Ligand-independent integrin β1 signaling supports lung adenocarcinoma development

Structural basis of Focal Adhesion Kinase activation on lipid membranes

(2020) Iván Acebrón et al.   EMBO JOURNAL

Targeting focal adhesion kinase in cancer cells and the tumor microenvironment

(2020) James M. Murphy et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis

(2020) Veronika Ramovs et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Increased Expression and Activation of FAK in Small-Cell Lung Cancer Compared to Non-Small-Cell Lung Cancer

(2019) Frank Aboubakar Nana et al.   Cancers

The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma

(2017) Shuo Chen et al.   Cell Death & Disease

Elucidation of the Roles of Tumor Integrin  1 in the Extravasation Stage of the Metastasis Cascade

(2016) M. B. Chen et al.   CANCER RESEARCH

Integrin and gene network analysis reveals that ITGA5 and ITGB1 are prognostic in non-small-cell lung cancer

(2016) Weiqi Zheng et al.   OncoTargets and Therapy

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

(2016) Marina Theodosiou et al.   eLife

Integrin endosomal signalling suppresses anoikis

(2015) Jonna Alanko et al.   NATURE CELL BIOLOGY

Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance

(2015) Laetitia Seguin et al.   TRENDS IN CELL BIOLOGY

Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients withKRASwild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial

(2014) E. Élez et al.   ANNALS OF ONCOLOGY

The Integrin β1 Subunit Regulates Paracellular Permeability of Kidney Proximal Tubule Cells

(2014) Bertha C. Elias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

(2014) Roger Stupp et al.   LANCET ONCOLOGY

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

An integrin β3–KRAS–RalB complex drives tumour stemness and resistance to EGFR inhibition

(2014) Laetitia Seguin et al.   NATURE CELL BIOLOGY

β1 Integrins with Individually Disrupted Cytoplasmic NPxY Motifs Are Embryonic Lethal but Partially Active in the Epidermis

(2013) Alexander Meves et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of integrin β1 as a prognostic biomarker for human lung adenocarcinoma using 2D-LC-MS/MS combined with iTRAQ technology

(2013) PENG-FEI ZHANG et al.   ONCOLOGY REPORTS

Integrative Analyses Identify Osteopontin, LAMB3 and ITGB1 as Critical Pro-Metastatic Genes for Lung Cancer

(2013) Xiao-Min Wang et al.   PLoS One

RHOA-FAK Is a Required Signaling Axis for the Maintenance of KRAS-Driven Lung Adenocarcinomas

(2013) Georgia Konstantinidou et al.   Cancer Discovery

Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression

(2012) Ssang-Taek Lim et al.   JOURNAL OF CELL BIOLOGY

 1 Integrin NPXY Motifs Regulate Kidney Collecting-Duct Development and Maintenance by Induced-Fit Interactions with Cytosolic Proteins

(2012) S. Mathew et al.   MOLECULAR AND CELLULAR BIOLOGY

Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma

(2012) X. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model

(2012) Kim Moran-Jones et al.   Scientific Reports

β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells

(2011) V Morello et al.   ONCOGENE

 1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation

(2011) A. Meves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin expression profiling identifies integrin alpha5 and beta1 as prognostic factors in early stage non-small cell lung cancer

(2010) Anne-Marie C Dingemans et al.   Molecular Cancer

An Activating β1 Integrin Mutation Increases the Conversion of Benign to Malignant Skin Tumors

(2009) Manuela Ferreira et al.   CANCER RESEARCH

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

Tac-β1 inhibits FAK activation and Src signaling

(2008) Allison L. Berrier et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of Integrin  1 1 Ameliorates Kras-Induced Lung Cancer

(2008) I. Macias-Perez et al.   CANCER RESEARCH

Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation

(2008) Ssang-Taek Lim et al.   MOLECULAR CELL

Focal Adhesion Kinase Versus p53: Apoptosis or Survival?

(2008) W. G. Cance et al.   Science Signaling