Optimizing the Size of Micellar Nanoparticles for Efficient siRNA Delivery

Polyphosphoester-Based Nanoparticles with Viscous Flow Core Enhanced Therapeutic Efficacy by Improved Intracellular Drug Release

(2014) Yin-Chu Ma et al.   ACS Applied Materials & Interfaces

Polycationic Nanoparticles for siRNA Delivery: Comparing ARGET ATRP and UV-Initiated Formulations

(2014) Diane C. Forbes et al.   ACS Nano

A Reduction and pH Dual-Sensitive Polymeric Vector for Long-Circulating and Tumor-Targeted siRNA Delivery

(2014) Jingguo Li et al.   ADVANCED MATERIALS

Dual sensitive and temporally controlled camptothecin prodrug liposomes codelivery of siRNA for high efficiency tumor therapy

(2014) Yan Li et al.   BIOMATERIALS

Improving drug accumulation and photothermal efficacy in tumor depending on size of ICG loaded lipid-polymer nanoparticles

(2014) Pengfei Zhao et al.   BIOMATERIALS

Matrix metalloproteinase 2-responsive micelle for siRNA delivery

(2014) Hong-Xia Wang et al.   BIOMATERIALS

Synthetic Lethal Therapy for KRAS Mutant Non-small-cell Lung Carcinoma with Nanoparticle-mediated CDK4 siRNA Delivery

(2014) Cheng-Qiong Mao et al.   MOLECULAR THERAPY

Investigating the optimal size of anticancer nanomedicine

(2014) L. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polypeptide cationic micelles mediated co-delivery of docetaxel and siRNA for synergistic tumor therapy

(2013) Cuifang Zheng et al.   BIOMATERIALS

Design and evaluation of new pH-sensitive amphiphilic cationic lipids for siRNA delivery

(2013) Anthony S. Malamas et al.   JOURNAL OF CONTROLLED RELEASE

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Doxorubicin Conjugate of Poly(Ethylene Glycol)-Block-Polyphosphoester for Cancer Therapy

(2013) Chun-Yang Sun et al.   Advanced Healthcare Materials

Enhanced siRNA Delivery and Silencing Gold–Chitosan Nanosystem with Surface Charge-Reversal Polymer Assembly and Good Biocompatibility

(2012) Lu Han et al.   ACS Nano

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Self-assembly nanomicelles based on cationic mPEG-PLA-b-Polyarginine(R15) triblock copolymer for siRNA delivery

(2012) Zhi-Xia Zhao et al.   BIOMATERIALS

Diaminododecane-based cationic bolaamphiphile as a non-viral gene delivery carrier

(2012) Majad Khan et al.   BIOMATERIALS

N-acetylgalactosamine functionalized mixed micellar nanoparticles for targeted delivery of siRNA to liver

(2012) Hong-Xia Wang et al.   JOURNAL OF CONTROLLED RELEASE

A Cell-penetrating Helical Polymer For siRNA Delivery to Mammalian Cells

(2012) Nathan P Gabrielson et al.   MOLECULAR THERAPY

Recent Advances in Nonviral Vectors for Gene Delivery

(2011) Xia Guo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chimeric Capsid Protein as a Nanocarrier for siRNA Delivery: Stability and Cellular Uptake of Encapsulated siRNA

(2011) Kyung-mi Choi et al.   ACS Nano

Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing

(2011) Mahesh L. Patil et al.   ACS Nano

Sheddable Ternary Nanoparticles for Tumor Acidity-Targeted siRNA Delivery

(2011) Xian-Zhu Yang et al.   ACS Nano

Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy

(2011) Xian-Zhu Yang et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma

(2010) Hiroto Hatakeyama et al.   ADVANCED DRUG DELIVERY REVIEWS

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles

(2009) Hong Jin et al.   ACS Nano

Reduction-sensitive polymers and bioconjugates for biomedical applications

(2009) Fenghua Meng et al.   BIOMATERIALS

Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice

(2009) Adam D. Judge et al.   JOURNAL OF CLINICAL INVESTIGATION

Understanding the Role of Surface Charges in Cellular Adsorption versus Internalization by Selectively Removing Gold Nanoparticles on the Cell Surface with a I2/KI Etchant

(2009) Eun Chul Cho et al.   NANO LETTERS

Cellular Uptake and Intracellular Pathways of PLL-g-PEG-DNA Nanoparticles

(2008) Tessa Lühmann et al.   BIOCONJUGATE CHEMISTRY

Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells

(2008) Daniel L.J. Thorek et al.   BIOMATERIALS

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Nanoparticle-mediated cellular response is size-dependent

(2008) Wen Jiang et al.   Nature Nanotechnology

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Silencing of Polo-Like Kinase (Plk) 1 via siRNA Causes Inhibition of Growth and Induction of Apoptosis in Human Esophageal Cancer Cells

(2008) Youquan Bu et al.   ONCOLOGY

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA