Accumulation of phosphorylated p62 is associated with NF-E2-related factor 2 activation in hepatocellular carcinoma

New Strategies in Renal Cell Carcinoma: Targeting the Genetic and Metabolic Basis of Disease

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Frequent alteration of the protein synthesis of enzymes for glucose metabolism in hepatocellular carcinomas

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Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

(2012) Cécile Guichard et al.   NATURE GENETICS

Biogenesis and Cargo Selectivity of Autophagosomes

(2011) Hilla Weidberg et al.   Annual Review of Biochemistry

Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

(2011) Julie Adam et al.   CANCER CELL

Autophagy and Aging

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Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer

(2010) T. Jiang et al.   CANCER RESEARCH

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy, Immunity, and Microbial Adaptations

(2009) Vojo Deretic et al.   Cell Host & Microbe

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues

(2008) Rui Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic Alteration of Keap1 Confers Constitutive Nrf2 Activation and Resistance to Chemotherapy in Gallbladder Cancer

(2008) Tatsuhiro Shibata et al.   GASTROENTEROLOGY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA