tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding

A Role for tRNA Modifications in Genome Structure and Codon Usage

(2012) Eva Maria Novoa et al.   CELL

An integrated image analysis platform to quantify signal transduction in single cells

(2012) Serge Pelet et al.   Integrative Biology

Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications

(2012) Ashish Patil et al.   RNA Biology

Translational Control of Cell Division by Elongator

(2012) Fanelie Bauer et al.   Cell Reports

Human tRNALys3UUU Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto–Enol Tautomerism

(2011) Franck A.P. Vendeix et al.   JOURNAL OF MOLECULAR BIOLOGY

A genome-wide screen identifies yeast genes required for protection against or enhanced cytotoxicity of the antimalarial drug quinine

(2011) Sandra C. dos Santos et al.   MOLECULAR GENETICS AND GENOMICS

A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress

(2010) Clement T. Y. Chan et al.   PLoS Genetics

Normalization and Statistical Analysis of Quantitative Proteomics Data Generated by Metabolic Labeling

(2009) Lily Ting et al.   MOLECULAR & CELLULAR PROTEOMICS

Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA

(2009) Sebastian Leidel et al.   NATURE

Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions

(2009) Akiko Noma et al.   NUCLEIC ACIDS RESEARCH

Coding-Sequence Determinants of Gene Expression in Escherichia coli

(2009) G. Kudla et al.   SCIENCE

Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in Caenorhabditis elegans Elongator Mutants

(2009) Changchun Chen et al.   PLoS Genetics

Thio-modification of Yeast Cytosolic tRNA Requires a Ubiquitin-related System That Resembles Bacterial Sulfur Transfer Systems

(2008) Yumi Nakai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eukaryotic Wobble Uridine Modifications Promote a Functionally Redundant Decoding System

(2008) M. J. O. Johansson et al.   MOLECULAR AND CELLULAR BIOLOGY

Kinetic Checkpoint at a Late Step in Translation Initiation

(2008) Pohl Milon et al.   MOLECULAR CELL

Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

(2008) Lyris M. F. de Godoy et al.   NATURE

MODOMICS: a database of RNA modification pathways. 2008 update

(2008) A. Czerwoniec et al.   NUCLEIC ACIDS RESEARCH

The conserved Wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity

(2008) M. Dewez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway

(2008) C. D. Schlieker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae

(2008) B. Huang et al.   RNA