Recent Advances in Improving Gene-Editing Specificity through CRISPR–Cas9 Nuclease Engineering
出版年份 2022 全文链接
标题
Recent Advances in Improving Gene-Editing Specificity through CRISPR–Cas9 Nuclease Engineering
作者
关键词
-
出版物
Cells
Volume 11, Issue 14, Pages 2186
出版商
MDPI AG
发表日期
2022-07-14
DOI
10.3390/cells11142186
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
- (2022) Samagya Banskota et al. CELL
- Two high-fidelity variants: efSaCas9 and SaCas9-HF, which one is better?
- (2022) Jineng Lv et al. GENE THERAPY
- The use of new CRISPR tools in cardiovascular research and medicine
- (2022) Masataka Nishiga et al. Nature Reviews Cardiology
- Structural basis for mismatch surveillance by CRISPR–Cas9
- (2022) Jack P. K. Bravo et al. NATURE
- Antispacer peptide nucleic acids for sequence-specific CRISPR-Cas9 modulation
- (2022) Nicholas G Economos et al. NUCLEIC ACIDS RESEARCH
- FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity
- (2022) Zifeng Cui et al. Nature Communications
- Simultaneous knockout of multiple LHCF genes using single sgRNAs and engineering of a high‐fidelity Cas9 for precise genome editing in marine algae
- (2021) Amit K. Sharma et al. PLANT BIOTECHNOLOGY JOURNAL
- Lentiviral Capsid-Mediated Streptococcus pyogenes Cas9 Ribonucleoprotein Delivery for Efficient and Safe Multiplex Genome Editing
- (2021) Zuyan Lu et al. CRISPR Journal
- Engineered pegRNAs improve prime editing efficiency
- (2021) James W. Nelson et al. NATURE BIOTECHNOLOGY
- High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination
- (2021) Chaya T L Yuen et al. NUCLEIC ACIDS RESEARCH
- Peptide nucleic acid–dependent artifact can lead to false-positive triplex gene editing signals
- (2021) Pui Yan Ho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair
- (2020) Nicholas G. Economos et al. MOLECULES
- Comparison of CRISPR-Cas9/Cas12a Ribonucleoprotein Complexes for Genome Editing Efficiency in the Rice Phytoene Desaturase (OsPDS) Gene
- (2020) Raviraj Banakar et al. Rice
- CRISPR/Cas Systems in Genome Editing: Methodologies and Tools for sgRNA Design, Off‐Target Evaluation, and Strategies to Mitigate Off‐Target Effects
- (2020) Hakim Manghwar et al. Advanced Science
- Highly Parallel Profiling of Cas9 Variant Specificity
- (2020) Jonathan L. Schmid-Burgk et al. MOLECULAR CELL
- An engineered ScCas9 with broad PAM range and high specificity and activity
- (2020) Pranam Chatterjee et al. NATURE BIOTECHNOLOGY
- Machine learning predicts new anti-CRISPR proteins
- (2020) Simon Eitzinger et al. NUCLEIC ACIDS RESEARCH
- SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity
- (2020) Derek Cerchione et al. PLoS One
- Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants
- (2020) Russell T. Walton et al. SCIENCE
- A Cas9 with PAM recognition for adenine dinucleotides
- (2020) Pranam Chatterjee et al. Nature Communications
- A compact Cas9 ortholog from Staphylococcus Auricularis (SauriCas9) expands the DNA targeting scope
- (2020) Ziying Hu et al. PLOS BIOLOGY
- CRISPR system: Discovery, development and off-target detection
- (2020) Shengmiao Chen et al. CELLULAR SIGNALLING
- CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
- (2020) Ibrahim C. Kurt et al. NATURE BIOTECHNOLOGY
- Prediction of the sequence-specific cleavage activity of Cas9 variants
- (2020) Nahye Kim et al. NATURE BIOTECHNOLOGY
- High-fidelity SaCas9 identified by directional screening in human cells
- (2020) Haihua Xie et al. PLOS BIOLOGY
- Latest Developed Strategies to Minimize the Off-Target Effects in CRISPR-Cas-Mediated Genome Editing
- (2020) Muhammad Naeem et al. Cells
- MiCas9 increases large size gene knock-in rates and reduces undesirable on-target and off-target indel edits
- (2020) Linyuan Ma et al. Nature Communications
