Single cell clonal analysis identifies an AID ‐dependent pathway of plasma cell differentiation

Germinal Centers

(2022) Gabriel D. Victora et al.   Annual Review of Immunology

Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth

(2021) Rinako Nakagawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

(2021) Hamish W. King et al.   Science Immunology

Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response

(2021) Vassilis Glaros et al.   IMMUNITY

Germinal center–dependent and –independent memory B cells produced throughout the immune response

(2021) Charlotte Viant et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow

(2020) René Riedel et al.   Nature Communications

Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome

(2020) Antony B. Holmes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development

(2020) Brian J. Laidlaw et al.   NATURE IMMUNOLOGY

Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses

(2020) Rachel Wong et al.   IMMUNITY

SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data

(2020) Matthew D Young et al.   GigaScience

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Linking signaling and selection in the germinal center

(2019) Mark J. Shlomchik et al.   IMMUNOLOGICAL REVIEWS

Class-Switch Recombination Occurs Infrequently in Germinal Centers

(2019) Jonathan A. Roco et al.   IMMUNITY

Combinatorial prediction of marker panels from single‐cell transcriptomic data

(2019) Conor Delaney et al.   Molecular Systems Biology

T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate

(2018) Wataru Ise et al.   IMMUNITY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity

(2017) Dan Suan et al.   IMMUNITY

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells

(2017) Nike J. Kräutler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection

(2016) Salvador Iborra et al.   IMMUNITY

Germinal Center B Cell Dynamics

(2016) Luka Mesin et al.   IMMUNITY

Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory

(2016) Alexander D. Gitlin et al.   IMMUNITY

A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells

(2016) Florian J. Weisel et al.   IMMUNITY

Regulated selection of germinal-center cells into the memory B cell compartment

(2016) Ryo Shinnakasu et al.   NATURE IMMUNOLOGY

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data: Table 1.

(2015) Namita T. Gupta et al.   BIOINFORMATICS

Apoptosis and antigen affinity limit effector cell differentiation of a single naive B cell

(2015) J. J. Taylor et al.   SCIENCE

circlize implements and enhances circular visualization in R

(2014) Zuguang Gu et al.   BIOINFORMATICS

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Repression of the Transcription Factor Bach2 Contributes to Predisposition of IgG1 Memory B Cells toward Plasma Cell Differentiation

(2013) Kohei Kometani et al.   IMMUNITY

AID and Caspase 8 Shape the Germinal Center Response through Apoptosis

(2013) B. Boulianne et al.   JOURNAL OF IMMUNOLOGY

Fate Mapping for Activation-Induced Cytidine Deaminase (AID) Marks Non-Lymphoid Cells During Mouse Development

(2013) Philipp C. Rommel et al.   PLoS One

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas

(2012) G. D. Victora et al.   BLOOD

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory

(2012) Tomohiro Kaji et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

AID constrains germinal center size by rendering B cells susceptible to apoptosis

(2009) A. Zaheen et al.   BLOOD

AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations

(2008) Davide F. Robbiani et al.   CELL

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY