Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord

Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

(2020) Elke Ydens et al.   NATURE NEUROSCIENCE

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury

(2019) Victor Bellver-Landete et al.   Nature Communications

VEGF in Signaling and Disease: Beyond Discovery and Development

(2019) Rajendra S. Apte et al.   CELL

The origin, fate, and contribution of macrophages to spinal cord injury pathology

(2019) Lindsay M. Milich et al.   ACTA NEUROPATHOLOGICA

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

(2019) Hannah Van Hove et al.   NATURE NEUROSCIENCE

Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

(2019) Samuel L. Wolock et al.   Cell Systems

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Orchestrating single-cell analysis with Bioconductor

(2019) Robert A. Amezquita et al.   NATURE METHODS

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Single-cell profiling of the developing mouse brain and spinal cord with split-pool barcoding

(2018) Alexander B. Rosenberg et al.   SCIENCE

Apolipoprotein E Deficiency Exacerbates Spinal Cord Injury in Mice: Inflammatory Response and Oxidative Stress Mediated by NF-κB Signaling Pathway

(2018) Xuan Yang et al.   Frontiers in Cellular Neuroscience

Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior

(2018) Anupama Sathyamurthy et al.   Cell Reports

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Single-cell reconstruction of the early maternal–fetal interface in humans

(2018) Roser Vento-Tormo et al.   NATURE

Detecting Activated Cell Populations Using Single-Cell RNA-Seq

(2017) Ye Emily Wu et al.   NEURON

Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury

(2017) Yilong Ren et al.   Scientific Reports

Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems

(2016) L. Eklund et al.   CLINICAL SCIENCE

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury

(2016) Amber R. Hackett et al.   NEUROBIOLOGY OF DISEASE

Understanding the NG2 Glial Scar after Spinal Cord Injury

(2016) Amber R. Hackett et al.   Frontiers in Neurology

The role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders

(2015) Jian Guan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Astrocyte barriers to neurotoxic inflammation

(2015) Michael V. Sofroniew   NATURE REVIEWS NEUROSCIENCE

Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury

(2015) Y. Zhu et al.   NEUROBIOLOGY OF DISEASE

A draft network of ligand–receptor-mediated multicellular signalling in human

(2015) Jordan A. Ramilowski et al.   Nature Communications

Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding

(2014) R. B. Reinert et al.   DEVELOPMENT

Lymphocytes and autoimmunity after spinal cord injury

(2014) T. Bucky Jones   EXPERIMENTAL NEUROLOGY

Macrophages in spinal cord injury: Phenotypic and functional change from exposure to myelin debris

(2014) Xi Wang et al.   GLIA

ApoE mimetic ameliorates motor deficit and tissue damage in rat spinal cord injury

(2014) Ruihua Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

(2013) I. B. Wanner et al.   JOURNAL OF NEUROSCIENCE

Perivascular Fibroblasts Form the Fibrotic Scar after Contusive Spinal Cord Injury

(2013) C. Soderblom et al.   JOURNAL OF NEUROSCIENCE

RNA-Seq Characterization of Spinal Cord Injury Transcriptome in Acute/Subacute Phases: A Resource for Understanding the Pathology at the Systems Level

(2013) Kenian Chen et al.   PLoS One

Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment

(2010) Kevin D. Beck et al.   BRAIN

Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

(2010) Fanie Barnabé-Heider et al.   Cell Stem Cell

Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface

(2009) Hye Shin Lee et al.   FEBS Journal

Sonic Hedgehog Pathway Activation Is Induced by Acute Brain Injury and Regulated by Injury-Related Inflammation

(2009) N. M. Amankulor et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Cell-type-specific isolation of ribosome-associated mRNA from complex tissues

(2009) E. Sanz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The discovery of the placental growth factor and its role in angiogenesis: a historical review

(2008) Domenico Ribatti   ANGIOGENESIS

A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types

(2008) Myriam Heiman et al.   CELL

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE

Mechanisms and implications of adaptive immune responses after traumatic spinal cord injury

(2008) D.P. Ankeny et al.   NEUROSCIENCE