Geniposide restricts angiogenesis in experimentary arthritis via inhibiting Dnmt1-mediated PTEN hypermethylation

The anti-angiogenesis mechanism of Geniposide on rheumatoid arthritis is related to the regulation of PTEN

(2022) Yanhong Bu et al.   INFLAMMOPHARMACOLOGY

SIRT6 promotes angiogenesis and hemorrhage of carotid plaque via regulating HIF-1α and reactive oxygen species

(2021) Zhou Yang et al.   Cell Death & Disease

Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis

(2021) Na Lin et al.   Frontiers in Pharmacology

Role of cedazuridine/decitabine in the management of myelodysplastic syndrome and chronic myelomonocytic leukemia

(2021) Swapna Thota et al.   Future Oncology

MiRNA-132 regulates the development of osteoarthritis in correlation with the modulation of PTEN/PI3K/AKT signaling

(2021) Wei Zhang et al.   BMC Geriatrics

High endothelial venules (HEVs) in immunity, inflammation and cancer

(2021) Lucas Blanchard et al.   ANGIOGENESIS

LKB1-PTEN axis controls Th1 and Th17 cell differentiation via regulating mTORC1

(2021) Mahesh Pandit et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Comparative Analysis on Abnormal Methylome of Differentially Expressed Genes and Disease Pathways in the Immune Cells of RA and SLE

(2021) Qinghua Fang et al.   Frontiers in Immunology

Preclinical models of arthritis for studying immunotherapy and immune tolerance

(2021) Gavin R Meehan et al.   ANNALS OF THE RHEUMATIC DISEASES

Geniposide downregulates the VEGF / SphK1 / S1P pathway and alleviates angiogenesis in rheumatoid arthritis in vivo and in vitro

(2021) Yan Wang et al.   PHYTOTHERAPY RESEARCH

The interplay between fibroblast‐like synovial and vascular endothelial cells leads to angiogenesis via the sphingosine‐1‐phosphate‐induced RhoA‐F ‐Actin and Ras‐Erk1 /2 pathways and the intervention of geniposide

(2021) Ran Deng et al.   PHYTOTHERAPY RESEARCH

The DNA methylation Profile of Undifferentiated Arthritis Patients Anticipates their Subsequent Differentiation to Rheumatoid Arthritis

(2021) Carlos de la Calle‐Fabregat et al.   Arthritis & Rheumatology

LncRNA MIR31HG is induced by tocilizumab and ameliorates rheumatoid arthritis fibroblast-like synoviocyte-mediated inflammation via miR-214-PTEN-AKT signaling pathway

(2021) Liang Cao et al.   Aging-US

Plasma S-Adenosylmethionine Is Associated with Lung Injury in COVID-19

(2021) Evgeny Vladimirovich Kryukov et al.   DISEASE MARKERS

Angiogenesis as a potential treatment strategy for rheumatoid arthritis

(2021) Yan Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway

(2021) Limei Ao et al.   MOLECULAR IMMUNOLOGY

Targeting bioenergetics prevents CD4 T cell–mediated activation of synovial fibroblasts in rheumatoid arthritis

(2020) Andreea Petrasca et al.   RHEUMATOLOGY

Vasoinhibin reduces joint inflammation, bone loss, and the angiogenesis and vasopermeability of the pannus in murine antigen-induced arthritis

(2020) Georgina Ortiz et al.   LABORATORY INVESTIGATION

Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patients

(2020) R. Pitaksalee et al.   Clinical Epigenetics

USP13 mediates PTEN to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via AKT-dependent manner

(2020) Jianming Huang et al.   BIOMEDICINE & PHARMACOTHERAPY

Tripterygium wilfordii : An inspiring resource for rheumatoid arthritis treatment

(2020) Yanqiong Zhang et al.   MEDICINAL RESEARCH REVIEWS

Phosphorylation and Driver Mutations in PI3Kα and PTEN Autoinhibition

(2020) Ruth Nussinov et al.   MOLECULAR CANCER RESEARCH

Anti-Inflammatory Effect of Geniposide on Regulating the Functions of Rheumatoid Arthritis Synovial Fibroblasts via Inhibiting Sphingosine-1-Phosphate Receptors1/3 Coupling Gαi/Gαs Conversion

(2020) Rong-hui Wang et al.   Frontiers in Pharmacology

PPARγ preservation via promoter demethylation alleviates osteoarthritis in mice

(2019) Xiaobo Zhu et al.   ANNALS OF THE RHEUMATIC DISEASES

5-Aza-2′-deoxycytidine, a DNA methylation inhibitor, attenuates hypoxic pulmonary hypertension via demethylation of the PTEN promoter

(2019) Xi-Qian Xing et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of Interleukin-34 on Secretion of Angiogenesis Cytokines by Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis

(2019) Lu Lu Ding et al.   IMMUNOLOGICAL INVESTIGATIONS

PTEN negatively regulates the expression of pro-inflammatory cytokines and chemokines of fibroblast-like synoviocytes in adjuvant-induced arthritis

(2019) Xiao-Feng Li et al.   Artificial Cells Nanomedicine and Biotechnology

STAT3 Mediates the Differential Effects of Oncostatin M and TNFα on RA Synovial Fibroblast and Endothelial Cell Function

(2019) Megan M. Hanlon et al.   Frontiers in Immunology

Differential DNA methylation correlates with response to methotrexate in rheumatoid arthritis

(2019) Nisha Nair et al.   RHEUMATOLOGY

Comparative anti-arthritic investigation of iridoid glycosides and crocetin derivatives from Gardenia jasminoides Ellis in Freund's complete adjuvant-induced arthritis in rats

(2018) Yaya Hu et al.   PHYTOMEDICINE

Rheumatoid arthritis–associated DNA methylation sites in peripheral blood mononuclear cells

(2018) Hong Zhu et al.   ANNALS OF THE RHEUMATIC DISEASES

Vascular endothelial growth factor signaling in VE-cadherin expression and tube-like formation by rheumatoid arthritic synovial fibroblast-like cells

(2018) Kosuke Yamaguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Simultaneous determination of bioactive marker compounds from Gardeniae fructus by high performance liquid chromatography

(2013) Eun Ju Lee et al.   ARCHIVES OF PHARMACAL RESEARCH