Article
Agricultural Engineering
Haichao Li, Xin Li, Deqiang Li, Jiankang Zhang, Haq Nawaz, Tingting You, Feng Xu
Summary: Short-time alkaline enhanced aqueous DES pretreatment using choline chloride/ethylene glycol significantly reduced pretreatment time and achieved high sugar yield and lignin extraction rate, showing industrial potential.
BIORESOURCE TECHNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Hongsen Zhang, Chenqing Fu, Tianbao Ren, Hui Xie, Guotao Mao, Zhimin Wang, Fengqin Wang, Andong Song
Summary: The use of 0.8% sulfuric acid presoak combined with ICSE pretreatment can effectively remove nicotine from tobacco stalk, increase total sugar concentration and ethanol yield after enzymatic hydrolysis, ultimately achieving efficient utilization of discarded tobacco stalk.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Agricultural Engineering
Jie Wu, Mahmood Ebadian, Kwang Ho Kim, Chang Soo Kim, Jack Saddler
Summary: Densified wood pellets are a promising biomass feedstock, but storage and handling issues arise due to their friability and hygroscopic nature. Pre-steaming the biomass enhances pellet durability and binding, but drying and pelletization impede enzymatic hydrolysis. Addition of chemical steps before pre-steaming and mechanical refining can mitigate these negative effects.
BIORESOURCE TECHNOLOGY
(2022)
Article
Agricultural Engineering
Hongqiong Zhang, Rui Zhang, Yunong Song, Xinying Miu, Quanguo Zhang, Jingbo Qu, Yong Sun
Summary: This study investigated the effects of using urea combined with steam explosion on the enzymatic hydrolysis and ethanol production of corn stover. The results showed that optimal conditions for ethanol production were 4.87% urea addition and 1.22 MPa steam pressure. The addition of urea and steam explosion significantly increased the reducing sugar yield and degradation rates of cellulose, hemicellulose, and lignin.
BIORESOURCE TECHNOLOGY
(2023)
Article
Energy & Fuels
Marlen Trejo, Prakash Bhuyar, Gomathi Velu, Evelyn Zamudio Perez, Yuwalee Unpaprom, Anongkorn Trail, Rameshprabu Ramaraj
Summary: This study investigated the synthesis of ethanol from dried elephant ear plants and evaluated the effects of different treatment conditions on ethanol production. Under the most favorable conditions, fermentation resulted in high concentrations of ethanol. This research provides a new method for ethanol production.
Article
Nutrition & Dietetics
Zhi-Min Zhao, Wenqing Yu, Caitong Huang, Huiting Xue, Juan Li, Dejian Zhang, Guanhua Li
Summary: Enzymatic hydrolysis and steam explosion were used to improve the fermentable sugar content and cellulose accessibility of tiger nut, enhancing its value-added utilization.
FRONTIERS IN NUTRITION
(2023)
Article
Agricultural Engineering
Wenjie Sui, Xiaoqian Liu, Hao Sun, Chao Li, Ashak Mahmud Parvez, Guanhua Wang
Summary: This study introduces a novel combined pretreatment approach involving steam explosion and GVL/water delignification to improve the enzymatic saccharification efficiency of corn stalk. The method effectively removes lignin and enhances glucan content in the solid material, leading to significantly increased glucose concentration during high-solid loading enzymatic hydrolysis with relatively low cellulase addition. The combined pretreatment shows promise for green lignocellulosic biorefinery by fractionating corn stalk and producing a glucan-enriched solid with enhanced enzymatic digestibility.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Agricultural Engineering
Federico Battista, Luca Zuliani, Fabio Rizzioli, Salvatore Fusco, David Bolzonella
Summary: This study explored a cascade biorefinery approach to produce biodiesel, fermentable sugars, and biomethane from spent coffee grounds, rich in high-value compounds. Transesterification and glycerol pretreatment were used to achieve high product performance. However, the low content of easily degradable compounds led to the need to search for better alternatives to improve methane production.
