Pyrogallol enhances therapeutic effect of human umbilical cord mesenchymal stem cells against LPS-mediated inflammation and lung injury via activation of Nrf2/HO-1 signaling

Diversity and versatility of p38 kinase signalling in health and disease

(2021) Begoña Canovas et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mesenchymal Stem Cell-Based Therapy as an Alternative to the Treatment of Acute Respiratory Distress Syndrome: Current Evidence and Future Perspectives

(2021) Silvia Fernández-Francos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice

(2020) Yuto Nakamura et al.   MOLECULAR THERAPY

Mesenchymal stem cell-derived exosomes exert ameliorative effects in type 2 diabetes by improving hepatic glucose and lipid metabolism via enhancing autophagy

(2020) Qin He et al.   Stem Cell Research & Therapy

Mesenchymal stem cell therapy for acute respiratory distress syndrome: from basic to clinics

(2020) Hua Qin et al.   Protein & Cell

Genetic Engineering as a Strategy to Improve the Therapeutic Efficacy of Mesenchymal Stem/Stromal Cells in Regenerative Medicine

(2020) Patricia Kauanna Fonseca Damasceno et al.   Frontiers in Cell and Developmental Biology

Contribution of Nrf2 Modulation to the Mechanism of Action of Analgesic and Anti-inflammatory Drugs in Pre-clinical and Clinical Stages

(2019) Larissa Staurengo-Ferrari et al.   Frontiers in Pharmacology

Nrf2: Redox and Metabolic Regulator of Stem Cell State and Function

(2019) Xiaozhen Dai et al.   TRENDS IN MOLECULAR MEDICINE

Adipose-derived mesenchymal stem cells protect against CMS-induced depression-like behaviors in mice via regulating the Nrf2/HO-1 and TLR4/NF-κB signaling pathways

(2019) Xiao Huang et al.   ACTA PHARMACOLOGICA SINICA

Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation

(2018) Daxiao Sun et al.   CELL RESEARCH

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

(2018) Masayuki Yamamoto et al.   PHYSIOLOGICAL REVIEWS

Activation of p62/SQSTM1–Keap1–Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Cancer

(2018) Yoshinobu Ichimura et al.   Frontiers in Oncology

Mesenchymal stem cells overexpressing heme oxygenase-1 ameliorate lipopolysaccharide-induced acute lung injury in rats

(2018) Xuxin Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Entering the Modern Era of Gene Therapy

(2018) Xavier M. Anguela et al.   Annual Review of Medicine

Butein induction of HO-1 by p38 MAPK/Nrf2 pathway in adipocytes attenuates high-fat diet induced adipose hypertrophy in mice

(2017) Zheng Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nrf2 transfection enhances the efficacy of human amniotic mesenchymal stem cells to repair lung injury induced by lipopolysaccharide

(2017) Shouqin Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Polyphenolics from mango (Mangifera indica L.) suppress breast cancer ductal carcinoma in situ proliferation through activation of AMPK pathway and suppression of mTOR in athymic nude mice

(2017) Matthew J. Nemec et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure

(2017) Zhi-heng Zhang et al.   Stem Cell Research & Therapy

Isoegomaketone Upregulates Heme Oxygenase-1 in RAW264.7 Cells via ROS/p38 MAPK/Nrf2 Pathway

(2016) Chang Hyun Jin et al.   Biomolecules & Therapeutics

Mesenchymal Stem/Stromal Cells in Regenerative Medicine: Can Preconditioning Strategies Improve Therapeutic Efficacy?

(2016) Richard Schäfer et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

Cellular localization of NRF2 determines the self-renewal and osteogenic differentiation potential of human MSCs via the P53–SIRT1 axis

(2016) D S Yoon et al.   Cell Death & Disease

p62 links autophagy and Nrf2 signaling

(2015) Tao Jiang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acethylcholinesterase inhibitory potential and antioxidant properties of pyrogallol

(2015) S. Beyza Ozturk Sarikaya   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates

(2015) Junghyun Lim et al.   PLoS Genetics

Low immunogenicity of allogeneic human umbilical cord blood-derived mesenchymal stem cells in vitro and in vivo

(2014) Miyoung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Umbilical Cord Mesenchymal Stem Cells: The New Gold Standard for Mesenchymal Stem Cell-Based Therapies?

(2014) Reine El Omar et al.   TISSUE ENGINEERING PART B-REVIEWS

Human Umbilical Cord-Derived Mesenchymal Stem Cells Utilize Activin-A to Suppress Interferon-γ Production by Natural Killer Cells

(2014) Debanjana Chatterjee et al.   Frontiers in Immunology

Acute lung injury

(2013) D. Parekh et al.   CLINICAL MEDICINE

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

(2013) Takumi Satoh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade

(2013) Luca Vanella et al.   Stem Cell Research & Therapy

Nrf-2 overexpression in mesenchymal stem cells reduces oxidative stress-induced apoptosis and cytotoxicity

(2012) Mohammad Mohammadzadeh et al.   CELL STRESS & CHAPERONES

Human models of acute lung injury

(2011) A. G. Proudfoot et al.   Disease Models & Mechanisms

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

(2011) K.-i. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients

(2010) Rogier M Determann et al.   BMC Pulmonary Medicine

Pyrogallol induces G2-M arrest in human lung cancer cells and inhibits tumor growth in an animal model

(2009) Chih-Jen Yang et al.   LUNG CANCER

Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response

(2009) Zheng Sun et al.   PLoS One

Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging

(2009) Hui Wang et al.   STEM CELLS