Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity

Splitting up the powerhouse: structural insights into the mechanism of mitochondrial fission

(2015) Viviane Richter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor

(2015) Ryan W. Clinton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanoenzymatic Core of Dynamin-related Protein 1 Comprises the Minimal Machinery Required for Membrane Constriction

(2015) Christopher A. Francy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane curvature at a glance

(2015) H. T. McMahon et al.   JOURNAL OF CELL SCIENCE

Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission

(2015) Natalia Stepanyants et al.   MOLECULAR BIOLOGY OF THE CELL

The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1

(2015) Raymond Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal structure of the dynamin tetramer

(2015) Thomas F. Reubold et al.   NATURE

A hemi-fission intermediate links two mechanistically distinct stages of membrane fission

(2015) Juha-Pekka Mattila et al.   NATURE

Determinants and Functions of Mitochondrial Behavior

(2014) Katherine Labbé et al.   Annual Review of Cell and Developmental Biology

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission

(2014) Viviane Richter et al.   JOURNAL OF CELL BIOLOGY

Alternate pleckstrin homology domain orientations regulate dynamin-catalyzed membrane fission

(2014) Niharika Mehrotra et al.   MOLECULAR BIOLOGY OF THE CELL

A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission

(2014) Patrick J. Macdonald et al.   MOLECULAR BIOLOGY OF THE CELL

Specific Interaction with Cardiolipin Triggers Functional Activation of Dynamin-Related Protein 1

(2014) Itsasne Bustillo-Zabalbeitia et al.   PLoS One

The Mitochondrial Fission Receptor MiD51 Requires ADP as a Cofactor

(2014) Oliver C. Losón et al.   STRUCTURE

Dynamin Assembly Strategies and Adaptor Proteins in Mitochondrial Fission

(2013) Huyen T. Bui et al.   CURRENT BIOLOGY

Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein

(2013) Chris Fröhlich et al.   EMBO JOURNAL

Adaptor Proteins MiD49 and MiD51 Can Act Independently of Mff and Fis1 in Drp1 Recruitment and Are Specific for Mitochondrial Fission

(2013) Catherine S. Palmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules

(2013) Stefan Strack et al.   JOURNAL OF CELL BIOLOGY

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

(2013) Oliver C. Losón et al.   MOLECULAR BIOLOGY OF THE CELL

Functional Mapping of Human Dynamin-1-Like GTPase Domain Based on X-ray Structure Analyses

(2013) Julia Wenger et al.   PLoS One

Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission

(2013) S. Koirala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Trafficking in Neurons

(2013) T. L. Schwarz   Cold Spring Harbor Perspectives in Biology

Curvature, Lipid Packing, and Electrostatics of Membrane Organelles: Defining Cellular Territories in Determining Specificity

(2012) Joëlle Bigay et al.   DEVELOPMENTAL CELL

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

The regulation of mitochondrial morphology: Intricate mechanisms and dynamic machinery

(2011) Catherine S. Palmer et al.   CELLULAR SIGNALLING

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

(2011) Jian Zhao et al.   EMBO JOURNAL

MiD49 and MiD51, new components of the mitochondrial fission machinery

(2011) Catherine S Palmer et al.   EMBO REPORTS

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients

(2010) Jon A Kenniston et al.   EMBO JOURNAL

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission

(2010) Jason A Mears et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons

(2009) Takuma Uo et al.   EXPERIMENTAL NEUROLOGY

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

(2009) Junko Wakabayashi et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

Mechanistic Analysis of a Dynamin Effector

(2009) L. L. Lackner et al.   SCIENCE

Integration of tail-anchored proteins into the mitochondrial outer membrane does not require any known import components

(2008) C. Kemper et al.   JOURNAL OF CELL SCIENCE

The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells

(2008) Shilpa Gandre-Babbe et al.   MOLECULAR BIOLOGY OF THE CELL