标题
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
作者
关键词
-
出版物
NEW ENGLAND JOURNAL OF MEDICINE
Volume 387, Issue 12, Pages 1099-1110
出版商
Massachusetts Medical Society
发表日期
2022-09-22
DOI
10.1056/nejmoa2204705
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Design of a Randomized, Placebo-Controlled, Phase 3 Trial of Tofersen Initiated in Clinically Presymptomatic SOD1 Variant Carriers: the ATLAS Study
- (2022) Michael Benatar et al. Neurotherapeutics
- Diagnostic-prognostic value and electrophysiological correlates of CSF biomarkers of neurodegeneration and neuroinflammation in amyotrophic lateral sclerosis
- (2020) Samir Abu-Rumeileh et al. JOURNAL OF NEUROLOGY
- Neurofilament light chain and C reactive protein explored as predictors of survival in amyotrophic lateral sclerosis
- (2020) Maxim De Schaepdryver et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Validation of serum neurofilaments as prognostic and potential pharmacodynamic biomarkers for ALS
- (2020) Michael Benatar et al. NEUROLOGY
- Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
- (2020) Timothy Miller et al. NEW ENGLAND JOURNAL OF MEDICINE
- Diagnostic and Prognostic Performance of Neurofilaments in ALS
- (2019) Koen Poesen et al. Frontiers in Neurology
- Structural Properties and Interaction Partners of Familial ALS-Associated SOD1 Mutants
- (2019) Jisen Huai et al. Frontiers in Neurology
- Effect of High‐Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis
- (2019) Albert C. Ludolph et al. ANNALS OF NEUROLOGY
- Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models
- (2018) Alex McCampbell et al. JOURNAL OF CLINICAL INVESTIGATION
- Comprehensive analysis of the mutation spectrum in 301 German ALS families
- (2018) Kathrin Müller et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial
- (2018) Albert C Ludolph et al. LANCET NEUROLOGY
- Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressiveSOD1ALS
- (2018) Michael Benatar et al. NEUROLOGY
- Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis
- (2018) Elaheh Ekhtiari Bidhendi et al. ACTA NEUROPATHOLOGICA
- Neurofilament light chain in serum for the diagnosis of amyotrophic lateral sclerosis
- (2018) Federico Verde et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Antisense oligonucleotides: the next frontier for treatment of neurological disorders
- (2017) Carlo Rinaldi et al. Nature Reviews Neurology
- Increase in DNA methylation in patients with amyotrophic lateral sclerosis carriers of not fully penetrant SOD1 mutations
- (2017) Fabio Coppedè et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis
- (2017) Alessandra Gaiani et al. JAMA Neurology
- Defining SOD1 ALS natural history to guide therapeutic clinical trial design
- (2016) Taha Bali et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis
- (2015) C.-H. Lu et al. NEUROLOGY
- SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology
- (2014) Rosie K. A. Bunton-Stasyshyn et al. NEUROSCIENTIST
- Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
- (2013) Rachele A. Saccon et al. BRAIN
- Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
- (2009) Hristelina Ilieva et al. JOURNAL OF CELL BIOLOGY
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