Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics

Mitochondria-lysosome contact site dynamics and misregulation in neurodegenerative diseases

(2022) Jasmine Cisneros et al.   TRENDS IN NEUROSCIENCES

Dominant mutations in MIEF1 affect mitochondrial dynamics and cause a singular late onset optic neuropathy

(2021) Majida Charif et al.   Molecular Neurodegeneration

Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease

(2021) Soojin Kim et al.   Nature Communications

SKIP ‐ HOPS recruits TBC 1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport

(2020) Marlieke LM Jongsma et al.   EMBO JOURNAL

Regulation and Function of Mitochondria–Lysosome Membrane Contact Sites in Cellular Homeostasis

(2019) Yvette C. Wong et al.   TRENDS IN CELL BIOLOGY

New interfaces on MiD51 for Drp1 recruitment and regulation

(2019) Jun Ma et al.   PLoS One

Lysosomal Regulation of Inter-mitochondrial Contact Fate and Motility in Charcot-Marie-Tooth Type 2

(2019) Yvette C. Wong et al.   DEVELOPMENTAL CELL

Lysosomes as a therapeutic target

(2019) Srinivasa Reddy Bonam et al.   NATURE REVIEWS DRUG DISCOVERY

Lysosomes as dynamic regulators of cell and organismal homeostasis

(2019) Andrea Ballabio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A brain-enriched Drp1 isoform associates with lysosomes, late endosomes and the plasma membrane

(2018) Kie Itoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

(2018) Yvette C. Wong et al.   NATURE

Rab GTPase Function in Endosome and Lysosome Biogenesis

(2018) Lars Langemeyer et al.   TRENDS IN CELL BIOLOGY

Structural basis of mitochondrial receptor binding and constriction by DRP1

(2018) Raghav Kalia et al.   NATURE

EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms

(2018) Weston Stauffer et al.   Scientific Reports

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff

(2017) Rong Yu et al.   Scientific Reports

Drp1, Mff, Fis1, and MiD51 are coordinated to mediate mitochondrial fission during UV irradiation–induced apoptosis

(2016) Zhenzhen Zhang et al.   FASEB JOURNAL

Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission

(2016) Laura D. Osellame et al.   JOURNAL OF CELL SCIENCE

Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor

(2015) Ryan W. Clinton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity

(2015) Patrick J. Macdonald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1

(2015) Raymond Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Treatment strategies for inherited optic neuropathies: past, present and future

(2014) P Yu-Wai-Man et al.   EYE

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission

(2014) Viviane Richter et al.   JOURNAL OF CELL BIOLOGY

The Mitochondrial Fission Receptor MiD51 Requires ADP as a Cofactor

(2014) Oliver C. Losón et al.   STRUCTURE

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy

(2014) Koji Yamano et al.   eLife

Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission

(2013) S. Koirala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology

(2012) Kenta Onoue et al.   JOURNAL OF CELL SCIENCE

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

(2011) Jian Zhao et al.   EMBO JOURNAL

MiD49 and MiD51, new components of the mitochondrial fission machinery

(2011) Catherine S Palmer et al.   EMBO REPORTS

An Enhanced Monomeric Blue Fluorescent Protein with the High Chemical Stability of the Chromophore

(2011) Oksana M. Subach et al.   PLoS One

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Differential Effects of TBC1D15 and Mammalian Vps39 on Rab7 Activation State, Lysosomal Morphology, and Growth Factor Dependence

(2010) Eigen R. Peralta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Rubicon controls endosome maturation as a Rab7 effector

(2010) Q. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab7 Activation by Growth Factor Withdrawal Contributes to the Induction of Apoptosis

(2009) Kimberly Romero Rosales et al.   MOLECULAR BIOLOGY OF THE CELL

The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells

(2008) Shilpa Gandre-Babbe et al.   MOLECULAR BIOLOGY OF THE CELL