Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenzaS. aureuspneumonia

The Acute Respiratory Distress Syndrome: From Mechanism to Translation

(2015) SeungHye Han et al.   JOURNAL OF IMMUNOLOGY

Necrostatin-1 Ameliorates Intracerebral Hemorrhage-Induced Brain Injury in Mice Through Inhibiting RIP1/RIP3 Pathway

(2015) Xingfen Su et al.   NEUROCHEMICAL RESEARCH

In the Literature

(2014)   CLINICAL INFECTIOUS DISEASES

Influenza Infection Suppresses NADPH Oxidase-Dependent Phagocytic Bacterial Clearance and Enhances Susceptibility to Secondary Methicillin-Resistant Staphylococcus aureus Infection

(2014) K. Sun et al.   JOURNAL OF IMMUNOLOGY

Vancomycin-Rifampin Combination Therapy Has Enhanced Efficacy against an Experimental Staphylococcus aureus Prosthetic Joint Infection

(2013) Jared A. Niska et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Immune Dysfunction and Bacterial Coinfections following Influenza

(2013) D. W. Metzger et al.   JOURNAL OF IMMUNOLOGY

Influenza A Exacerbates Staphylococcus aureus Pneumonia by Attenuating IL-1  Production in Mice

(2013) K. M. Robinson et al.   JOURNAL OF IMMUNOLOGY

Adjunctive Corticosteroid Therapy Improves Lung Immunopathology and Survival During Severe Secondary Pneumococcal Pneumonia in Mice

(2013) H. E. Ghoneim et al.   JOURNAL OF INFECTIOUS DISEASES

Combination Therapy With Lysin CF-301 and Antibiotic Is Superior to Antibiotic Alone for Treating Methicillin-Resistant Staphylococcus aureus–Induced Murine Bacteremia

(2013) Raymond Schuch et al.   JOURNAL OF INFECTIOUS DISEASES

Pathogenesis of influenza-induced acute respiratory distress syndrome

(2013) Kirsty R Short et al.   LANCET INFECTIOUS DISEASES

The effect of NADPH-oxidase inhibitor apocynin on cognitive impairment induced by moderate lateral fluid percussion injury: Role of inflammatory and oxidative brain damage

(2013) Ana Paula Oliveira Ferreira et al.   NEUROCHEMISTRY INTERNATIONAL

Effect of Linezolid on Clinical Severity and Pulmonary Cytokines in a Murine Model of Influenza A and Staphylococcus aureus Coinfection

(2013) Xinyan Liu et al.   PLoS One

Cell Death from Antibiotics Without the Involvement of Reactive Oxygen Species

(2013) Y. Liu et al.   SCIENCE

Role of Tissue Protection in Lethal Respiratory Viral-Bacterial Coinfection

(2013) A. M. Jamieson et al.   SCIENCE

Apocynin reduces reactive oxygen species concentrations in exhaled breath condensate in asthmatics

(2012) J. Stefanska et al.   EXPERIMENTAL LUNG RESEARCH

The impact of bacterial and viral co-infection in severe influenza

(2012) Christopher C. Blyth et al.   Influenza and Other Respiratory Viruses

Epidemiology, microbiology, and treatment considerations for bacterial pneumonia complicating influenza

(2012) Mark L. Metersky et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Corticosteroid Treatment in Critically Ill Patients with Pandemic Influenza A/H1N1 2009 Infection

(2011) Sung-Han Kim et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Fas Determines Differential Fates of Resident and Recruited Macrophages during Resolution of Acute Lung Injury

(2011) William J Janssen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

In VivoEfficacy of the Novel Aminoglycoside ACHN-490 in Murine Infection Models

(2011) Noe Reyes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Peculiarities of cell death mechanisms in neutrophils

(2011) B Geering et al.   CELL DEATH AND DIFFERENTIATION

Effect of immunomodulatory therapies in patients with pandemic influenza A (H1N1) 2009 complicated by pneumonia

(2011) Diego Viasus et al.   JOURNAL OF INFECTION

Influenza Virus Primes Mice for Pneumonia From Staphylococcus aureus

(2011) Amy R. Iverson et al.   JOURNAL OF INFECTIOUS DISEASES

NADPH-oxidase but not inducible nitric oxide synthase contributes to resistance in a murine Staphylococcus aureus Newman pneumonia model

(2011) Jens Köhler et al.   MICROBES AND INFECTION

Absence of phagocyte NADPH oxidase 2 leads to severe inflammatory response in lungs of mice infected with Coccidioides

(2011) Angel Gonzalez et al.   MICROBIAL PATHOGENESIS

Neutrophil clearance: when the party is over, clean-up begins

(2011) Donna L. Bratton et al.   TRENDS IN IMMUNOLOGY

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

(2011) Ross Vlahos et al.   PLoS Pathogens

Development of selective inhibitors of necrosis

(2010) Mikiko Sodeoka et al.   CHEMICAL RECORD

Oxidative stress as a novel target in pediatric sepsis management

(2010) Bettina von Dessauer et al.   JOURNAL OF CRITICAL CARE

CCR2-Antagonist Prophylaxis Reduces Pulmonary Immune Pathology and Markedly Improves Survival during Influenza Infection

(2010) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung

(2010) Cherrie-Lee Small et al.   JOURNAL OF IMMUNOLOGY

Influenza A Inhibits Th17-Mediated Host Defense against Bacterial Pneumonia in Mice

(2010) A. Kudva et al.   JOURNAL OF IMMUNOLOGY

Bacteria-induced phagocyte secondary necrosis as a pathogenicity mechanism

(2010) Manuel T. Silva   JOURNAL OF LEUKOCYTE BIOLOGY

Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis

(2010) Michael A. Kohanski et al.   MOLECULAR CELL

NADPH Oxidase Limits Innate Immune Responses in the Lungs in Mice

(2010) Brahm H. Segal et al.   PLoS One

Incidence, characteristics and outcomes of patients with severe community acquired-MRSA pneumonia

(2009) K. Z. Vardakas et al.   EUROPEAN RESPIRATORY JOURNAL

TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

(2009) J. R. Aldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models of acute lung injury

(2008) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE