Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome

CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate

(2022) Yiliang Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Intestinal Inflammation by Dietary Fats

(2021) Abigail R. Basson et al.   Frontiers in Immunology

Emerging concepts in intestinal immune control of obesity-related metabolic disease

(2021) Saad Khan et al.   Nature Communications

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Human gut bacterial metabolism drives Th17 activation and colitis

(2021) Margaret Alexander et al.   Cell Host & Microbe

Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth

(2020) Elena Zagato et al.   Nature Microbiology

Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

(2020) Lin Wu et al.   CELL

Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis

(2019) Mark S. Ladinsky et al.   SCIENCE

Unveiling genomic diversity among members of the Bifidobacterium pseudolongum species, a widely distributed gut commensal of the animal kingdom.

(2019) Gabriele Andrea Lugli et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Daily Sampling Reveals Personalized Diet-Microbiome Associations in Humans

(2019) Abigail J. Johnson et al.   Cell Host & Microbe

The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

(2019) Sara Omenetti et al.   IMMUNITY

Quantifying spatiotemporal variability and noise in absolute microbiota abundances using replicate sampling

(2019) Brian W. Ji et al.   NATURE METHODS

T cell–mediated regulation of the microbiota protects against obesity

(2019) Charisse Petersen et al.   SCIENCE

Innate Lymphoid Cells in the Induction of Obesity

(2019) Takaharu Sasaki et al.   Cell Reports

A high-sugar diet rapidly enhances susceptibility to colitis via depletion of luminal short-chain fatty acids in mice

(2019) Michael Laffin et al.   Scientific Reports

Projected U.S. State-Level Prevalence of Adult Obesity and Severe Obesity

(2019) Zachary J. Ward et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health

(2018) Jun Zou et al.   Cell Host & Microbe

Inhibition of CD36 reduces visceral fat accumulation and improves insulin resistance in diet-induced obese BDNFVal66Metmice

(2018) Jiwon Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

(2018) Moshe Biton et al.   CELL

Interleukin-17/interleukin-17 receptor axis elicits intestinal neutrophil migration, restrains gut dysbiosis and lipopolysaccharide translocation in high-fat diet-induced metabolic syndrome model

(2018) Malena M. Pérez et al.   IMMUNOLOGY

Gut-Specific Delivery of T-Helper 17 Cells Reduces Obesity and Insulin Resistance in Mice

(2017) Chun-Pyo Hong et al.   GASTROENTEROLOGY

Health Effects of Overweight and Obesity in 195 Countries over 25 Years

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

The intestinal microbiota regulates body composition through NFIL3 and the circadian clock

(2017) Yuhao Wang et al.   SCIENCE

The Intestinal Immune System in Obesity and Insulin Resistance

(2016) Daniel A. Winer et al.   Cell Metabolism

Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-Dependent Manner

(2016) Yoshinaga Kawano et al.   Cell Metabolism

A review of recent evidence relating to sugars, insulin resistance and diabetes

(2016) I. A. Macdonald   EUROPEAN JOURNAL OF NUTRITION

Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation

(2016) Pawan Kumar et al.   IMMUNITY

Dietary Patterns and Risk of Inflammatory Bowel Disease in Europe

(2016) Antoine Racine et al.   INFLAMMATORY BOWEL DISEASES

Emerging concepts and future challenges in innate lymphoid cell biology

(2016) Elia D. Tait Wojno et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

(2016) Emanuele Di Angelantonio et al.   LANCET

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis

(2016) Christoph S N Klose et al.   NATURE IMMUNOLOGY

Deregulated Lipid Sensing by Intestinal CD36 in Diet-Induced Hyperinsulinemic Obese Mouse Model

(2016) Marjorie Buttet et al.   PLoS One

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

(2016) G. B. Choi et al.   SCIENCE

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

(2015) Teruyuki Sano et al.   CELL

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells

(2015) Koji Atarashi et al.   CELL

Regulation of Obesity-Related Insulin Resistance with Gut Anti-inflammatory Agents

(2015) Helen Luck et al.   Cell Metabolism

The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease

(2015) Lucile Garidou et al.   Cell Metabolism

Sugar consumption, metabolic disease and obesity: The state of the controversy

(2015) Kimber L. Stanhope   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability

(2015) Jacob S. Lee et al.   IMMUNITY

Induction of Th17 cells by segmented filamentous bacteria in the murine intestine

(2015) Adam M. Farkas et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Structure-Function of CD36 and Importance of Fatty Acid Signal Transduction in Fat Metabolism

(2014) Marta Yanina Pepino et al.   Annual Review of Nutrition

T Cell–Derived IL-22 Amplifies IL-1β–Driven Inflammation in Human Adipose Tissue: Relevance to Obesity and Type 2 Diabetes

(2014) Elise Dalmas et al.   DIABETES

Segmented Filamentous Bacteria Antigens Presented by Intestinal Dendritic Cells Drive Mucosal Th17 Cell Differentiation

(2014) Yoshiyuki Goto et al.   IMMUNITY

Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes

(2014) Xiaoting Wang et al.   NATURE

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

(2014) Yi Yang et al.   NATURE

Consumption of sucrose and high-fructose corn syrup does not increase liver fat or ectopic fat deposition in muscles

(2013) Stephen Bravo et al.   Applied Physiology Nutrition and Metabolism

Sugar, Uric Acid, and the Etiology of Diabetes and Obesity

(2013) R. J. Johnson et al.   DIABETES

Association Between Specific Adipose Tissue CD4+ T-Cell Populations and Insulin Resistance in Obese Individuals

(2013) Elisa Fabbrini et al.   GASTROENTEROLOGY

Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine

(2012) Nicole de Wit et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

(2012) Wolfgang Hueber et al.   GUT

Lymphotoxin regulates commensal responses to enable diet-induced obesity

(2012) Vaibhav Upadhyay et al.   NATURE IMMUNOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Scavenger Receptor CD36 Expression Contributes to Adipose Tissue Inflammation and Cell Death in Diet-Induced Obesity

(2012) Lei Cai et al.   PLoS One

Deficiency in Interferon-γ Results in Reduced Body Weight and Better Glucose Tolerance in Mice

(2011) Nicole Wong et al.   ENDOCRINOLOGY

Pathogenic Role of Scavenger Receptor CD36 in the Metabolic Syndrome and Diabetes

(2011) David J. Kennedy et al.   Metabolic Syndrome and Related Disorders

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Sugar-Sweetened Beverages, Obesity, Type 2 Diabetes Mellitus, and Cardiovascular Disease Risk

(2010) Vasanti S. Malik et al.   CIRCULATION

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

(2009) William O'Connor Jr et al.   NATURE IMMUNOLOGY

Human gut microbiota in obesity and after gastric bypass

(2009) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

(2009) R. L. Silverstein et al.   Science Signaling

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE