CCL2 expression is mediated by type I IFN receptor and recruits NK and T cells to the lung during MVA infection

The mechanisms of genetically modified vaccinia viruses for the treatment of cancer

(2015) Artrish Jefferson et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Positive feedback regulation of type I interferon by the interferon-stimulated gene STING

(2015) F. Ma et al.   EMBO REPORTS

Alveolar macrophage–derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes

(2015) Michelle Goritzka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Natural Killer Cells and Innate Interferon Gamma Participate in the Host Defense against Respiratory Vaccinia Virus Infection

(2015) Georges Abboud et al.   JOURNAL OF VIROLOGY

NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses

(2015) Mauro Di Pilato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modified Vaccinia virus Ankara but not vaccinia virus induces chemokine expression in cells of the monocyte/macrophage lineage

(2015) Michael H Lehmann et al.   Virology Journal

Immune modulation by virus-encoded secreted chemokine binding proteins

(2015) Haleh Heidarieh et al.   VIRUS RESEARCH

Distinct Upstream Role of Type I IFN Signaling in Hematopoietic Stem Cell-Derived and Epithelial Resident Cells for Concerted Recruitment of Ly-6Chi Monocytes and NK Cells via CCL2-CCL3 Cascade

(2015) Erdenebileg Uyangaa et al.   PLoS Pathogens

Expression of CCL19 from Oncolytic Vaccinia Enhances Immunotherapeutic Potential while Maintaining Oncolytic Activity

(2015) Jun Li et al.   NEOPLASIA

Human cytomegalovirus replication supported by virus-induced activation of CCL2–CCR2 interactions

(2014) Tsugiya Murayama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Innate immune activation of NFκB and its antagonism by poxviruses

(2014) Gareth Brady et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Complement Component C5 Recruits Neutrophils in the Absence of C3 during Respiratory Infection with Modified Vaccinia Virus Ankara

(2014) Philip J. R. Price et al.   JOURNAL OF IMMUNOLOGY

CXCL12/CXCR4 Blockade by Oncolytic Virotherapy Inhibits Ovarian Cancer Growth by Decreasing Immunosuppression and Targeting Cancer-Initiating Cells

(2014) Margaret Gil et al.   JOURNAL OF IMMUNOLOGY

Differential Induction of Apoptosis, Interferon Signaling, and Phagocytosis in Macrophages Infected with a Panel of Attenuated and Nonattenuated Poxviruses

(2014) S. Royo et al.   JOURNAL OF VIROLOGY

Chemokine (C-C Motif) Receptor 1 Is Required for Efficient Recruitment of Neutrophils during Respiratory Infection with Modified Vaccinia Virus Ankara

(2014) P. J. R. Price et al.   JOURNAL OF VIROLOGY

Safety and immunogenicity of a modified-vaccinia-virus-Ankara-based influenza A H5N1 vaccine: a randomised, double-blind phase 1/2a clinical trial

(2014) Joost H C M Kreijtz et al.   LANCET INFECTIOUS DISEASES

Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway

(2014) Peihong Dai et al.   PLoS Pathogens

Oncolytic Poxviruses

(2014) Winnie M. Chan et al.   Annual Review of Virology

Clinical applications of attenuated MVA poxvirus strain

(2013) Carmen Elena Gómez et al.   Expert Review of Vaccines

IFNβ autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages

(2013) Michael J. Pattison et al.   FEBS LETTERS

Tumor associated macrophages and neutrophils in cancer

(2013) Maria Rosaria Galdiero et al.   IMMUNOBIOLOGY

Interferon induction and function at the mucosal surface

(2013) Russell K. Durbin et al.   IMMUNOLOGICAL REVIEWS

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity

(2013) G. L. Smith et al.   JOURNAL OF GENERAL VIROLOGY

Modified Vaccinia virus Ankara: Innate immune activation and induction of cellular signalling

(2013) Philip J.R. Price et al.   VACCINE

Interleukin-1β receptor expressed by modified vaccinia virus Ankara interferes with interleukin-1β activity produced in various virus-infected antigen-presenting cells

(2013) Stefan Zimmerling et al.   Virology Journal

Multifaceted Impact of Host C–C Chemokine CCL2 in the Immuno-Pathogenesis of HIV-1/M. tuberculosis Co-Infection

(2013) A. Wahid Ansari et al.   Frontiers in Immunology

Neutrophils Transport Antigen from the Dermis to the Bone Marrow, Initiating a Source of Memory CD8+ T Cells

(2012) Darragh Duffy et al.   IMMUNITY

Incorporation of the B18R Gene of Vaccinia Virus Into an Oncolytic Herpes Simplex Virus Improves Antitumor Activity

(2012) Xinping Fu et al.   MOLECULAR THERAPY

IFN-α-driven CCL2 production recruits inflammatory monocytes to infection site in mice

(2012) C D Conrady et al.   Mucosal Immunology

Astrocytic expression of HIV-1 Nef impairs spatial and recognition memory

(2012) Gladys Chompre et al.   NEUROBIOLOGY OF DISEASE

CCR2 Defines a Distinct Population of NK Cells and Mediates Their Migration during Influenza Virus Infection in Mice

(2012) Mary J. G. van Helden et al.   PLoS One

Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and Fc R signaling

(2012) C. D. Sadik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7

(2011) Leonie Unterholzner et al.   PLoS Pathogens

MCP-1: Chemoattractant with a role beyond immunity: A review

(2010) Amita Yadav et al.   CLINICA CHIMICA ACTA

Regulation of Inflammatory Monocyte/Macrophage Recruitment from the Bone Marrow during Murine Cytomegalovirus Infection: Role for Type I Interferons in Localized Induction of CCR2 Ligands

(2009) M. J. Crane et al.   JOURNAL OF IMMUNOLOGY

Modified Vaccinia Virus Ankara Triggers Chemotaxis of Monocytes and Early Respiratory Immigration of Leukocytes by Induction of CCL2 Expression

(2009) M. H. Lehmann et al.   JOURNAL OF VIROLOGY

Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands

(2009) Roman Barbalat et al.   NATURE IMMUNOLOGY

Modified vaccinia virus Ankara can activate NF-κB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication

(2009) Heather E. Lynch et al.   VIROLOGY

Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome

(2009) Julie Delaloye et al.   PLoS Pathogens

Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection

(2008) Christofer Samuelsson et al.   JOURNAL OF CLINICAL INVESTIGATION

Postexposure Immunization with Modified Vaccinia Virus Ankara or Conventional Lister Vaccine Provides Solid Protection in a Murine Model of Human Smallpox

(2008) Nir Paran et al.   JOURNAL OF INFECTIOUS DISEASES

Respiratory Syncytial Virus Activates Innate Immunity through Toll-Like Receptor 2

(2008) M. R. Murawski et al.   JOURNAL OF VIROLOGY