Multivalent interactions with RNA drive recruitment and dynamics in biomolecular condensates in Xenopus oocytes

Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development

(2022) Mainak Bose et al.   CELL

In vivo reconstitution finds multivalent RNA-RNA interactions as drivers of mesh-like condensates

(2021) Weirui Ma et al.   eLife

Higher-order organization of biomolecular condensates

(2021) Charlotte M. Fare et al.   Open Biology

L-bodies are RNA–protein condensates driving RNA localization in Xenopus oocytes

(2021) Christopher R. Neil et al.   MOLECULAR BIOLOGY OF THE CELL

FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells

(2020) Jean A. Smith et al.   JOURNAL OF CELL BIOLOGY

Sequence-Independent Self-Assembly of Germ Granule mRNAs into Homotypic Clusters

(2020) Tatjana Trcek et al.   MOLECULAR CELL

Dynamic metastable long-living droplets formed by sticker-spacer proteins

(2020) Srivastav Ranganathan et al.   eLife

Protein condensates as aging Maxwell fluids

(2020) Louise Jawerth et al.   SCIENCE

A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos

(2019) Andrea Putnam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Stochastic Seeding Coupled with mRNA Self-Recruitment Generates Heterogeneous Drosophila Germ Granules

(2018) Matthew G. Niepielko et al.   CURRENT BIOLOGY

The Role of RNA in Biological Phase Separations

(2018) Marta M. Fay et al.   JOURNAL OF MOLECULAR BIOLOGY

RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome

(2018) Briana Van Treeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

mRNA structure determines specificity of a polyQ-driven phase separation

(2018) Erin M. Langdon et al.   SCIENCE

Protein Phase Separation: A New Phase in Cell Biology

(2018) Steven Boeynaems et al.   TRENDS IN CELL BIOLOGY

Emerging Roles for Intermolecular RNA-RNA Interactions in RNP Assemblies

(2018) Briana Van Treeck et al.   CELL

Multiple Modes of Protein–Protein Interactions Promote RNP Granule Assembly

(2018) Tanja Mittag et al.   JOURNAL OF MOLECULAR BIOLOGY

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions

(2018) Weirui Ma et al.   CELL

RNA phase transitions in repeat expansion disorders

(2017) Ankur Jain et al.   NATURE

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Amyloid-like Self-Assembly of a Cellular Compartment

(2016) Elvan Boke et al.   CELL

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Using in vivo imaging to measure RNA mobility in Xenopus laevis oocytes

(2016) Erin A. Powrie et al.   METHODS

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

(2015) Kathleen A. Burke et al.   MOLECULAR CELL

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Directional Transport Is Mediated by a Dynein-Dependent Step in an RNA Localization Pathway

(2013) James A. Gagnon et al.   PLOS BIOLOGY

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Activation of picornaviral IRESs by PTB shows differential dependence on each PTB RNA-binding domain

(2011) P. Kafasla et al.   RNA

Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs

(2010) Yuntao S. Mao et al.   NATURE CELL BIOLOGY

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Multiple Kinesin Motors Coordinate Cytoplasmic RNA Transport on a Subpopulation of Microtubules in Xenopus Oocytes

(2008) Timothy J. Messitt et al.   DEVELOPMENTAL CELL