDS IN BIOCHEMICAL SCIENCES

TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP)

(2017) Melody M. H. Li et al.   PLoS Pathogens

TRIM25 in the Regulation of the Antiviral Innate Immunity

(2017) María Martín-Vicente et al.   Frontiers in Immunology

The role of Trim25 in development, disease and RNA metabolism

(2016) G. Heikel et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity

(2016) Marios G Koliopoulos et al.   EMBO JOURNAL

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor

(2016) Adrien Decorsière et al.   NATURE

Isolation of ubiquitinated substrates by tandem affinity purification of E3 ligase–polyubiquitin-binding domain fusions (ligase traps)

(2016) Kevin G Mark et al.   Nature Protocols

CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering

(2016) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

ATP hydrolysis by UPF1 is required for efficient translation termination at premature stop codons

(2016) Lucas D. Serdar et al.   Nature Communications

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication

(2016) Tim Schulte et al.   Open Biology

New World and Old World Alphaviruses Have Evolved to Exploit Different Components of Stress Granules, FXR and G3BP Proteins, for Assembly of Viral Replication Complexes

(2016) Dal Young Kim et al.   PLoS Pathogens

Stress Granule Components G3BP1 and G3BP2 Play a Proviral Role Early in Chikungunya Virus Replication

(2015) Florine E. M. Scholte et al.   JOURNAL OF VIROLOGY

Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase Activity

(2015) Suzanne R. Lee et al.   MOLECULAR CELL

piggyBac-ing models and new therapeutic strategies

(2015) Lauren E. Woodard et al.   TRENDS IN BIOTECHNOLOGY

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

(2015) John L. Goodier et al.   PLoS Genetics

Viral and Cellular Proteins Containing FGDF Motifs Bind G3BP to Block Stress Granule Formation

(2015) Marc D. Panas et al.   PLoS Pathogens

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

The Host Nonsense-Mediated mRNA Decay Pathway Restricts Mammalian RNA Virus Replication

(2014) Giuseppe Balistreri et al.   Cell Host & Microbe

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

hCLE/C14orf166 Associates with DDX1-HSPC117-FAM98B in a Novel Transcription-Dependent Shuttling RNA-Transporting Complex

(2014) Alicia Pérez-González et al.   PLoS One

Poly(A) RNA-binding proteins and polyadenosine RNA: new members and novel functions

(2014) Callie P. Wigington et al.   Wiley Interdisciplinary Reviews-RNA

TRIMmunity: The Roles of the TRIM E3-Ubiquitin Ligase Family in Innate Antiviral Immunity

(2013) Ricardo Rajsbaum et al.   JOURNAL OF MOLECULAR BIOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Oestrogen causes ATBF1 protein degradation through the oestrogen-responsive E3 ubiquitin ligase EFP

(2012) Xue-Yuan Dong et al.   BIOCHEMICAL JOURNAL

HECT and RING finger families of E3 ubiquitin ligases at a glance

(2012) M. B. Metzger et al.   JOURNAL OF CELL SCIENCE

Attenuation of Chikungunya Virus Vaccine Strain 181/Clone 25 Is Determined by Two Amino Acid Substitutions in the E2 Envelope Glycoprotein

(2012) R. Gorchakov et al.   JOURNAL OF VIROLOGY

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs

(2011) H. M. Burgess et al.   JOURNAL OF CELL SCIENCE

Cellular Human CLE/C14orf166 Protein Interacts with Influenza Virus Polymerase and Is Required for Viral Replication

(2011) A. Rodriguez et al.   JOURNAL OF VIROLOGY

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus Replication

(2010) I. M. Cristea et al.   JOURNAL OF VIROLOGY

Interplay of Acute and Persistent Infections Caused by Venezuelan Equine Encephalitis Virus Encoding Mutated Capsid Protein

(2010) S. Atasheva et al.   JOURNAL OF VIROLOGY

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

(2010) Sumio Hayakawa et al.   NATURE IMMUNOLOGY

An Efficient and Reversible Transposable System for Gene Delivery and Lineage-Specific Differentiation in Human Embryonic Stem Cells

(2009) Arnaud Lacoste et al.   Cell Stem Cell

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

The SET Complex Acts as a Barrier to Autointegration of HIV-1

(2009) Nan Yan et al.   PLoS Pathogens

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

(2008) Wei Li et al.   PLoS One

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

(2008) M. Landthaler et al.   RNA