- Virus-Like Particle Mediated CRISPR/Cas9 Delivery for Efficient and Safe Genome Editing
- (2020) Pin Lyu et al. Life-Basel
- Engineer chimeric Cas9 to expand PAM recognition based on evolutionary information
- (2019) Dacheng Ma et al. Nature Communications
- Improving plant genome editing with high-fidelity xCas9 and non-canonical PAM-targeting Cas9-NG
- (2019) Zhaohui Zhong et al. Molecular Plant
- Combined Computational-Experimental Approach to Explore Molecular Mechanism of SaCas9 with Broadened DNA Targeting Range
- (2019) Binquan Luan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Efficient Human Genome Editing Using SaCas9 Ribonucleoprotein Complexes
- (2019) Yufei Wang et al. Biotechnology Journal
- Efficient disruption of bcr-abl gene by CRISPR RNA-guided FokI nucleases depresses the oncogenesis of chronic myeloid leukemia cells
- (2019) Zhenhong Luo et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Delivering Cas9/sgRNA ribonucleoprotein (RNP) by lentiviral capsid-based bionanoparticles for efficient ‘hit-and-run’ genome editing
- (2019) Pin Lyu et al. NUCLEIC ACIDS RESEARCH
- Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity
- (2019) Yuanyan Tan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Improved double-nicking strategies for COL7A1 editing by homologous recombination
- (2019) Thomas Kocher et al. Molecular Therapy-Nucleic Acids
- Multiplex nucleotide editing by high-fidelity Cas9 variants with improved efficiency in rice
- (2019) Wen Xu et al. BMC PLANT BIOLOGY
- Advances in Detecting and Reducing Off-target Effects Generated by CRISPR-mediated Genome Editing
- (2019) Jin-Jing Li et al. Journal of Genetics and Genomics
- Search-and-replace genome editing without double-strand breaks or donor DNA
- (2019) Andrew V. Anzalone et al. NATURE
- Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning
- (2019) Daqi Wang et al. Nature Communications
- SaCas9 Requires 5′-NNGRRT-3′ PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells
- (2018) Haihua Xie et al. Biotechnology Journal
- History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology
- (2018) Yoshizumi Ishino et al. JOURNAL OF BACTERIOLOGY
- A highly specific SpCas9 variant is identified by in vivo screening in yeast
- (2018) Antonio Casini et al. NATURE BIOTECHNOLOGY
- Genotyping genome-edited mutations in plants using CRISPR ribonucleoprotein complexes
- (2018) Zhen Liang et al. PLANT BIOTECHNOLOGY JOURNAL
- Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity
- (2018) Christopher R. Cromwell et al. Nature Communications
- SaCas9 Requires 5′-NNGRRT-3′ PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells
- (2018) Haihua Xie et al. Biotechnology Journal
- Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
- (2018) Johnny H. Hu et al. NATURE
- A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
- (2018) Christopher A. Vakulskas et al. NATURE MEDICINE
- Engineered CRISPR-Cas9 nuclease with expanded targeting space
- (2018) Hiroshi Nishimasu et al. SCIENCE
- Directed evolution of CRISPR-Cas9 to increase its specificity
- (2018) Jungjoon K. Lee et al. Nature Communications
- xC as9 expands the scope of genome editing with reduced efficiency in rice
- (2018) Junjie Wang et al. PLANT BIOTECHNOLOGY JOURNAL
- Orthogonal Cas9–Cas9 chimeras provide a versatile platform for genome editing
- (2018) Mehmet Fatih Bolukbasi et al. Nature Communications
- Minimal PAM specificity of a highly similar SpCas9 ortholog
- (2018) Pranam Chatterjee et al. Science Advances
- Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
- (2017) Janice S. Chen et al. NATURE
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
- (2017) Eunji Kim et al. Nature Communications
- Hit and go CAS9 delivered through a lentiviral based self-limiting circuit
- (2017) Gianluca Petris et al. Nature Communications
