Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons

Control of mammalian locomotion by ventral spinocerebellar tract neurons

(2022) Joshua I. Chalif et al.   CELL

Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain

(2022) Shannon Tansley et al.   Nature Communications

Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain

(2022) Samuel E. Marsh et al.   NATURE NEUROSCIENCE

ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

(2021) Jeffrey M. Granja et al.   NATURE GENETICS

Whole-brain tissue mapping toolkit using large-scale highly multiplexed immunofluorescence imaging and deep neural networks

(2021) Dragan Maric et al.   Nature Communications

Cerebellar contribution to sensorimotor adaptation deficits in humans with spinal cord injury

(2021) Yuming Lei et al.   Scientific Reports

A spinoparabrachial circuit defined by Tacr1 expression drives pain

(2021) Arnab Barik et al.   eLife

Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity

(2021) Shalaka Wahane et al.   Science Advances

Spinal cord injury alters spinal Shox2 interneurons by enhancing excitatory synaptic input and serotonergic modulation while maintaining intrinsic properties in mouse

(2021) D. Leonardo Garcia Ramirez et al.   JOURNAL OF NEUROSCIENCE

Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord

(2021) Mor R. Alkaslasi et al.   Nature Communications

Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord

(2021) Lindsay M. Milich et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spinal Cord Injury Induces Permanent Re-Programming of Microglia into a Disease-Associated State which Contributes to Functional Recovery

(2021) Ramil Hakim et al.   JOURNAL OF NEUROSCIENCE

Engineering spinal cord repair

(2021) Jordan W Squair et al.   CURRENT OPINION IN BIOTECHNOLOGY

scCODA is a Bayesian model for compositional single-cell data analysis

(2021) M. Büttner et al.   Nature Communications

A harmonized atlas of mouse spinal cord cell types and their spatial organization

(2021) Daniel E. Russ et al.   Nature Communications

Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation

(2020) Roberta Marisca et al.   NATURE NEUROSCIENCE

Divergent Neural Pathways Emanating from the Lateral Parabrachial Nucleus Mediate Distinct Components of the Pain Response

(2020) Michael C. Chiang et al.   NEURON

Cerebellospinal Neurons Regulate Motor Performance and Motor Learning

(2020) Anupama Sathyamurthy et al.   Cell Reports

MAGIC: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data

(2020) Avtar Roopra   PLoS Computational Biology

Protective Microglial Subset in Development, Aging, and Disease: Lessons From Transcriptomic Studies

(2020) Anouk Benmamar-Badel et al.   Frontiers in Immunology

Cell type prioritization in single-cell data

(2020) Michael A. Skinnider et al.   NATURE BIOTECHNOLOGY

Microglia-organized scar-free spinal cord repair in neonatal mice

(2020) Yi Li et al.   NATURE

Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury

(2020) William Renthal et al.   NEURON

Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans

(2020) Nicola Thrupp et al.   Cell Reports

Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury

(2020) Elisa M. Floriddia et al.   Nature Communications

The Success and Failure of the Schwann Cell Response to Nerve Injury

(2019) Kristjan R. Jessen et al.   Frontiers in Cellular Neuroscience

Molecular Logic of Spinocerebellar Tract Neuron Diversity and Connectivity

(2019) Myungin Baek et al.   Cell Reports

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

(2019) Christopher S. McGinnis et al.   Cell Systems

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Spinal cord repair: advances in biology and technology

(2019) Grégoire Courtine et al.   NATURE MEDICINE

Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors

(2019) Sumona P. Dhara et al.   Scientific Reports

Stereotyped transcriptomic transformation of somatosensory neurons in response to injury

(2019) Minh Q Nguyen et al.   eLife

Neuroinflammation after Traumatic Brain Injury Is Enhanced in Activating Transcription Factor 3 Mutant Mice

(2018) Philip Förstner et al.   JOURNAL OF NEUROTRAUMA

Dissecting spinal cord regeneration

(2018) Michael V. Sofroniew   NATURE

Cortico–reticulo–spinal circuit reorganization enables functional recovery after severe spinal cord contusion

