Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans

Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet

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The Role of Gut Adaptation in the Potent Effects of Multiple Bariatric Surgeries on Obesity and Diabetes

(2015) Randy J. Seeley et al.   Cell Metabolism

MAFG Is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism

(2015) Thomas Q. de Aguiar Vallim et al.   Cell Metabolism

Dysfunctional Families: Clostridium scindens and Secondary Bile Acids Inhibit the Growth of Clostridium difficile

(2015) K. Leigh Greathouse et al.   Cell Metabolism

Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity

(2015) Michaela Mueller et al.   JOURNAL OF HEPATOLOGY

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(2015) Ryan D. Jones et al.   STEROIDS

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(2015) Changtao Jiang et al.   Nature Communications

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

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Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

(2014) Charlie G. Buffie et al.   NATURE

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applications

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Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

(2013) Fei Li et al.   Nature Communications

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Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line

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TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

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Regulation of Human CYP2C18 and CYP2C19 in Transgenic Mice: Influence of Castration, Testosterone, and Growth Hormone

(2009) S. Lofgren et al.   DRUG METABOLISM AND DISPOSITION

The enterohepatic circulation of bile acids in mammals: form and functions

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Identification of Human Hepatic Cytochrome P450 Enzymes Involved in the Biotransformation of Cholic and Chenodeoxycholic Acid

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Humanized Mouse Lines and Their Application for Prediction of Human Drug Metabolism and Toxicological Risk Assessment

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