BIORESOURCE TECHNOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Meenu Hans, Shruti Garg, Vanessa O. A. Pellegrini, Jefferson G. Filgueiras, Eduardo R. de Azevedo, Francisco E. C. Guimaraes, Anuj Kumar Chandel, Igor Polikarpov, Bhupinder Singh Chadha, Sachin Kumar
Summary: The study optimized the conditions for liquid ammonia pretreatment of sugarcane bagasse and achieved a high yield of reducing sugars during enzymatic hydrolysis. The efficiency of the process was further validated through biophysical techniques, confirming the structural and compositional changes of the biomass.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Chemistry, Multidisciplinary
Yawei Zhan, Meixin Wang, Tengfei Ma, Zhiqiang Li
Summary: This study investigated the effect of the GVL/H2O pretreatment system on bamboo for enzymatic hydrolysis and ethanol fermentation. The results showed that the cellulose in bamboo could be effectively separated and converted into bioethanol through the GVL/H2O pretreatment system, with a high conversion yield. The recovered substrates could also be used for other high-valued utilization, and the fermentation inhibitors formed after pretreatment had weak inhibition to the subsequent reaction.
Article
Food Science & Technology
Lan Wang, Tairan Pang, Feng Kong, Hongzhang Chen
Summary: Steam explosion pretreatment improves the extrusion performance of wheat bran, resulting in smaller particle sizes and higher cell wall breakage. The treated wheat bran has increased levels of water-extracted arabinoxylan and soluble dietary fiber, and also shows superior content of total phenol and flavonoids compared to raw wheat bran.
Article
Thermodynamics
V. Rooni, N. Sjulander, A. Cristobal-Sarramian, M. Raud, Lisandra Rocha-Meneses, T. Kikas
Summary: The study showed that steam explosion and nitrogen explosive decompression pretreatment of aspen can increase bioethanol and biogas yields, with steam explosion resulting in higher glucose yields at higher temperatures, and nitrogen explosive decompression being more efficient at lower temperatures.
Article
Chemistry, Physical
Felipe Vedovatto, Gustavo Ugalde, Charline Bonatto, Suzana F. Bazoti, Helen Treichel, Marcio A. Mazutti, Giovani L. Zabot, Marcus Tres
Summary: The study evaluated the subcritical water hydrolysis of soybean straw and hull to obtain fermentable sugars under different temperature and liquid/solid mass ratios, with the condition of 220 degrees C/R-18 and R-15 providing the highest reducing sugars yield and efficiency.
JOURNAL OF SUPERCRITICAL FLUIDS
(2021)
Article
Agricultural Engineering
Li-Yang Liu, Richard P. Chandra, Yong Tang, Xiao-Yan Huang, Feng-Wu Bai, Chen-Guang Liu
Summary: The instant catapult steam explosion (ICSE) is an alternative pre-processing method that can reduce the cost of biomass transportation and chemical pretreatment, while improving the microstructure and enzymatic degradability of the feedstocks.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Agricultural Engineering
Preeti Singh, Neha Srivastava, Akbar Mohammad, Basant Lal, Rajeev Singh, Asad Syed, Abdallah M. Elgorban, Meenakshi Verma, P. K. Mishra, Vijai Kumar Gupta
Summary: The study focuses on the fabrication of carbon-based nanocatalyst (CNCs) using Kans grass biomass (KGB) and its application in enhancing microbial cellulase for sugar production. Different pretreatments were applied to produce CNCs from KGB, which influenced the pretreatment, cellulase production, stability, and sugar recovery. The study found that using 1.0% CNCs pretreated KGB-based solid-state fermentation, high enzyme yields were obtained, and 42 degrees C was identified as the optimal temperature for cellulase production.
BIORESOURCE TECHNOLOGY
(2023)
Review
Environmental Sciences
A. Naresh Kumar, Omprakash Sarkar, K. Chandrasekhar, Tirath Raj, Vivek Narisetty, S. Venkata Mohan, Ashok Pandey, Sunita Varjani, Sunil Kumar, Pooja Sharma, Byong-Hun Jeon, Min Jang, Sang-Hyoun Kim
Summary: The review highlights the advantages and limitations of anaerobic fermentation and biogas CO2 fixation for SA synthesis, as well as the utilization of digestate rich in VFA for MCFA synthesis, demonstrating the significant contribution of integrated approaches to promote circular bioeconomy development in alignment with sustainable development goals.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Agricultural Engineering
K. Chandrasekhar, Tirath Raj, S. V. Ramanaiah, Gopalakrishnan Kumar, Byong-Hun Jeon, Min Jang, Sang-Hyoun Kim
Summary: Anaerobic digestion is a biological process for treating carbon-rich wastes and generating renewable energy. Bioelectrochemical systems are being studied extensively as a hybrid technology to overcome limitations of anaerobic digestion and make the process economically viable. By utilizing BES as a pre-treatment step, biogas and residual metabolites can be upgraded to value-added chemicals and fuels.