(2018) Leonie Asboth et al.   NATURE NEUROSCIENCE

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

(2018) Martin Häring et al.   NATURE NEUROSCIENCE

The Biology of Regeneration Failure and Success After Spinal Cord Injury

(2018) Amanda Phuong Tran et al.   PHYSIOLOGICAL REVIEWS

Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior

(2018) Anupama Sathyamurthy et al.   Cell Reports

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia

(2018) Megan L. Gill et al.   NATURE MEDICINE

Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury

(2018) Claudia A. Angeli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Global Connectivity and Function of Descending Spinal Input Revealed by 3D Microscopy and Retrograde Transduction

(2018) Zimei Wang et al.   JOURNAL OF NEUROSCIENCE

Targeted neurotechnology restores walking in humans with spinal cord injury

(2018) Fabien B. Wagner et al.   NATURE

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

(2018) Qingyun Li et al.   NEURON

Single-nucleus and single-cell transcriptomes compared in matched cortical cell types

(2018) Trygve E. Bakken et al.   PLoS One

Spinal Shox2 interneuron interconnectivity related to function and development

(2018) Ngoc T Ha et al.   eLife

Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing

(2018) Kaya J.E. Matson et al.   Jove-Journal of Visualized Experiments

Cell biology of spinal cord injury and repair

(2017) Timothy M. O’Shea et al.   JOURNAL OF CLINICAL INVESTIGATION

Delineating the Diversity of Spinal Interneurons in Locomotor Circuits

(2017) Simon Gosgnach et al.   JOURNAL OF NEUROSCIENCE

Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury

(2017) Peggy Assinck et al.   JOURNAL OF NEUROSCIENCE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions

(2017) Yuanyuan Liu et al.   NEURON

Detecting Activated Cell Populations Using Single-Cell RNA-Seq

(2017) Ye Emily Wu et al.   NEURON

Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease

(2016) Willem Kamphuis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

(2016) S. Marques et al.   SCIENCE

Nuclear RNA-seq of single neurons reveals molecular signatures of activation

(2016) Benjamin Lacar et al.   Nature Communications

Overexpression of ATF3 or the combination of ATF3, c-Jun, STAT3 and Smad1 promotes regeneration of the central axon branch of sensory neurons but without synergistic effects

(2015) Nitish D. Fagoe et al.   HUMAN MOLECULAR GENETICS

Chronic Oligodendrogenesis and Remyelination after Spinal Cord Injury in Mice and Rats

(2015) Z. C. Hesp et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance

(2015) Linda Madisen et al.   NEURON

Restoration of skilled locomotion by sprouting corticospinal axons induced by co-deletion of PTEN and SOCS3

(2015) Duo Jin et al.   Nature Communications

What makes a RAG regeneration associated?

(2015) Thong C. Ma et al.   Frontiers in Molecular Neuroscience

Extrinsic and intrinsic regulation of axon regeneration at a crossroads

(2015) Andrew Kaplan et al.   Frontiers in Molecular Neuroscience

Spinal cord projections to the cerebellum in the mouse

(2014) Gulgun Sengul et al.   Brain Structure & Function

Sprouting of axonal collaterals after spinal cord injury is prevented by delayed axonal degeneration

(2014) E. Collyer et al.   EXPERIMENTAL NEUROLOGY

Locomotor Rhythm Generation Linked to the Output of Spinal Shox2 Excitatory Interneurons

(2013) Kimberly J. Dougherty et al.   NEURON

Vertebral landmarks for the identification of spinal cord segments in the mouse

(2012) Megan Harrison et al.   NEUROIMAGE

Motor Circuits in Action: Specification, Connectivity, and Function

(2012) Silvia Arber   NEURON

The transcription factor Sox11 promotes nerve regeneration through activation of the regeneration-associated gene Sprr1a

(2011) Xiaotang Jing et al.   EXPERIMENTAL NEUROLOGY

SPP1 expression in spinal motor neurons of the macaque monkey

(2010) Tatsuya Yamamoto et al.   NEUROSCIENCE RESEARCH

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Expression of the regeneration-associated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury

(2008) Michelle L. Starkey et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Prominent Role of the Spinal Central Pattern Generator in the Recovery of Locomotion after Partial Spinal Cord Injuries

(2008) G. Barriere et al.   JOURNAL OF NEUROSCIENCE

Axonal growth therapeutics: regeneration or sprouting or plasticity?

(2008) William B.J. Cafferty et al.   TRENDS IN NEUROSCIENCES

Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury

(2007) Gregoire Courtine et al.   NATURE MEDICINE