Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion

Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD

(2015) M. Chopra et al.   BLOOD

Donor Requirements for Regulatory T Cell Suppression of Murine Graft-versus-Host Disease

(2015) Antonio Pierini et al.   JOURNAL OF IMMUNOLOGY

Transmembrane TNF–TNFR2 Impairs Th17 Differentiation by PromotingIl2Expression

(2015) Patrick G. Miller et al.   JOURNAL OF IMMUNOLOGY

CD4+ invariant natural killer T cells protect from murine GVHD lethality through expansion of donor CD4+CD25+FoxP3+ regulatory T cells

(2014) D. Schneidawind et al.   BLOOD

HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse

(2014) M. F. Martelli et al.   BLOOD

Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells

(2014) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells and natural killer T cells for modulation of GVHD following allogeneic hematopoietic cell transplantation

(2013) D. Schneidawind et al.   BLOOD

Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease

(2013) A. Veerapathran et al.   BLOOD

Tumor necrosis factor receptor 2-dependent homeostasis of regulatory T cells as a player in TNF-induced experimental metastasis

(2013) Martin Chopra et al.   CARCINOGENESIS

TNFR2 Is Critical for the Stabilization of the CD4+Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment

(2013) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

(2013) Hong Nie et al.   NATURE MEDICINE

Non-Invasive Bioluminescence Imaging to Monitor the Immunological Control of a Plasmablastic Lymphoma-Like B Cell Neoplasia after Hematopoietic Cell Transplantation

(2013) Martin Chopra et al.   PLoS One

Homogeneous Expansion of Human T-Regulatory Cells Via Tumor Necrosis Factor Receptor 2

(2013) Yoshiaki Okubo et al.   Scientific Reports

TNF-α impairs differentiation and function of TGF-β-induced Treg cells in autoimmune diseases through Akt and Smad3 signaling pathway

(2012) Qi Zhang et al.   Journal of Molecular Cell Biology

Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412

(2011) P. S. Romer et al.   BLOOD

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Regulatory T cells in stem cell transplantation: strategies and first clinical experiences

(2011) Matthias Edinger et al.   CURRENT OPINION IN IMMUNOLOGY

TNFR2 on non-haematopoietic cells is required for Foxp3+Treg-cell function and disease suppression in EAE

(2011) Niki Tsakiri et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Implications of TNF-α in the pathogenesis and management of GVHD

(2011) John E. Levine   INTERNATIONAL JOURNAL OF HEMATOLOGY

Natural but Not Inducible Regulatory T Cells Require TNF-  Signaling for In Vivo Function

(2011) W. J. Housley et al.   JOURNAL OF IMMUNOLOGY

Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells

(2010) J. M. Coghill et al.   BLOOD

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Selective Depletion of Foxp3+ Regulatory T Cells Improves Effective Therapeutic Vaccination against Established Melanoma

(2010) K. Klages et al.   CANCER RESEARCH

Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+regulatory T cells in human peripheral blood

(2010) Xin Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs

(2010) Yenkel Grinberg-Bleyer et al.   JOURNAL OF CLINICAL INVESTIGATION

A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice

(2010) N. Casares et al.   JOURNAL OF IMMUNOLOGY

TNF Activates a NF- B-Regulated Cellular Program in Human CD45RA- Regulatory T Cells that Modulates Their Suppressive Function

(2010) M. Nagar et al.   JOURNAL OF IMMUNOLOGY

Expression of Costimulatory TNFR2 Induces Resistance of CD4+FoxP3- Conventional T Cells to Suppression by CD4+FoxP3+ Regulatory T Cells

(2010) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells Support Homeostatic Expansion of Foxp3 + Regulatory T Cells in Foxp3.LuciDTR Mice

(2010) Janine Suffner et al.   JOURNAL OF IMMUNOLOGY

Membrane Tumor Necrosis Factor (TNF) Induces p100 Processing via TNF Receptor-2 (TNFR2)

(2009) Hilka Rauert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoimmune diseases induced by TNF-targeted therapies

(2008) Manuel Ramos-Casals et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Induction and exacerbation of psoriasis with TNF-blockade therapy: A review and analysis of 127 cases

(2008) Justin M. Ko et al.   JOURNAL OF DERMATOLOGICAL TREATMENT