标题
Inflammasome signaling in colorectal cancer
作者
关键词
-
出版物
Translational Research
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2022-09-21
DOI
10.1016/j.trsl.2022.09.002
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The P2X7 Receptor Promotes Colorectal Inflammation and Tumorigenesis by Modulating Gut Microbiota and the Inflammasome
- (2022) Claudio Bernardazzi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pyroptosis is related to immune infiltration and predictive for survival of colon adenocarcinoma patients
- (2022) Huiwen Lu et al. Scientific Reports
- Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method
- (2022) Yaqiu Wang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- NLRP3 inflammasome in cancer and metabolic diseases
- (2021) Bhesh Raj Sharma et al. NATURE IMMUNOLOGY
- AIM2 Inhibits BRAF-Mutant Colorectal Cancer Growth in a Caspase-1-Dependent Manner
- (2021) Shailendra Shah et al. Frontiers in Cell and Developmental Biology
- AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence
- (2021) SangJoon Lee et al. NATURE
- ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
- (2021) Rajendra Karki et al. Cell Reports
- Dysregulated Microbiota-Driven Gasdermin D Activation Promotes Colitis Development by Mediating IL-18 Release
- (2021) Hanchao Gao et al. Frontiers in Immunology
- Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
- (2020) Min Zheng et al. CELL
- The Zα2 domain of ZBP1 is a molecular switch regulating influenza-induced PANoptosis and perinatal lethality during development
- (2020) Sannula Kesavardhana et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)
- (2020) Shelbi Christgen et al. Frontiers in Cellular and Infection Microbiology
- Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation
- (2020) Chunmei Ma et al. Science Advances
- Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection
- (2020) Min Zheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer
- (2020) Rajendra Karki et al. JCI Insight
- The tumor microenvironment
- (2020) Nicole M. Anderson et al. CURRENT BIOLOGY
- AIM2 inhibits colorectal cancer cell proliferation and migration through suppression of Gli1
- (2020) Menglin Xu et al. Aging-US
- Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
- (2020) Rajendra Karki et al. CELL
- ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis)
- (2020) Balaji Banoth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model
- (2019) Lieselot Croes et al. Cancers
- ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)
- (2019) R. K. Subbarao Malireddi et al. Frontiers in Cellular and Infection Microbiology
- Inflammasomes and the fine line between defense and disease
- (2019) Shelbi Christgen et al. CURRENT OPINION IN IMMUNOLOGY
- Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
- (2019) R.K. Subbarao Malireddi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis
- (2018) Deepika Sharma et al. GASTROENTEROLOGY
- TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
- (2018) R.K. Subbarao Malireddi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis
- (2018) Si Ming Man Nature Reviews Gastroenterology & Hepatology
- NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease
- (2018) Hazel Tye et al. Nature Communications
- Two variants of Interleukin-1B gene are associated with the decreased risk, clinical features, and better overall survival of colorectal cancer: a two-center case-control study
- (2018) Haihua Qian et al. Aging-US
- The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection
- (2018) Hideki Hara et al. CELL
- Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition
- (2017) Michail Mamantopoulos et al. IMMUNITY
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition
- (2017) Paul Lemire et al. Cell Reports
- Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation
- (2017) Adrian J. Błażejewski et al. Cell Reports
- Shaping of Intestinal Microbiota in Nlrp6- and Rag2-Deficient Mice Depends on Community Structure
- (2017) Eric J.C. Gálvez et al. Cell Reports
- Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome
- (2016) Qianming Du et al. BIOCHEMICAL PHARMACOLOGY
- The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway
- (2016) Rojo A Ratsimandresy et al. Cellular & Molecular Immunology
- NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer
- (2016) Rajendra Karki et al. NATURE
- NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis
- (2016) Prajwal Gurung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion
- (2016) G. M. H. Birchenough et al. SCIENCE
- Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling
- (2015) Maayan Levy et al. CELL
- Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer
- (2015) Si Ming Man et al. CELL
- Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
- (2015) Wan-ting He et al. CELL RESEARCH
- Regulation of inflammasome activation
- (2015) Si Ming Man et al. IMMUNOLOGICAL REVIEWS
- Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease
- (2015) Wiebe Vanhove et al. INFLAMMATORY BOWEL DISEASES
- Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin
- (2015) Jens Kortmann et al. JOURNAL OF IMMUNOLOGY
- The NLRP1 Inflammasome Attenuates Colitis and Colitis-Associated Tumorigenesis
- (2015) Tere M. Williams et al. JOURNAL OF IMMUNOLOGY
- Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt
- (2015) Justin E Wilson et al. NATURE MEDICINE
- Broad targeting of resistance to apoptosis in cancer
- (2015) Ramzi M. Mohammad et al. SEMINARS IN CANCER BIOLOGY
- Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components
- (2015) Rongrong Liu et al. Oncotarget
- Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer
- (2014) Wenjie Guo et al. Autophagy
- NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion
- (2014) Marta Wlodarska et al. CELL
- The complex role of inflammasomes in the pathogenesis of Inflammatory Bowel Diseases – Lessons learned from experimental models
- (2014) Mònica Aguilera et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients
- (2014) Susanne Dihlmann et al. INTERNATIONAL JOURNAL OF CANCER
- FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes
- (2014) P. Gurung et al. JOURNAL OF IMMUNOLOGY
- Dietary modulation of the microbiome affects autoinflammatory disease
- (2014) John R. Lukens et al. NATURE
- Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy
- (2014) J. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Colorectal cancer in inflammatory bowel disease: The risk, pathogenesis, prevention and diagnosis
- (2014) Eun Ran Kim WORLD JOURNAL OF GASTROENTEROLOGY
- Transcriptional analysis of the three Nlrp1 paralogs in mice
- (2013) Inka Sastalla et al. BMC GENOMICS
- Diet-Induced Obesity Promotes Colon Tumor Development in Azoxymethane-Treated Mice
- (2013) Iina Tuominen et al. PLoS One
- Genetic variation and alterations of genes involved in NFκB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer
- (2012) Jonas Ungerbäck et al. CARCINOGENESIS
- AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages
- (2012) R Pierini et al. CELL DEATH AND DIFFERENTIATION
- Incidence and Mortality of Colorectal Adenocarcinoma in Persons With Inflammatory Bowel Disease From 1998 to 2010
- (2012) Lisa J. Herrinton et al. GASTROENTEROLOGY
- Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges
- (2012) F A Carvalho et al. Mucosal Immunology
- IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
- (2012) Samuel Huber et al. NATURE
- Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infection
- (2012) Aaron W Puri et al. Nature Chemical Biology
- The Q705K Polymorphism in NLRP3 Is a Gain-of-Function Alteration Leading to Excessive Interleukin-1β and IL-18 Production
- (2012) Deepti Verma et al. PLoS One
- The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis
- (2011) Md. Hasan Zaki et al. CANCER CELL
- NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
- (2011) Eran Elinav et al. CELL
- A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis
- (2011) G. Y. Chen et al. JOURNAL OF IMMUNOLOGY
- The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
- (2011) Yue Zhao et al. NATURE
- Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
- (2011) S. Normand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
- (2010) Md. Hasan Zaki et al. IMMUNITY
- The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
- (2010) Irving C. Allen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Proteolytic Inactivation of Poly(ADP-Ribose) Polymerase 1 by the Nlrp3 and Nlrc4 Inflammasomes
- (2010) R. K. S. Malireddi et al. JOURNAL OF IMMUNOLOGY
- IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation
- (2010) M. H. Zaki et al. JOURNAL OF IMMUNOLOGY
- Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
- (2010) B. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
- Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes
- (2008) Mohamed Lamkanfi et al. MOLECULAR & CELLULAR PROTEOMICS
- Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
- (2008) Alexandra-Chloé Villani et al. NATURE GENETICS
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