Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics
出版年份 2019 全文链接
标题
Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics
作者
关键词
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出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 46, Pages 23124-23131
出版商
Proceedings of the National Academy of Sciences
发表日期
2019-10-29
DOI
10.1073/pnas.1904813116
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- (2018) Magnus Kjaergaard et al. ACS Chemical Neuroscience
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Sequence-to-Conformation Relationships of Disordered Regions Tethered to Folded Domains of Proteins
- (2018) Anuradha Mittal et al. JOURNAL OF MOLECULAR BIOLOGY
- Disordered linkers in mutli-domain allosteric proteins: entropic effect to favor the open state or enhanced local concentration to favor the closed state?
- (2018) Maodong Li et al. PROTEIN SCIENCE
- Extreme disorder in an ultrahigh-affinity protein complex
- (2018) Alessandro Borgia et al. NATURE
- Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs
- (2017) Yuan Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Decoupling of size and shape fluctuations in heteropolymeric sequences reconciles discrepancies in SAXS vs. FRET measurements
- (2017) Gustavo Fuertes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of transcriptional activity by design of charge patterning in the intrinsically disordered RAM region of the Notch receptor
- (2017) Kathryn P. Sherry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
- (2017) Joshua A. Riback et al. SCIENCE
- Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development
- (2017) Angela J Churchill et al. eLife
- Single-Molecule FRET Spectroscopy and the Polymer Physics of Unfolded and Intrinsically Disordered Proteins
- (2016) Benjamin Schuler et al. Annual Review of Biophysics
- The Role of Protein Loops and Linkers in Conformational Dynamics and Allostery
- (2016) Elena Papaleo et al. CHEMICAL REVIEWS
- Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation
- (2016) Erik W. Martin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cryptic sequence features within the disordered protein p27Kip1regulate cell cycle signaling
- (2016) Rahul K. Das et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Improving brightness and photostability of green and red fluorescent proteins for live cell imaging and FRET reporting
- (2016) Bryce T. Bajar et al. Scientific Reports
- Relating sequence encoded information to form and function of intrinsically disordered proteins
- (2015) Rahul K Das et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Effects of Linker Length and Transient Secondary Structure Elements in the Intrinsically Disordered Notch RAM Region on Notch Signaling
- (2015) Kathryn P. Sherry et al. JOURNAL OF MOLECULAR BIOLOGY
- Quantitative Assessments of the Distinct Contributions of Polypeptide Backbone Amides versus Side Chain Groups to Chain Expansion via Chemical Denaturation
- (2015) Alex S. Holehouse et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- Signalling scaffolds and local organization of cellular behaviour
- (2015) Lorene K. Langeberg et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering
- (2015) Giancarlo Tria et al. IUCrJ
- A broad view of scaffolding suggests that scaffolding proteins can actively control regulation and signaling of multienzyme complexes through allostery
- (2013) Ruth Nussinov et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Multisteric Regulation by Structural Disorder in Modular Signaling Proteins: An Extension of the Concept of Allostery
- (2013) Peter Tompa CHEMICAL REVIEWS
- Scaffold State Switching Amplifies, Accelerates, and Insulates Protein Kinase C Signaling
- (2013) Eric C. Greenwald et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
- (2013) R. K. Das et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model
- (2012) Takehisa Kitazawa et al. NATURE MEDICINE
- Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy
- (2012) H. Hofmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dependence of Avidity on Linker Length for a Bivalent Ligand–Bivalent Receptor Model System
- (2011) Eric T. Mack et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering
- (2011) Pau Bernadó et al. Molecular BioSystems
- p66 -MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex
- (2011) M. N. Gnanapragasam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information
- (2011) M. C. Good et al. SCIENCE
- Sequence Determinants of Compaction in Intrinsically Disordered Proteins
- (2010) Joseph A. Marsh et al. BIOPHYSICAL JOURNAL
- Net charge per residue modulates conformational ensembles of intrinsically disordered proteins
- (2010) A. H. Mao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Charge interactions can dominate the dimensions of intrinsically disordered proteins
- (2010) S. Muller-Spath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Statistical Mechanics of the Stability of Multivalent Ligand−Receptor Complexes
- (2009) D. J. Diestler et al. Journal of Physical Chemistry C
- Theory and simulations of charged polymers: From solution properties to polymeric nanomaterials
- (2008) A DOBRYNIN CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
- Statistical Thermodynamics of the Stability of Multivalent Ligand-Receptor Complexes
- (2008) D. J. Diestler et al. PHYSICAL REVIEW LETTERS
- Intrinsic disorder in scaffold proteins: Getting more from less
- (2008) Marc S. Cortese et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
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