BIORESOURCE TECHNOLOGY
(2022)
Review
Agricultural Engineering
Tirath Raj, K. Chandrasekhar, A. Naresh Kumar, J. Rajesh Banu, Jeong-Jun Yoon, Shashi Kant Bhatia, Yung-Hun Yang, Sunita Varjani, Sang-Hyoun Kim
Summary: Cellulosic ethanol production is facing major sustainability issues due to changes in feedstock composition, natural resistance, and lack of cost-effective pretreatment and downstream processing. To address these challenges, a global overview of current cellulosic ethanol facilities, main roadblocks, and technical challenges has been outlined, along with advancements in R&D and solutions for low-cost sustainable fuel ethanol production.
BIORESOURCE TECHNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
K. Chandrasekhar, Tirath Raj, S. Ramanaiah, Gopalakrishnan Kumar, J. Rajesh Banu, Sunita Varjani, Pooja Sharma, Ashok Pandey, Sunil Kumar, Sang-Hyoun Kim
Summary: This review examines the characteristics and potential of microalgae refinements for various applications. By increasing the integration of microalgae with other biorefinery uses, their sustainability can be improved.
JOURNAL OF BIOTECHNOLOGY
(2022)
Review
Chemistry, Physical
Reeta Rani Singhania, Anil Kumar Patel, Tirath Raj, Mei-Ling Tsai, Chiu-Wen Chen, Cheng-Di Dong
Summary: The increasing demand for energy resources due to population growth and industrialization has led to the exploration of alternative renewable fuels, with bio-ethanol produced from lignocellulosic biomass being the most popular. However, challenges such as inducible enzyme secretion by fungi and the complicated structure of biomass hinder the efficient production of ethanol. This article discusses the challenges and possible solutions for cellulase action on cellulosic biomass at a high solid loading, highlighting the need for biomass pretreatment to enhance enzyme efficiency.
Article
Biotechnology & Applied Microbiology
Periyasamy Sivagurunathan, Tirath Raj, Prakram Singh Chauhan, Pallavi Kumari, Alok Satlewal, Ravi Prakash Gupta, Ravindra Kumar
Summary: Lignocellulosic biomasses are promising feedstocks for the production of high-value chemicals, and this study demonstrates a method for high-titer lactic acid fermentation from pretreated rice straw, resulting in high production and conversion yields.
BIOCHEMICAL ENGINEERING JOURNAL
(2022)
Article
Agricultural Engineering
Tirath Raj, K. Chandrasekhar, Raj Morya, Ashutosh Kumar Pandey, Ju-Hyeong Jung, Deepak Kumar, Reeta Rani Singhania, Sang-Hyoun Kim
Summary: The global increase in population and economy has led to a rise in organic waste, particularly food waste. Improper disposal techniques have resulted in the wastage of carbohydrate-rich feedstocks, causing severe environmental issues. This review examines advanced valorization strategies that utilize organic material in food waste as a carbon source for microbial digestion and the generation of value-added compounds. It highlights the importance of pretreatment methods in extracting sugars for microbial digestion, while also addressing the challenges posed by toxins and inhibitors produced during pretreatment. The potential of food waste integrated biorefineries and future perspectives are also discussed.
BIORESOURCE TECHNOLOGY
(2022)
Article
Environmental Sciences
Tirath Raj, K. Chandrasekhar, Jungsu Park, Sunita Varjani, Pooja Sharma, Deepak Kumar, Jeong-Jun Yoon, Ashok Pandey, Sang-Hyoun Kim
Summary: The leaching of cobalt and nickel into water streams has negative environmental and human health impacts. This study focuses on developing cost-effective and environmentally friendly technologies for recovering these heavy metals. Two new fatty acid-based ionic liquids were synthesized and successfully used to extract cobalt and nickel from aqueous solutions.
Article
Agricultural Engineering
Tirath Raj, Raj Morya, K. Chandrasekhar, Deepak Kumar, Shveta Soam, Ravindra Kumar, Anil Kumar Patel, Sang-Hyoun Kim
Summary: Microalgae can convert CO2 into carbohydrates, lipids, and proteins, which can be transformed into renewable energy, chemicals, and materials. However, the difficult-to-degrade cell wall and lack of environmentally friendly pretreatment methods hinder the commercialization of microalgal biorefineries. This article discusses the chemical structure and rigidity of microalgae, and summarizes traditional pretreatment methods. Green solvents like ionic liquids, deep eutectic solvents, and natural deep eutectic solvents show promise in selectively extracting components from microalgae. Further research is needed for the deployment of carbon-neutral technologies, including the design of task-specific solvents, understanding their structural activity, and assessing their environmental toxicity and recyclability. Additionally, integrating microalgal industry with biorefineries can improve waste management, sustainability, and revenue.
BIORESOURCE TECHNOLOGY
(2023)
Review
Agricultural Engineering
Raj Morya, Tirath Raj, Youngkyu Lee, Ashutosh Kumar Pandey, Deepak Kumar, Reeta Rani Singhania, Saurabh Singh, Jay Prakash Verma, Sang-Hyoun Kim
Summary: This review discusses the pathways for biohydrogen production, including thermochemical and biotechnological approaches. The utilization of renewable energy sources in environmentally friendly technologies can lead to high-yield, low-cost bioenergy transition.
BIORESOURCE TECHNOLOGY
(2022)
Review
Agricultural Engineering
Ashutosh Kumar Pandey, Jungsu Park, Jeun Ko, Hwan-Hong Joo, Tirath Raj, Lalit Kumar Singh, Noopur Singh, Sang-Hyoun Kim
Summary: Hydrogen can be produced in an environmentally friendly manner using various organic waste and biomass as feedstock. However, the complexity of biological processes limits their predictability and reliability, hindering scale-up and dissemination. This article reviews the use of machine learning in biohydrogen production technology, which has shown promise in modeling and predicting process performance and microbial population dynamics. Further research on machine learning is needed for designing process control tools and understanding the connection between process performance and microbial populations.
BIORESOURCE TECHNOLOGY
(2023)
Article
Environmental Sciences
Vaibhav Sunil Tambat, Anil Kumar Patel, Chiu-Wen Chen, Tirath Raj, Jo-Shu Chang, Reeta Rani Singhania, Cheng-Di Dong
Summary: Globally, environmental concerns are increasing due to pollution levels, particularly hazardous heavy metals like vanadium. This study aims to develop a sustainable method for vanadium removal and utilize the biomass for biofuels, addressing the lack of green treatment methods. The use of microalgae for vanadium treatment has shown promising results, with significant improvement in removal efficiency after optimizing key parameters.
ENVIRONMENTAL POLLUTION
(2023)
Article
Agricultural Engineering
Tirath Raj, Sandhya Sompura, K. Chandrasekhar, Sushil Kumar Singh, Srinath Pandey, Lalit Kumar Singh, Manish Singh Rajput, Deepak Kumar, Shashi Kant Bhatia, Anil Kumar Patel, Reeta Rani Singhania
Summary: This paper examines the issues in municipal solid waste production and management, and discusses the generation of diverse bioproducts from organic waste. By converting organic waste into fuel and chemicals, it is possible to reduce waste, increase energy output, and provide additional healthcare commodities. This contributes to achieving high levels of energy security, environmental protection, and a more robust bioeconomy.
BIOMASS & BIOENERGY
(2023)
Article
Agricultural Engineering
Neha Chandel, Kinnri Jain, Ankit Jain, Tirath Raj, Anil Kumar Patel, Yung-Hun Yang, Shashi Kant Bhatia
Summary: Cellulose is a versatile natural biopolymer that can be obtained from plants or produced through microbial fermentation. It possesses desirable properties, including biodegradability, biocompatibility, noncytotoxicity, nongenotoxicity, and easy modification, making it highly suitable for biomedical and pharmaceutical applications. Surface modification, blending with other natural polymers, or incorporation of metal-based nanoparticles can enhance its thermal, surface, and mechanical properties. Cellulose-based materials, such as nanocomposites, graft copolymers, and nanocrystals, have been extensively investigated for use in various industries, including food, textiles, wastewater treatment, biomedical engineering, and drug delivery systems. This review provides insights into cellulose production and modification for the development of high-value-added materials in biomedical applications.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biotechnology & Applied Microbiology
Raj Morya, Fanirintsoa Herivonona Andrianantenaina, Saurabh Singh, Ashutosh Kumar Pandey, Gi-Beom Kim, Jay Prakash Verma, Gopalakrishnan Kumar, Tirath Raj, Sang-Hyoun Kim
Summary: Due to the high demand for rice as a main food crop, the disposal of rice straw becomes a significant waste management issue in rice-producing countries. Open burning is the most common method but it causes environmental problems. However, utilizing rice straw as a raw material for valuable products can be advantageous. This review highlights the use of rice straw as a crucial source of clean energy.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
