Artificial Nucleobase-Directed Programmable Synthesis and Assembly of Amphiphilic Nucleic Acids as an All-in-One Platform for Cation-Free siRNA Delivery

Engineering AND-Gate Aptamer-Signal Base Conjugates for Targeted Magnetic Resonance Molecular Imaging of Metastatic Cancer

(2022) Yazhou Li et al.   ACS Applied Materials & Interfaces

Thymidylate Synthase Overexpression Drives the Invasive Phenotype in Colon Cancer Cells

(2022) Wojciech M. Ciszewski et al.   Biomedicines

A Hitchhiker’s Guide to Click-Chemistry with Nucleic Acids

(2021) Nicolò Zuin Fantoni et al.   CHEMICAL REVIEWS

Constructing an Acidic Microenvironment by MoS 2 in Heterogeneous Fenton Reaction for Pollutant Control

(2021) Qingyun Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells

(2021) Changwon Yang et al.   Redox Biology

Molecularly Engineering Triptolide with Aptamers for High Specificity and Cytotoxicity for Triple-Negative Breast Cancer

(2020) Jiaxuan He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Advances in oligonucleotide drug delivery

(2020) Thomas C. Roberts et al.   NATURE REVIEWS DRUG DISCOVERY

Beyond Blocking: Engineering RNAi-Mediated Targeted Immune Checkpoint Nanoblocker Enables T-Cell-Independent Cancer Treatment

(2020) Xiaoyan Han et al.   ACS Nano

Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery

(2019) Santiago Grijalvo et al.   Pharmaceutics

Engineering of Bioinspired, Size-Controllable, Self-Degradable Cancer-Targeting DNA Nanoflowers via the Incorporation of an Artificial Sandwich Base

(2019) Lili Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The siRNAsome: A Cation-Free and Versatile Nanostructure for siRNA and Drug Co-delivery

(2019) Meng Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two-in-One Chemogene Assembled from Drug-Integrated Antisense Oligonucleotides To Reverse Chemoresistance

(2019) Quanbing Mou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Size-Tunable Assemblies Based on Ferrocene-Containing DNA Polymers for Spatially Uniform Penetration

(2019) Jie Tan et al.   Chem

Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery

(2019) Byungji Kim et al.   ADVANCED MATERIALS

Construction of a Multiple-Aptamer-Based DNA Logic Device on Live Cell Membranes via Associative Toehold Activation for Accurate Cancer Cell Identification

(2019) Xu Chang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembled Double-Bundle DNA Tetrahedron for Efficient Antisense Delivery

(2018) Juanjuan Yang et al.   ACS Applied Materials & Interfaces

Engineering Multifunctional RNAi Nanomedicine To Concurrently Target Cancer Hallmarks for Combinatorial Therapy

(2018) Yanlan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Delivering CRISPR: a review of the challenges and approaches

(2018) Christopher A. Lino et al.   DRUG DELIVERY

Selective in Situ Assembly of Viral Protein onto DNA Origami

(2018) Kun Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of the combined effect of NIR laser and ionizing radiation on cellular damages induced by IUdR-loaded PLGA-coated Nano-graphene oxide

(2018) Samira Kargar et al.   Photodiagnosis and Photodynamic Therapy

Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs

(2018) Owen S. Fenton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thymidylate kinase is critical for DNA repair via ATM-dependent Tip60 complex formation

(2018) Chun-Mei Hu et al.   FASEB JOURNAL

Efficient DNA Condensation by a C 3 ‐Symmetric Codeine Scaffold

(2018) Natasha McStay et al.   ChemPlusChem

Antisense Oligonucleotide-Based Therapy for Neuromuscular Disease

(2017) Valentina Sardone et al.   MOLECULES

Engineering nucleic acid structures for programmable molecular circuitry and intracellular biocomputation

(2017) Jiang Li et al.   Nature Chemistry

Cyclic dipeptide based cell-penetrating peptidomimetics for effective DNA delivery

(2017) Chilakapati Madhu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Applications of CRISPR technologies in research and beyond

(2016) Rodolphe Barrangou et al.   NATURE BIOTECHNOLOGY

C3-symmetric opioid scaffolds are pH-responsive DNA condensation agents

(2016) Natasha McStay et al.   NUCLEIC ACIDS RESEARCH

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Overexpression of thymidylate synthetase confers an independent prognostic indicator in nasopharyngeal carcinoma

(2013) Sung-Wei Lee et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates

(2013) C. H. J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled Translocation of Individual DNA Molecules through Protein Nanopores with Engineered Molecular Brakes

(2011) Marcela Rincon-Restrepo et al.   NANO LETTERS