Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis

Spinal cord homogenates from SOD1 familial amyotrophic lateral sclerosis induce SOD1 aggregation in living cells

(2017) Edward Pokrishevsky et al.   PLoS One

Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS

(2016) Jacob I. Ayers et al.   ACTA NEUROPATHOLOGICA

Two superoxide dismutase prion strains transmit amyotrophic lateral sclerosis–like disease

(2016) Elaheh Ekhtiari Bidhendi et al.   JOURNAL OF CLINICAL INVESTIGATION

Mammalian prions and their wider relevance in neurodegenerative diseases

(2016) John Collinge   NATURE

Age-related myelin degradation burdens the clearance function of microglia during aging

(2016) Shima Safaiyan et al.   NATURE NEUROSCIENCE

A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration

(2016) Dominic M. Walsh et al.   NATURE REVIEWS NEUROSCIENCE

Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase

(2016) Eiichi Tokuda et al.   Acta Neuropathologica Communications

Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways

(2015) Jacob I. Ayers et al.   ACTA NEUROPATHOLOGICA

Structural and kinetic analysis of protein-aggregate strains in vivo using binary epitope mapping

(2015) Johan Bergh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental transmissibility of mutant SOD1 motor neuron disease

(2014) Jacob I. Ayers et al.   ACTA NEUROPATHOLOGICA

Rodent models of amyotrophic lateral sclerosis

(2013) Philip McGoldrick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Expression of wild-type human superoxide dismutase-1 in mice causes amyotrophic lateral sclerosis

(2012) K. S. Graffmo et al.   HUMAN MOLECULAR GENETICS

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

(2012) Kelvin C. Luk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Composition of Soluble Misfolded Superoxide Dismutase-1 in Murine Models of Amyotrophic Lateral Sclerosis

(2012) Per Zetterström et al.   NEUROMOLECULAR MEDICINE

Fibrillation precursor of superoxide dismutase 1 revealed by gradual tuning of the protein-folding equilibrium

(2012) L. Lang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis

(2011) Karin Forsberg et al.   ACTA NEUROPATHOLOGICA

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

(2011) Peter M. Andersen et al.   Nature Reviews Neurology

Prion-like acceleration of a synucleinopathy in a transgenic mouse model

(2011) Anne-Laure Mougenot et al.   NEUROBIOLOGY OF AGING

Prions

(2011) D. W. Colby et al.   Cold Spring Harbor Perspectives in Biology

Novel Antibodies Reveal Inclusions Containing Non-Native SOD1 in Sporadic ALS Patients

(2010) Karin Forsberg et al.   PLoS One

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Superoxide dismutase in amyotrophic lateral sclerosis patients homozygous for the D90A mutation

(2009) P. Andreas Jonsson et al.   NEUROBIOLOGY OF DISEASE

ALSOD: The Amyotrophic Lateral Sclerosis Online Database

(2008) Richard Wroe et al.   Amyotrophic Lateral Sclerosis

Inclusions of amyotrophic lateral sclerosis-linked superoxide dismutase in ventral horns, liver, and kidney

(2008) P. Andreas Jonsson et al.   ANNALS OF NEUROLOGY

Complete Loss of Post-translational Modifications Triggers Fibrillar Aggregation of SOD1 in the Familial Form of Amyotrophic Lateral Sclerosis

(2008) Yoshiaki Furukawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Initiation and elongation in fibrillation of ALS-linked superoxide dismutase

(2008) M. Chattopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA