Article
Chemistry, Physical
Xiaowu Wang, Jiwen Hui, Minmin Shi, Xinhui Kou, Xiaoxiao Li, Ronglin Zhong, Zhibo Li
Summary: In this study, a one-component Lewis pair strategy was adopted to achieve living propylene oxide polymerization and prepare high-molecular-weight polypropylene oxide. The success of this strategy is attributed to better control and rapid polymerization kinetics, utilizing the unique structures and synergistic effect of the Lewis pairs. Spectroscopic data analysis and density functional theory calculations provided insightful mechanistic understanding of this designed Lewis pair system.
Article
Polymer Science
Yongzhuang Du, Xiaoqiang Xue, Qimin Jiang, Wenyan Huang, Hongjun Yang, Li Jiang, Bibiao Jiang, Sridhar Komarneni
Summary: This study investigated the ring-opening mechanism of epoxides in the presence of tertiary amines. Gas chromatography (GC) and size-exclusion chromatography (SEC) were used to analyze monomer conversion and molecular weights of the polymers. Nuclear magnetic resonance (NMR) spectroscopy was employed to examine polymer structures. The results showed that the ring-opening reaction only occurred when tertiary amines and hydroxyl-containing compounds were present together, indicating an interaction between tertiary amines and hydroxyl groups. The mechanisms of ring-opening reactions catalyzed by tertiary amines varied depending on the structures of the epoxides.
Article
Chemistry, Applied
Michael Lalanne-Tisne, Samuel Eyley, Julien De Winter, Audrey Favrelle-Huret, Wim Thielemans, Philippe Zinck
Summary: This study investigates the surface modification of cellulose nanocrystals through organocatalysed ring-opening polymerization of trimethylene carbonate. The researchers successfully assessed different organocatalysts and found that the grafting ratio can be controlled by adjusting the experimental parameters. Additionally, the modified material exhibits polymeric behavior, indicating a sufficient graft length.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Applied
Chinh Hoang Tran, Linh Thi Thuy Pham, Han Byeol Jang, Sun A. Kim, Il Kim
Summary: Using dicarbonyl compounds as complexing agents for Zn(II)-Co(III) DMC catalysts in the ring-opening polymerization of epoxides can lead to higher yields and lower unsaturation levels in the resulting polyols. The ability to tune the catalytic behavior with these new complexing agents offers great potential for the synthesis of high quality polyols.
Article
Polymer Science
Huan Qi, Rui Xie, Guan-Wen Yang, Yao-Yao Zhang, Cheng-Kai Xu, Yuhui Wang, Guang-Peng Wu
Summary: This study systematically investigates the catalytic performance of a series of well-defined organoboron catalysts in ring-opening polymerization (ROP) of epoxides. It is found that the increase of Lewis acidity and the number of B centers of the catalysts contribute to a high catalytic activity. Additionally, the catalysts are capable of producing telechelic polyols with controllable molecular weight in the presence of different chain transfer agents.
Article
Chemistry, Applied
Linlin Zhu, Qinyong Chen, Ying Wang, Huishan Huang, Wenyi Luo, Zhunxuan Li, Zhen Zhang, Nikos Hadjichristidis
Summary: A facile and effective method involving ring-opening copolymerization of N-sulfonyl aziridines towards cellulose has been developed for efficient oil/water separation. The modified cellulose paper material showed promising properties for efficient oil/water separations, with a grafting ratio ranging from 96 to 150% and a contact angle over 127°.
CARBOHYDRATE POLYMERS
(2021)
Article
Polymer Science
Chunwei Zhuo, Han Cao, Huai You, Shunjie Liu, Xianhong Wang, Fosong Wang
Summary: A photothermal strategy was developed using visible light as an external stimulus for the copolymerization of carbon dioxide and epoxides. This strategy showed enhanced polymerization activity and demonstrated spatial-temporal control.
