Article
Biochemistry & Molecular Biology
Bruno Las-Casas, Isabella K. R. Dias, Sergio Luis Yupanqui-Mendoza, Barbara Pereira, Guilherme R. Costa, Orlando J. Rojas, Valdeir Arantes
Summary: This article summarizes the unique properties and environmental benefits of cellulose nanomaterials (CNs), with a focus on cellulose nanofibrils (CNFs) and nanocrystals (CNCs), which are the most extensively researched types of CNs. The authors propose hybrid cellulose nanomaterials (HCNs) as the standardized classification for these materials and comprehensively examine their potential and performance in various applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Yening Xia, Georg M. Scheutz, Charles P. Easterling, Junpeng Zhao, Brent S. Sumerlin
Summary: This study introduces a method for synthesizing well-defined polyacrylamido-b-polyether block copolymers by combining photoiniferter polymerization and organocatalytic ring-opening polymerization. The compatibility between the two polymerization systems is demonstrated, allowing for the tailored synthesis of block copolymers from chemically distinct monomers.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Materials Science, Multidisciplinary
Siping Hu, Jianxu Chen, Xun Zhang, Yuying Zhang, Saihu Liao
Summary: Visible light-regulated organocatalytic polymerization has received significant attention in recent years due to its mild, metal-free reaction conditions and the ability to mediate polymerization with spatial and temporal control. In this study, hydroxybenzophenones (BPOHs) were successfully identified as an effective class of photoacid catalysts for the ring-opening polymerization of lactones, resulting in biodegradable polyester products with predictable molecular mass and low dispersity under visible light irradiation.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Polymer Science
Yuejia Zhu, Yongzhu Hu, Zhenjiang Li, Bo Liu, Yuanyuan Qu, Zhihao Zhang, Tianfo Guo, Yongqiang Li, Luoyu Gao, Kai Guo
Summary: By introducing 3-amino-1,2,4-benzo-thiadiazine-1,1-dioxide (ABTD) as a bidentate H-bond donor and triethylamine (TEA) as a mild Lewis base, successful control of polylactide (PLA) with predictable molecular weights and extremely narrow dispersities was achieved in room temperature solutions.
EUROPEAN POLYMER JOURNAL
(2021)
Review
Chemistry, Multidisciplinary
Katja Heise, Eero Kontturi, Yagut Allahverdiyeva, Tekla Tammelin, Markus B. Linder, Nonappa, Olli Ikkala
Summary: Nanocelluloses have attracted significant attention in the pursuit of sustainable advanced functional materials. Despite facing challenges in mastering their interactions and tailorability, recent progress in water interactions and advanced hybrid gels has opened up new directions for potential applications like nanocomposites, gels, and composite fibers.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Jiandong Li, Fusheng Liu, Yalei Liu, Yong Shen, Zhibo Li
Summary: This study presents a method for chemoselective controlled ring-opening polymerization of bio-renewable bifunctional alpha-methylene-delta-valerolactone (MVL) using strong base/urea binary catalysts. The obtained high molecular weight polyester exhibits good mechanical properties. The pristine monomer can be recovered through thermolysis, establishing a closed-loop life cycle.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Review
Chemistry, Multidisciplinary
Xiaoqian Wang, Ziyu Huo, Xiaoyu Xie, Narasimhamurthy Shanaiah, Rong Tong
Summary: The demand to replace unsustainable polyolefins drives the transformation of renewable resources into functional and degradable polymers. However, the properties of many degradable homopolymers are inferior to commodity polyolefins, limiting their utility. One-pot synthesis of sequence-defined copolymers from cyclic monomer mixtures is attractive in terms of concept and economics, as it maximizes materials usage and improves polymer performance. Recent advances in one-pot, sequence-controlled polymerizations of cyclic monomer mixtures using a single catalytic system that combines multiple catalytic cycles are highlighted, including the scopes of cyclic monomers, catalysts, and polymerization mechanisms.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Review
Polymer Science
Abd Ghafar Nurhanis Sofiah, Jagadeesh Pasupuleti, Mahendran Samykano, Kumaran Kadirgama, Siaw Paw Koh, Sieh Kieh Tiong, Adarsh Kumar Pandey, Chong Tak Yaw, Sendhil Kumar Natarajan
Summary: This article provides a comprehensive overview of nanocellulose preparation methods, structure-property correlations, and applications. Nanocellulose is a renewable and sustainable material with tunable surface properties and biocompatibility. The article discusses the classification and production methods of nanocellulose, highlights its unique properties derived from experiments and studies, and elaborates on its potential applications in various areas.
