A synthetic ancestral kinesin-13 depolymerizes microtubules faster than any natural depolymerizing kinesin

The Mammalian Family of Katanin Microtubule-Severing Enzymes

(2021) Nicole A. Lynn et al.   Frontiers in Cell and Developmental Biology

Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate

(2018) Daria Trofimova et al.   Nature Communications

Parts list for a microtubule depolymerising kinesin

(2018) Claire T. Friel et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin

(2017) Weiyi Wang et al.   Nature Communications

Mechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation

(2017) Tadayuki Ogawa et al.   Cell Reports

The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition

(2016) Jennifer T. Patel et al.   Open Biology

Kinesins in cell migration

(2015) Alice Bachmann et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe

(2015) Anneke Hibbel et al.   eLife

The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch

(2015) Sandeep K Talapatra et al.   eLife

Prime movers: the mechanochemistry of mitotic kinesins

(2014) Robert A. Cross et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kinesin motors and primary cilia

(2012) Kristen J. Verhey et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment

(2012) Sarah B. Domnitz et al.   JOURNAL OF CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

FastML: a web server for probabilistic reconstruction of ancestral sequences

(2012) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Kinesin Assembly and Movement in Cells

(2011) Kristen J. Verhey et al.   Annual Review of Biophysics

The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization

(2011) Claire T Friel et al.   EMBO JOURNAL

Patterns of kinesin evolution reveal a complex ancestral eukaryote with a multifunctional cytoskeleton

(2010) Bill Wickstead et al.   BMC EVOLUTIONARY BIOLOGY

Key residues on microtubule responsible for activation of kinesin ATPase

(2010) Seiichi Uchimura et al.   EMBO JOURNAL

Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules

(2010) Stephanie C. Ems-McClung et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK

(2009) Jeremy R Cooper et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intraflagellar transport motors in cilia: moving along the cell's antenna

(2008) Jonathan M. Scholey   JOURNAL OF CELL BIOLOGY