Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer
出版年份 2016 全文链接
标题
Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 213, Issue 11, Pages 2503-2523
出版商
Rockefeller University Press
发表日期
2016-10-17
DOI
10.1084/jem.20160397
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression
- (2016) Hani Goodarzi et al. CELL
- Why should cancer biologists care about tRNAs? tRNA synthesis, mRNA translation and the control of growth
- (2015) Savraj S. Grewal Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity
- (2015) Danny D. Nedialkova et al. CELL
- A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis
- (2015) Sophie Laguesse et al. DEVELOPMENTAL CELL
- Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine
- (2015) Aurélie Ladang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
- (2015) Xin Ye et al. NATURE
- Elongator, a conserved complex required for wobble uridine modifications in Eukaryotes
- (2015) Tony Karlsborn et al. RNA Biology
- Blockade of Wnt/β-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype
- (2015) Gyu-Beom Jang et al. Scientific Reports
- Metastatic Stem Cells: Sources, Niches, and Vital Pathways
- (2014) Thordur Oskarsson et al. Cell Stem Cell
- Archaeal Elp3 catalyzes tRNA wobble uridine modification at C5 via a radical mechanism
- (2014) Kiruthika Selvadurai et al. Nature Chemical Biology
- The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers
- (2014) L M Privette Vinnedge et al. ONCOGENE
- Hypoxia Induces VEGF-C Expression in Metastatic Tumor Cells via a HIF-1α-Independent Translation-Mediated Mechanism
- (2014) Florent Morfoisse et al. Cell Reports
- A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1
- (2014) B. P. Tsai et al. Open Biology
- Microenvironment and tumor cell plasticity: An easy way out
- (2013) Maria Letizia Taddei et al. CANCER LETTERS
- Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program
- (2013) Kevin J. Cheung et al. CELL
- MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis
- (2013) Junchao Cai et al. JOURNAL OF CLINICAL INVESTIGATION
- Selection and adaptation during metastatic cancer progression
- (2013) Christoph A. Klein NATURE
- Knockdown of Lymphoid Enhancer factor 1 Inhibits Colon Cancer Progression In Vitro and In Vivo
- (2013) Wen-Juan Wang et al. PLoS One
- tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding
- (2013) V. A. N. Rezgui et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ikbkap/Elp1 Deficiency Causes Male Infertility by Disrupting Meiotic Progression
- (2013) Fu-Jung Lin et al. PLoS Genetics
- Modification of tRNALysUUU by Elongator Is Essential for Efficient Translation of Stress mRNAs
- (2013) Jorge Fernández-Vázquez et al. PLoS Genetics
- Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling
- (2013) Boris Zinshteyn et al. PLoS Genetics
- Biosynthesis and Function of Posttranscriptional Modifications of Transfer RNAs
- (2012) Basma El Yacoubi et al. Annual Review of Genetics
- Abstract SY28-02: Interactions between cancer stem cells and their niche govern metastatic colonization
- (2012) I. Malanchi et al. CANCER RESEARCH
- Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion
- (2012) Fang-I Huang et al. CARCINOGENESIS
- DERP6 (ELP5) and C3ORF75 (ELP6) Regulate Tumorigenicity and Migration of Melanoma Cells as Subunits of Elongator
- (2012) Pierre Close et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DEK overexpression is correlated with the clinical features of breast cancer
- (2012) Shuangping Liu et al. PATHOLOGY INTERNATIONAL
- Py2T Murine Breast Cancer Cells, a Versatile Model of TGFβ-Induced EMT In Vitro and In Vivo
- (2012) Lorenz Waldmeier et al. PLoS One
- Translational Control of Cell Division by Elongator
- (2012) Fanelie Bauer et al. Cell Reports
- Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs
- (2011) I. K. Guttilla et al. BREAST CANCER RESEARCH AND TREATMENT
- Tumor Metastasis: Molecular Insights and Evolving Paradigms
- (2011) Scott Valastyan et al. CELL
- A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors
- (2011) Martin Filipits et al. CLINICAL CANCER RESEARCH
- Quantitative Profiling ofIn Vivo-assembled RNA-Protein Complexes Using a Novel Integrated Proteomic Approach
- (2011) Becky Pinjou Tsai et al. MOLECULAR & CELLULAR PROTEOMICS
- La enhances IRES-mediated translation of laminin B1 during malignant epithelial to mesenchymal transition
- (2011) Michaela Petz et al. NUCLEIC ACIDS RESEARCH
- The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer
- (2011) L M Privette Vinnedge et al. ONCOGENE
- GOBO: Gene Expression-Based Outcome for Breast Cancer Online
- (2011) Markus Ringnér et al. PLoS One
- Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding
- (2010) L. Songe-Moller et al. MOLECULAR AND CELLULAR BIOLOGY
- DEK oncoprotein regulates transcriptional modifiers and sustains tumor initiation activity in high-grade neuroendocrine carcinoma of the lung
- (2010) T Shibata et al. ONCOGENE
- Overexpression of the Cellular DEK Protein Promotes Epithelial Transformation In vitro and In vivo
- (2009) T. M. Wise-Draper et al. CANCER RESEARCH
- Melanoma Proliferation and Chemoresistance Controlled by the DEK Oncogene
- (2009) M. S. Khodadoust et al. CANCER RESEARCH
- Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin
- (2009) Catherine Creppe et al. CELL
- WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
- (2009) Don X. Nguyen et al. CELL
- Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
- (2009) Yuliya Pylayeva et al. JOURNAL OF CLINICAL INVESTIGATION
- Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA
- (2009) Sebastian Leidel et al. NATURE
- Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
- (2009) Gabsang Lee et al. NATURE
- tRNA over-expression in breast cancer and functional consequences
- (2009) Mariana Pavon-Eternod et al. NUCLEIC ACIDS RESEARCH
- Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions
- (2009) Akiko Noma et al. NUCLEIC ACIDS RESEARCH
- Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in Caenorhabditis elegans Elongator Mutants
- (2009) Changchun Chen et al. PLoS Genetics
- The Humoral Immune System Has a Key Prognostic Impact in Node-Negative Breast Cancer
- (2008) M. Schmidt et al. CANCER RESEARCH
- TGFβ in Cancer
- (2008) Joan Massagué CELL
- Thio-modification of Yeast Cytosolic tRNA Requires a Ubiquitin-related System That Resembles Bacterial Sulfur Transfer Systems
- (2008) Yumi Nakai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration
- (2008) L. D. Johansen et al. JOURNAL OF CELL SCIENCE
- The conserved Wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity
- (2008) M. Dewez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway
- (2008) C. D. Schlieker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started