Review
Chemistry, Applied
Qianqian Wang, Simeng Liu, Jun Liu, Jianzhong Sun, Zhen Zhang, Qianqian Zhu
Summary: CNMs membranes, as a novel membrane material based on green resources and sustainable processes, have great potential in environmental remediation. Understanding the interactions between CNMs and different substances, as well as their selective transport mechanisms in membrane separation processes, is crucial for their practical applications.
CARBOHYDRATE POLYMERS
(2022)
Review
Polymer Science
Mehran Ghasemlou, Fugen Daver, Elena P. Ivanova, Youssef Habibi, Benu Adhikari
Summary: Nanocellulose is a highly promising material with abundant and renewable sources, biocompatibility, nanoscale dimension, high specific surface area, and tunable surface chemistry. However, its hydrophilicity presents challenges for its dispersion in hydrophobic host polymers. Manipulation of nanocellulose's interfacial properties is crucial for its successful application in new materials development.
PROGRESS IN POLYMER SCIENCE
(2021)
Review
Nanoscience & Nanotechnology
Wei Liu, Kun Liu, Haishun Du, Ting Zheng, Ning Zhang, Ting Xu, Bo Pang, Xinyu Zhang, Chuanling Si, Kai Zhang
Summary: This article summarizes and discusses the recent progress in the fabrication and applications of cellulose nanopaper, including the characteristics of various types of nanocellulose, preparation methods, and their applications in different fields.
NANO-MICRO LETTERS
(2022)
Review
Environmental Sciences
Mehmet Emin Pasaoglu, Ismail Koyuncu
Summary: Engineered composites commonly use fibrous reinforcing materials such as carbon fiber and glass fiber, but there is growing interest in biobased materials like plant fibers. Nanocelluloses, projected to be cheaper and potentially produce in great quantities, have garnered particular interest recently.
Article
Materials Science, Composites
Thi Vi Vi Do, Ngoc Bao An Tran, Ngoc Uyen Nguyen-Thai
Summary: This study extracted spherical cellulose nanocrystals from Gai bamboo fibers through sulfuric acid hydrolysis methods. The changes in bond's vibration and thermogravimetric diagram indicated the removal of amorphous components, lignin, and hemicellulose in the raw bamboo fiber and the incorporation of sulfate groups. The nanocellulose exhibited a spherical shape with a diameter of 2 to 10 nm, a crystallization index of 70.30%, and a crystallization degree of 0.77. The chitosan films loaded with spherical nanocellulose showed improved thermal and mechanical properties, including increased tensile strength, modulus, elongation at break, and decreased moisture absorption.
POLYMER COMPOSITES
(2023)
Article
Chemistry, Applied
Stephan Schandl, Thomas Koch, Juergen Stampfl, Katharina Ehrmann, Robert Liska
Summary: Aliphatic polycarbonates are highly regarded for being sustainable, biodegradable, and biocompatible. Recently, photobase generators have made cyclic carbonates available for light-induced anionic ring-opening polymerization, leading to the formation of pure aliphatic polycarbonate networks. The polymerization mechanism was investigated using photo-DSC and photorheology on synthesized cyclic carbonates. Different ratios of reactive diluent to crosslinker were tested to obtain materials with tunable mechanical properties.