- Structural insights into DNA cleavage activation of CRISPR-Cas9 system
- (2017) Cong Huai et al. Nature Communications
- Disabling Cas9 by an anti-CRISPR DNA mimic
- (2017) Jiyung Shin et al. Science Advances
- Structure and Engineering of Francisella novicida Cas9
- (2016) Hisato Hirano et al. CELL
- Naturally Occurring Off-Switches for CRISPR-Cas9
- (2016) April Pawluk et al. CELL
- Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq
- (2016) Daesik Kim et al. GENOME RESEARCH
- Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome
- (2016) Maximilian Müller et al. MOLECULAR THERAPY
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
- (2016) Benjamin P. Kleinstiver et al. NATURE
- Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- (2016) Hao Yin et al. NATURE BIOTECHNOLOGY
- Precision Targeted Mutagenesis via Cas9 Paired Nickases in Rice
- (2016) Masafumi Mikami et al. PLANT AND CELL PHYSIOLOGY
- Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
- (2016) F. Jiang et al. SCIENCE
- Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing
- (2016) Yuichiro Miyaoka et al. Scientific Reports
- Crystal Structure of Staphylococcus aureus Cas9
- (2015) Hiroshi Nishimasu et al. CELL
- Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing
- (2015) Nicolas Wyvekens et al. HUMAN GENE THERAPY
- Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9
- (2015) Taeyoung Koo et al. MOLECULES AND CELLS
- CRISPR-Cas immunity in prokaryotes
- (2015) Luciano A. Marraffini NATURE
- Engineered CRISPR-Cas9 nucleases with altered PAM specificities
- (2015) Benjamin P. Kleinstiver et al. NATURE
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
- (2015) Benjamin P Kleinstiver et al. NATURE BIOTECHNOLOGY
- A split-Cas9 architecture for inducible genome editing and transcription modulation
- (2015) Bernd Zetsche et al. NATURE BIOTECHNOLOGY
- DNA-binding-domain fusions enhance the targeting range and precision of Cas9
- (2015) Mehmet Fatih Bolukbasi et al. NATURE METHODS
- CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo
- (2015) Miguel A Moreno-Mateos et al. NATURE METHODS
- Targeted gene editing by transfection ofin vitroreconstitutedStreptococcus thermophilusCas9 nuclease complex
- (2015) Monika Glemzaite et al. RNA Biology
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- Generation of mutant mice via the CRISPR/Cas9 system using FokI-dCas9
- (2015) Satoshi Hara et al. Scientific Reports
- Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
- (2015) Xiao-Hui Zhang et al. Molecular Therapy-Nucleic Acids
- Genome Editing in Mouse Spermatogonial Stem Cell Lines Using TALEN and Double-Nicking CRISPR/Cas9
- (2015) Takuya Sato et al. Stem Cell Reports
- Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
- (2014) Hiroshi Nishimasu et al. CELL
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Genome-wide identification of CRISPR/Cas9 off-targets in human genome
- (2014) Jinzhi Duan et al. CELL RESEARCH
- Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
- (2014) S. Ramakrishna et al. GENOME RESEARCH
- Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
- (2014) S. Kim et al. GENOME RESEARCH
- Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
- (2014) Carolin Anders et al. NATURE
- Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
- (2014) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
- (2013) Vikram Pattanayak et al. NATURE BIOTECHNOLOGY
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Cas9 as a versatile tool for engineering biology
- (2013) Prashant Mali et al. NATURE METHODS
- Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
- (2013) Z. Hou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
- (2010) Josiane E. Garneau et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now