Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

Myo1e modulates the recruitment of activated B cells to inguinal lymph nodes

(2020) Daniel A. Girón-Pérez et al.   JOURNAL OF CELL SCIENCE

Distinct microbial and immune niches of the human colon

(2020) Kylie R. James et al.   NATURE IMMUNOLOGY

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

(2020) Mirjana Efremova et al.   Nature Protocols

A cell atlas of human thymic development defines T cell repertoire formation

(2020) Jong-Eun Park et al.   SCIENCE

Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome

(2020) Antony B. Holmes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generalizing RNA velocity to transient cell states through dynamical modeling

(2020) Volker Bergen et al.   NATURE BIOTECHNOLOGY

Linking signaling and selection in the germinal center

(2019) Mark J. Shlomchik et al.   IMMUNOLOGICAL REVIEWS

B Cell Responses: Cell Interaction Dynamics and Decisions

(2019) Jason G. Cyster et al.   CELL

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

(2019) Christopher S. McGinnis et al.   Cell Systems

Class-Switch Recombination Occurs Infrequently in Germinal Centers

(2019) Jonathan A. Roco et al.   IMMUNITY

B cell signaling in context

(2019) Kihyuck Kwak et al.   NATURE IMMUNOLOGY

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

BATF regulates the expression of Nfil3 , Wnt10a and miR155hg for efficient induction of antibody class switch recombination in mice

(2018) Rosemary E. Morman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Memory control by the B cell antigen receptor

(2018) Niklas Engels et al.   IMMUNOLOGICAL REVIEWS

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Human germinal center transcriptional programs are de-synchronized in B cell lymphoma

(2018) Pierre Milpied et al.   NATURE IMMUNOLOGY

NME proteins regulate class switch recombination

(2018) Simin Zheng et al.   FEBS LETTERS

B Cell Siglecs–News on Signaling and Its Interplay With Ligand Binding

(2018) Sarah J. Meyer et al.   Frontiers in Immunology

CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity

(2017) Dan Suan et al.   IMMUNITY

An atlas of B-cell clonal distribution in the human body

(2017) Wenzhao Meng et al.   NATURE BIOTECHNOLOGY

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Human DDX21 binds and unwinds RNA guanine quadruplexes

(2017) Ewan K.S. McRae et al.   NUCLEIC ACIDS RESEARCH

CD21-/lowB cells in human blood are memory cells

(2016) K. Thorarinsdottir et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Germinal Center B Cell Dynamics

(2016) Luka Mesin et al.   IMMUNITY

Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development

(2016) Renee Gloury et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fc Receptor–like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue–like Memory B Cells

(2016) Huifang Li et al.   JOURNAL OF IMMUNOLOGY

Regulated selection of germinal-center cells into the memory B cell compartment

(2016) Ryo Shinnakasu et al.   NATURE IMMUNOLOGY

Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins

(2016) Samiran Mondal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switching

(2016) Felix Horns et al.   eLife

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data: Table 1.

(2015) Namita T. Gupta et al.   BIOINFORMATICS

The forkhead transcription factor FOXP1 represses human plasma cell differentiation

(2015) M. van Keimpema et al.   BLOOD

Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions

(2015) Marc Seifert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles

(2015) Daniel Gadala-Maria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactivation of IgG-switched memory B cells by BCR-intrinsic signal amplification promotes IgG antibody production

(2015) Johannes Lutz et al.   Nature Communications

pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires

(2014) Jason A. Vander Heiden et al.   BIOINFORMATICS

No receptor stands alone: IgG B-cell receptor intrinsic and extrinsic mechanisms contribute to antibody memory

(2014) Yinsheng Xu et al.   CELL RESEARCH

Ligation of human Fc receptor like-2 by monoclonal antibodies down-regulates B-cell receptor-mediated signalling

(2014) Mahdi Shabani et al.   IMMUNOLOGY

Transcription Factor IRF4 Regulates Germinal Center Cell Formation through a B Cell-Intrinsic Mechanism

(2014) S. N. Willis et al.   JOURNAL OF IMMUNOLOGY

IgH Chain Class Switch Recombination: Mechanism and Regulation

(2014) Janet Stavnezer et al.   JOURNAL OF IMMUNOLOGY

Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma

(2014) Jagan R. Muppidi et al.   NATURE

Positive Feedback Within a Kinase Signaling Complex Functions as a Switch Mechanism for NF- B Activation

(2014) H. Shinohara et al.   SCIENCE

The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module

(2014) Niklas Engels et al.   Nature Communications

Oct2 and Obf1 as Facilitators of B:T Cell Collaboration during a Humoral Immune Response

(2014) Lynn Corcoran et al.   Frontiers in Immunology

Lymphocyte cytosolic protein 1 is a chronic lymphocytic leukemia membrane-associated antigen critical to niche homing

(2013) J. A. Dubovsky et al.   BLOOD

Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation

(2013) C. Huang et al.   BLOOD

IgBLAST: an immunoglobulin variable domain sequence analysis tool

(2013) Jian Ye et al.   NUCLEIC ACIDS RESEARCH

Subscriptions

(2012)   NUCLEIC ACIDS RESEARCH

Activation-Induced B Cell Fates Are Selected by Intracellular Stochastic Competition

(2012) K. R. Duffy et al.   SCIENCE

Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90

(2010) Alexandre Orthwein et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Plasticity and Heterogeneity in the Generation of Memory B Cells and Long-Lived Plasma Cells: The Influence of Germinal Center Interactions and Dynamics

(2010) K. L. Good-Jacobson et al.   JOURNAL OF IMMUNOLOGY

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

(2010) Ricardo C Ferreira et al.   NATURE GENETICS

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

(2009) Derrick J. Todd et al.   JOURNAL OF EXPERIMENTAL MEDICINE

FCRL3, an Autoimmune Susceptibility Gene, Has Inhibitory Potential on B-Cell Receptor-Mediated Signaling

(2009) Y. Kochi et al.   JOURNAL OF IMMUNOLOGY

Multiple layers of B cell memory with different effector functions

(2009) Ismail Dogan et al.   NATURE IMMUNOLOGY

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

CD72, a Coreceptor with Both Positive and Negative Effects on B Lymphocyte Development and Function

(2008) Hsin-Jung Wu et al.   JOURNAL OF CLINICAL IMMUNOLOGY