REACTIVE & FUNCTIONAL POLYMERS
(2023)
Review
Biochemistry & Molecular Biology
Rekha Goswami, Simranjeet Singh, Pavithra Narasimhappa, Praveen C. Ramamurthy, Abhilasha Mishra, Pawan Kumar Mishra, Harish Chandra Joshi, Gaurav Pant, Joginder Singh, Gaurav Kumar, Nadeem A. Khan, Mahmood Yousefi
Summary: This review discusses the application of nanocellulose materials in water remediation. Nanocellulose materials are characterized by their lightweight, cost-effectiveness, mechanical strength, and easy availability, making them suitable for removing various pollutants.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Polymer Science
Ruth Cardinaels, An-Sofie Huysecom, Wim Thielemans, Paula Moldenaers
Summary: In this study, we investigate the temporary network topology and elasticity of micellar networks formed by hydrophobically associating multiblock copolymers. By using a combinatorics approach, we extend the mechano-statistical transient network model to multiblock copolymers and show that the micellar network microstructure can predict the concentration dependent elasticity. The network transitions from loop-dominated, poorly elastic structures with low functional cross-linking nodes at low concentrations to bridge-dominated, highly elastic structures with higher functional nodes at elevated concentrations.
Article
Chemistry, Applied
Zuxin Sun, Wim Thielemans
Summary: In this study, the cycling stability and capacitance performance of polypyrrole (PPy) electrode material were improved by doping with carboxylated cellulose nanocrystals (CNC-COO-) and commonly used salts. The results showed that the porous structure formed by doping enhanced the energy storage capacity and charging rate of the PPy-based films.
JOURNAL OF ENERGY CHEMISTRY
(2023)
Article
Pharmacology & Pharmacy
Maarten A. Mees, Fleur Boone, Thomas Bouwen, Frederik Vanaerschot, Charlotte Titeca, Hanna-Kaisa Vikkula, Leen Catrysse, Anja Vananroye, Erin Koos, Stelios Alexandris, Sabine Rosenfeldt, Samuel Eyley, Joachim Koetz, Geert van Loo, Wim Thielemans, Esther Hoste
Summary: High-mobility group box 1 (HMGB1) released during wounding delays skin regeneration. We discovered that dissolving glycyrrhizin in water forms a hydrogel with remarkable rheological properties. Glycyrrhizin-based hydrogels accelerate the closure of cutaneous wounds in normoglycemic and diabetic mice by influencing keratinocyte migration.
Article
Engineering, Environmental
Hongshan Zhu, Stephan Heinitz, Samuel Eyley, Wim Thielemans, Koen Binnemans, Steven Mullens, Thomas Cardinaels
Summary: 213Bi-labeled radiopharmaceuticals for cancer treatment are of great interest, and finding a suitable sorbent material for separating 213Bi from its parent radionuclide 225Ac is challenging. This study reports on the synthesis and evaluation of sulfonated carbon materials (SCMs) as sorbents in inverse 225Ac/213Bi generators. The sulfonation of carbon materials prepared at 500 degrees C (SCM-500) showed promising results, with high selectivity for Bi3+ over La3+ and high chemical 213Bi yield in column tests.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Pengtao Gao, Jianjun Huang, Efecan Pakkaner, Jeroen Wagemans, Samuel Eyley, Wim Thielemans, Rik Gijsbers, Mario Smet, Xing Yang
Summary: In this study, a new class of pH-responsive PVDF-g-PDMAEMA membranes was synthesized using a one-pot synthesis strategy. The membranes demonstrated competitive water permeance and binding capacity, and maintained robust performance after multiple operation cycles.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Fanglei Guo, Wei Yu, Olivier Deschaume, Stijn Jooken, Liwang Liu, Qi Wei, Wim Thielemans, Carmen Bartic
Summary: In this study, a nanoparticle-based, light-controlled platform was developed to modulate the beating rate of cardiomyocytes. The platform utilized near-infrared stimulation and quantum dot thermometry for local temperature monitoring. This method is highly valuable for in vitro assays requiring control or synchronization of cell activities as well as thermobiology studies.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Niklas Herrmann, Cristina Martin, Samuel Eyley, Yusen Li, Nerea Bilbao, Victor Rubio-Gimenez, Mark Van der Auweraer, Wim Thielemans, Long Chen, Kunal S. Mali, Steven De Feyter
Summary: This article reports the rapid reaction kinetics of a 2D polymer based on imine, which is formed from a single monomer containing both aldehyde and amine groups. The results suggest a direct transition from monomer to crystalline polymer without an amorphous intermediate.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Yong Zhou, Martine Trentesaux, Maya Marinova, Sergei Chernyak, Jean-Charles Morin, Melanie Dubois, Samuel Eyley, Wim Thielemans, Vlad Martin-Diaconescu, Andrei Khodakov, Jeremie Zaffran, Vitaly Ordomsky
Summary: In conventional bifunctional catalysts, metal sites are responsible for catalytic activity, while acid sites are typically located on oxide supports. This study investigates the modification of metal sites with halogens to generate acidity through the heterolytic dissociation of hydrogen. High-throughput screening of different combinations of metals (Co, Ni, Ru, Pt, Pd, Rh) and halogens (Cl, Br, I) reveals that only Pd and Pt catalysts can form acid sites through interaction with Br, Cl, and I. Characterization and density functional theory (DFT) modeling suggest that hydrogen undergoes heterolytic dissociation over halogens located at the edges and corners of Pd and Pt nanoparticles, with the strength of the acid sites increasing with the electronegativity of the halogen.
Article
Materials Science, Multidisciplinary
Anna Trubetskaya, Jenni Leppiniemi, Sami Lipponen, Salvatore Lombardo, Wim Thielemans, Thaddeus Maloney, Timo Paeaekkoenen, Kavindra Kumar Kesari, Janne Ruokolainen, Vesa P. Hytoenen, Eero Kontturi
Summary: In this study, a thermoresponsive and biocompatible hydrogel composed of poly(N-isopropylacrylamide) (PNIPAAm) and cellulose nanocrystals (CNC) was developed. The hydrogel was generated through simple mixing without complicated derivatization, and its composition was optimized to enhance its stiffness. The hydrogel showed good compatibility with fibroblast cells and its thermoresponsive characteristics were observed. The findings suggest that this PNIPAAm-CNC hydrogel can be used as a versatile and affordable material for controllable 3D cell culture and may have potential applications in 3D-printing.
MATERIALS ADVANCES
(2023)
Article
Chemistry, Physical
Tim de la Croix, Nathalie Claes, Samuel Eyley, Wim Thielemans, Sara Bals, Dirk De Vos
Summary: This study investigates the potential of using heterogeneous platinum catalysts for the transfer dehydrogenation of long-chain alkanes, using ethylene as a hydrogen acceptor. The results show that the addition of tin to the catalyst leads to lower initial reaction rates but better resistance to catalyst deactivation and increased selectivity towards alkylaromatics.
CATALYSIS SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
Valentin P. Beyer, Jonas Blockx, Ayessa Pires Maciel, Sakshi Tyagi, Irem Demir-Yilmaz, Cecile Formosa-Dague, Koenraad Muylaert, Wim Thielemans
Summary: In this study, we synthesised a library of PDMAEMA polymers and used them for flocculation of Chlorella vulgaris. The dose required for flocculation was independent of polymer molecular weight, and flocculation primarily occurred through charge neutralisation. High molecular weight PDMAEMA caused surface charge reversal and dispersion restabilization, while low molecular weight PDMAEMA did not.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Hongshan Zhu, Stephan Heinitz, Samuel Eyley, Wim Thielemans, Elien Derveaux, Peter Adriaensens, Koen Binnemans, Steven Mullens, Thomas Cardinaels
Summary: In this study, the effects of gamma radiation on AG MP-50 cation exchange resin and sulfonated activated carbon (SAC) were investigated. It was found that the surface sulfonic acid groups of AG MP-50 resin suffered severe radiation-induced degradation, while no apparent changes in acquired morphological characteristics were observed for SAC. The sorption performance of both materials for La3+ and Bi3+ remained generally the same.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
