Silencing SIRT5 induces the senescence of UCB-MSCs exposed to TNF-α by reduction of fatty acid β-oxidation and anti-oxidation

TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models

(2022) Jiao Wu et al.   Nature Communications

Sirtuins as Important Factors in Pathological States and the Role of Their Molecular Activity Modulators

(2021) Ewa Maria Kratz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms underlying the therapeutic potential of mesenchymal stem cells in atherosclerosis

(2021) Thomas Kirwin et al.   Regenerative Medicine

TNF-α-mediated m6A modification of ELMO1 triggers directional migration of mesenchymal stem cell in ankylosing spondylitis

(2021) Zhongyu Xie et al.   Nature Communications

sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis

(2021) Yingjie Zhao et al.   Stem Cell Research & Therapy

Evidence that TNF-β suppresses osteoblast differentiation of mesenchymal stem cells and resveratrol reverses it through modulation of NF-κB, Sirt1 and Runx2

(2020) Buhrmann Constanze et al.   CELL AND TISSUE RESEARCH

Sirtuin 5 deficiency increases disease severity in rats with adjuvant-induced arthritis

(2020) Ni Zhang et al.   Cellular & Molecular Immunology

miR‐155‐5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction

(2020) Yimei Hong et al.   AGING CELL

Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

(2020) Ze Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

TNFα/TNFR2 signaling pathway: an active immune checkpoint for mesenchymal stem cell immunoregulatory function

(2020) Ghada Beldi et al.   Stem Cell Research & Therapy

TNFR2 Is a Crucial Hub Controlling Mesenchymal Stem Cell Biological and Functional Properties

(2020) Ghada Beldi et al.   Frontiers in Cell and Developmental Biology

FASN activity is important for the initial stages of the induction of senescence

(2019) Juan Fafián-Labora et al.   Cell Death & Disease

Mesenchymal Stem Cells Improve Rheumatoid Arthritis Progression by Controlling Memory T Cell Response

(2019) Noymar Luque-Campos et al.   Frontiers in Immunology

Regulation of Adaptive Immune Cells by Sirtuins

(2019) Jonathan L. Warren et al.   Frontiers in Endocrinology

TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages

(2019) Harald Wajant et al.   Frontiers in Cell and Developmental Biology

Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI

(2019) Takuto Chiba et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Antioxidant-upregulated mesenchymal stem cells reduce inflammation and improve fatty liver disease in diet-induced obesity

(2019) Cleyton C. Domingues et al.   Stem Cell Research & Therapy

SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway

(2019) Xiaodan Sun et al.   Frontiers in Oncology

SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer

(2019) Chenxia He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nrf2: Redox and Metabolic Regulator of Stem Cell State and Function

(2019) Xiaozhen Dai et al.   TRENDS IN MOLECULAR MEDICINE

Omega-3 fatty acids decrease oxidative stress and inflammation in macrophages from patients with small abdominal aortic aneurysm

(2019) Lara T. Meital et al.   Scientific Reports

Sirt5 Attenuates Cisplatin-Induced Acute Kidney Injury through Regulation of Nrf2/HO-1 and Bcl-2

(2019) Wei Li et al.   Biomed Research International

MSCs protect endothelial cells from inflammatory injury partially by secreting STC1

(2018) Meimei Shi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

IFN-γ and TNF-α Pre-licensing Protects Mesenchymal Stromal Cells from the Pro-inflammatory Effects of Palmitate

(2018) Lauren Boland et al.   MOLECULAR THERAPY

Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications

(2018) Sujuan Yang et al.   Frontiers in Immunology

17β-Estradiol protects mesenchymal stem cells against high glucose-induced mitochondrial oxidants production via Nrf2/Sirt3/MnSOD signaling

(2018) Ji Young Oh et al.   FREE RADICAL BIOLOGY AND MEDICINE

SIRT3 Enhances Mesenchymal Stem Cell Longevity and Differentiation

(2017) Ryan A. Denu   Oxidative Medicine and Cellular Longevity

Effects of Oxidative Stress on Mesenchymal Stem Cell Biology

(2016) Ryan A. Denu et al.   Oxidative Medicine and Cellular Longevity

Fat in flames: influence of cytokines and pattern recognition receptors on adipocyte lipolysis

(2015) Ryan W. Grant et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

(2013) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Timing of Umbilical Cord Blood Derived Mesenchymal Stem Cells Transplantation Determines Therapeutic Efficacy in the Neonatal Hyperoxic Lung Injury

(2013) Yun Sil Chang et al.   PLoS One

Tumor Necrosis Factor-α Signaling in Macrophages

(2012) Narayanan Parameswaran et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

A Manganese Superoxide Dismutase (SOD2)-Mediated Adaptive Response

(2012) David J. Grdina et al.   RADIATION RESEARCH

NF-κB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells

(2011) E Crescenzi et al.   ONCOGENE

Multipotent Stem Cells from Umbilical Cord: Cord Is Richer than Blood!

(2007) Mariane Secco et al.   STEM CELLS