Article
Polymer Science
Chao Chen, Yves Gnanou, Xiaoshuang Feng
Summary: In this study, a series of bifunctional borinane-based catalysts were successfully designed and synthesized for efficient ring-opening polymerization of epoxides under mild conditions, resulting in high molar mass polyethers. These catalysts showed high productivity even at low loading amounts, as low as 50 ppb, when used with chain transfer agents. Additionally, they demonstrated record turnover frequency (TOF) values and molar masses for the polymerization of oxetane.
Article
Chemistry, Multidisciplinary
Ying Quan, Cuihong Ma, Qiancai Liu, Zhiying Han, Huijing Han, Xiaojuan Liao, Ruyi Sun, Meiran Xie
Summary: In this study, a novel cascade O-S ER/AAROP method was developed to obtain a well-defined hydroxyl-containing linear polythioether. The reaction mechanism was revealed by real-time monitoring, and the use of organic ammonium salt significantly improved the yield and molecular weight of the polythioether. This work presents a green strategy for the direct synthesis of linear poly(hydroxyl thioether)s from epoxides under mild conditions.
Article
Polymer Science
Arianna Brandolese, Francesco Della Monica, Miquel A. Pericas, Arjan W. Kleij
Summary: In this study, a new catalytic process was developed to efficiently synthesize functional polyesters. The degree of functionalization and the nature of the polymer backbone were controlled by monomer design. Furthermore, postpolymerization cross-linking processes were investigated to create materials with switchable thermal and mechanical properties through the construction of rigid macromolecular networks.
Article
Polymer Science
Xiaowu Wang, Minmin Shi, Jiwen Hui, Xinhui Kou, Jiansen Wang, Ronglin Zhong, Zhibo Li
Summary: A metal-free phosphonium bisborane Lewis pair (PBB-Br) was used as a catalyst for the immortal ring-opening polymerization (iROP) of propylene oxide (PO) with alcohols as chain-transfer agents (CTAs). Narrow dispersed poly-(propylene oxides)(PPOs) with controllable molecular weights were obtained. The iROP feature of PBB-Br-catalyzed PO polymerization was demonstrated, allowing for the production of various well-defined heterofunctionalized PPOs.
Article
Polymer Science
Kai-Xuan Qin, Shi-Si Li, Jing Xu, Zi-Long Li, Zi-Chen Li, Chunzu Cheng
Summary: In this study, amorphous aliphatic polyesters were successfully synthesized via organocatalyzed ring-opening polymerization. The monomer of the polyester is a novel downstream product of non-edible citronella oil. The chemical transformation of the alkene moiety owned by the renewable biomass was achieved through cross-metathesis with methyl acrylate. The three-armed star polymers were converted into free-standing films by UV-induced crosslinking, and these crosslinked thin films could be efficiently recycled as omega-hydroxy ester through methanolysis. This work opens a new avenue for the synthesis and application of terpene- and terpenoid-based polymers.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Tianle Gao, Xiaochao Xia, Kenji Tajima, Takuya Yamamoto, Takuya Isono, Toshifumi Satoh
Summary: Alkali metal carboxylates have been identified as effective catalysts for the ring-opening polymerization of various epoxides and episulfides, resulting in the production of functional polyethers and polythioethers with well-defined structures and controlled molecular weights. By tuning the acid/base characteristics through variations in carboxylate moieties and alkali metal cations, the polymerization behavior can be controlled and the scope of functional monomers and initiators expanded.
Article
Polymer Science
Tianle Gao, Xiaochao Xia, Kenji Tajima, Takuya Yamamoto, Takuya Isono, Toshifumi Satoh
Summary: Alkali metal carboxylates can serve as simple and green catalysts for the ring-opening polymerization of epoxides and episulfides, enabling the production of functional polyethers and polythioethers with well-defined structures and controlled molecular weights.
Article
Chemistry, Applied
Debao Mu, Chunping Feng, Wenyi Li, Dan Yuan, Yingming Yao
Summary: Four aluminum, zinc, and aluminum/zinc heterometallic complexes stabilized by o-phenylenediamine bridged poly (phenolato) ligands were synthesized and investigated for their catalytic behavior in the ring-opening polymerization of cyclohexene oxide. Heterometallic complex 4 showed significantly enhanced activity.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)