Integrated Nanovaccine with MicroRNA-148a Inhibition Reprograms Tumor-Associated Dendritic Cells by Modulating miR-148a/DNMT1/SOCS1 Axis

Nanovaccine loaded with poly I:C and STAT3 siRNA robustly elicits anti-tumor immune responses through modulating tumor-associated dendritic cells in vivo

(2015) Zichao Luo et al.   BIOMATERIALS

Immunotherapy: The Path to Win the War on Cancer?

(2015)   CELL

The role of DNA methylation in directing the functional organization of the cancer epigenome

(2015) Fides D. Lay et al.   GENOME RESEARCH

MicroRNAs affect dendritic cell function and phenotype

(2015) Lesley A. Smyth et al.   IMMUNOLOGY

Tumor-Infiltrating Dendritic Cells in Cancer Pathogenesis

(2015) Jo Marie Tran Janco et al.   JOURNAL OF IMMUNOLOGY

Chemotherapeutic Targeting of Cancer-Induced Immunosuppressive Cells

(2014) D. Alizadeh et al.   CANCER RESEARCH

Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells

(2014) Shanshan Wan et al.   GASTROENTEROLOGY

Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level

(2014) Lotte Pyfferoen et al.   INTERNATIONAL JOURNAL OF CANCER

The role of miR-148a in gastric cancer

(2014) Jiazeng Xia et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Immunoregulation of Dendritic Cells by the Receptor T cell Ig and Mucin Protein-3 via Bruton’s Tyrosine Kinase and c-Src

(2014) Neeraj Maurya et al.   JOURNAL OF IMMUNOLOGY

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages

(2014) Chang Cheng et al.   TOXICOLOGY LETTERS

DNA methylation dynamics during ex vivo differentiation and maturation of human dendritic cells

(2014) Xue Zhang et al.   Epigenetics & Chromatin

Trial Watch

(2014) Fernando Aranda et al.   OncoImmunology

MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells

(2013) J. J. Karrich et al.   BLOOD

Myeloid-Derived Suppressor Cells Enhance Stemness of Cancer Cells by Inducing MicroRNA101 and Suppressing the Corepressor CtBP2

(2013) Tracy X. Cui et al.   IMMUNITY

Inactivation of tumor-specific CD8+ CTLs by tumor-infiltrating tolerogenic dendritic cells

(2013) Hirotomo Harimoto et al.   IMMUNOLOGY AND CELL BIOLOGY

Toll-like receptor agonists: current status and future perspective on their utility as adjuvants in improving antic ancer vaccination strategies

(2013) Constantin N Baxevanis et al.   Immunotherapy

T Cell Receptor (TCR) and Transforming Growth Factor β (TGF-β) Signaling Converge on DNA (Cytosine-5)-methyltransferase to Controlforkhead box protein 3(foxp3) Locus Methylation and Inducible Regulatory T Cell Differentiation

(2013) Chaoran Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cationic polypeptide micelle-based antigen delivery system: A simple and robust adjuvant to improve vaccine efficacy

(2013) Zichao Luo et al.   JOURNAL OF CONTROLLED RELEASE

Multiple Tumor-Associated MicroRNAs Modulate the Survival and Longevity of Dendritic Cells by Targeting YWHAZ and Bcl2 Signaling Pathways

(2013) S. Min et al.   JOURNAL OF IMMUNOLOGY

PU.1-Dependent Transcriptional Regulation of miR-142 Contributes to Its Hematopoietic Cell-Specific Expression and Modulation of IL-6

(2013) Y. Sun et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-23b promotes tolerogenic properties of dendritic cells in vitro through inhibiting Notch1/NF-κB signalling pathways

(2012) J. Zheng et al.   ALLERGY

Self-Assembled Cationic Micelles Based on PEG-PLL-PLLeu Hybrid Polypeptides as Highly Effective Gene Vectors

(2012) Jizhe Deng et al.   BIOMACROMOLECULES

Immune suppression in the tumor microenvironment: a role for dendritic cell-mediated tolerization of T cells

(2012) Arthur A. Hurwitz et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

(2012) Shigeki Chiba et al.   NATURE IMMUNOLOGY

Toll-like receptor 3 agonist complexed with cationic liposome augments vaccine-elicited antitumor immunity by enhancing TLR3–IRF3 signaling and type I interferons in dendritic cells

(2012) Ce Wang et al.   VACCINE

A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1

(2012) Qing Xu et al.   Journal of Molecular Cell Biology

Impact of the hypomethylating agent 5-azacytidine on dendritic cells function

(2011) Jihane Frikeche et al.   EXPERIMENTAL HEMATOLOGY

FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer

(2011) Stephanie K. Watkins et al.   JOURNAL OF CLINICAL INVESTIGATION

Microbiota Downregulates Dendritic Cell Expression of miR-10a, Which Targets IL-12/IL-23p40

(2011) X. Xue et al.   JOURNAL OF IMMUNOLOGY

A Parsimonious Model for Gene Regulation by miRNAs

(2011) S. Djuranovic et al.   SCIENCE

Peroxynitrite-Dependent Killing of Cancer Cells and Presentation of Released Tumor Antigens by Activated Dendritic Cells

(2010) Jennifer Fraszczak et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-148/152 Impair Innate Response and Antigen Presentation of TLR-Triggered Dendritic Cells by Targeting CaMKII 

(2010) X. Liu et al.   JOURNAL OF IMMUNOLOGY

Tumor-Infiltrating Regulatory Dendritic Cells Inhibit CD8+ T Cell Function via L-Arginine Metabolism

(2009) L. A. Norian et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Epigenetics: Modifications, Screening, and Therapy

(2007) Gal-Yam Einav Nili et al.   Annual Review of Medicine