标题
Lactate: The Mediator of Metabolism and Immunosuppression
作者
关键词
-
出版物
Frontiers in Endocrinology
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2022-06-09
DOI
10.3389/fendo.2022.901495
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cell-programmed nutrient partitioning in the tumour microenvironment
- (2021) Bradley I. Reinfeld et al. NATURE
- Lactate and IL6 define separable paths of inflammatory metabolic adaptation
- (2021) Stefanie Dichtl et al. Science Advances
- Enhanced glucose metabolism mediated by CD147 contributes to immunosuppression in hepatocellular carcinoma
- (2020) Xiaofeng Li et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Integrated analyses identify miR‐34c‐3p/MAGI3 axis for the Warburg metabolism in hepatocellular carcinoma
- (2020) Qiaoyou Weng et al. FASEB JOURNAL
- LncRNA HOTAIR knockdown inhibits glycolysis by regulating miR-130a-3p/HIF1A in hepatocellular carcinoma under hypoxia
- (2020) Mingxing Hu et al. BIOMEDICINE & PHARMACOTHERAPY
- Metabolic Traits in Cutaneous Melanoma
- (2020) Monica Neagu Frontiers in Oncology
- ALKBH5 regulates anti–PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment
- (2020) Na Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lactate-Modulated Immunosuppression of Myeloid-Derived Suppressor Cells Contributes to the Radioresistance of Pancreatic Cancer
- (2020) Xuguang Yang et al. Cancer Immunology Research
- Oncometabolites lactate and succinate drive pro-angiogenic macrophage response in tumors
- (2020) Marjolein M.G. Kes et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Lactic acidosis due to repressed lactate dehydrogenase subunit B expression down-regulates mitochondrial oxidative phosphorylation via the PDK/PDH axis
- (2019) Sun Mi Hong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Blocking TREM-1+ Tumor-associated macrophages induced by hypoxia reverses immunosuppression and anti-PD-L1 resistance in liver cancer
- (2019) Qinchuan Wu et al. HEPATOLOGY
- Lamc1 promotes the Warburg effect in hepatocellular carcinoma cells by regulating PKM2 expression through AKT pathway
- (2019) GuanXiong Ye et al. CANCER BIOLOGY & THERAPY
- Epigenetic control of Foxp3 in intratumoral T-cells regulates growth of hepatocellular carcinoma
- (2019) Qin Liu et al. Aging-US
- RIP 3 deficiency recruits myeloid‐derived suppressor cells to hepatocellular carcinoma through the CXCL 1‐ CXCR 2 axis
- (2019) Yi‐Ming Li et al. HEPATOLOGY
- PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma
- (2019) Jiao Feng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging
- (2019) Antero Salminen et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid
- (2019) Tae-Wook Chung et al. Cancers
- Hepatic Tumor Microenvironments and Effects on NK Cell Phenotype and Function
- (2019) Julián Piñeiro Fernández et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tumor-derived exosomes, myeloid-derived suppressor cells, and tumor microenvironment
- (2019) Xinyu Tian et al. Journal of Hematology & Oncology
- miR-455-5p suppresses hepatocellular carcinoma cell growth and invasion via IGF-1R/AKT/GLUT1 pathway by targeting IGF-1R
- (2019) Yiren Hu et al. PATHOLOGY RESEARCH AND PRACTICE
- Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma
- (2019) Yaping Xu et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Targeted inhibition of MCT4 disrupts intracellular pH homeostasis and confers self-regulated apoptosis on hepatocellular carcinoma
- (2019) Youbo Zhao et al. EXPERIMENTAL CELL RESEARCH
- Metabolic regulation of gene expression by histone lactylation
- (2019) Di Zhang et al. NATURE
- Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion
- (2019) Robert D. Leone et al. SCIENCE
- miR-142-3p inhibits aerobic glycolysis and cell proliferation in hepatocellular carcinoma via targeting LDHA
- (2018) Shengni Hua et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Functional Classification and Experimental Dissection of Long Noncoding RNAs
- (2018) Florian Kopp et al. CELL
- Antitumor T-cell Reconditioning: Improving Metabolic Fitness for Optimal Cancer Immunotherapy
- (2018) Dayana B. Rivadeneira et al. CLINICAL CANCER RESEARCH
- Myeloid-derived suppressor cells coming of age
- (2018) Filippo Veglia et al. NATURE IMMUNOLOGY
- Targeting MCT4 to reduce lactic acid secretion and glycolysis for treatment of neuroendocrine prostate cancer
- (2018) Stephen Yiu Chuen Choi et al. Cancer Medicine
- Caveolin enhances hepatocellular carcinoma cell metabolism, migration, and invasion in vitro via a hexokinase 2-dependent mechanism
- (2018) Fang Chai et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α–mediated tumor progression
- (2018) Na Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Aberrant Metabolism in Hepatocellular Carcinoma Provides Diagnostic and Therapeutic Opportunities
- (2018) Serena De Matteis et al. Oxidative Medicine and Cellular Longevity
- Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy
- (2018) Yangbo Feng et al. Cancer Medicine
- Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway
- (2018) Binghua Li et al. EBioMedicine
- Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
- (2017) Madhav Kishore et al. IMMUNITY
- Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling
- (2017) Shibo Wei et al. ONCOLOGY REPORTS
- Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
- (2017) David Kung-Chun Chiu et al. Nature Communications
- The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinoma
- (2017) Fangfang Jin et al. Scientific Reports
- Lactate Wreaks Havoc on Tumor-Infiltrating T and NK Cells
- (2016) Kristen E.N. Scott et al. Cell Metabolism
- LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
- (2016) Almut Brand et al. Cell Metabolism
- The MCT4 Gene: A Novel, Potential Target for Therapy of Advanced Prostate Cancer
- (2016) S. Y. C. Choi et al. CLINICAL CANCER RESEARCH
- Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26
- (2016) David Kung-Chun Chiu et al. HEPATOLOGY
- CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation
- (2016) Vinit Kumar et al. IMMUNITY
- Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
- (2016) Valerie A Gerriets et al. NATURE IMMUNOLOGY
- Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells
- (2016) Y Deng et al. ONCOGENE
- Activated hepatic stellate cells promote liver cancer by induction of myeloid-derived suppressor cells through cyclooxygenase-2
- (2016) Yaping Xu et al. Oncotarget
- Metabolic reprogramming in macrophages and dendritic cells in innate immunity
- (2015) Beth Kelly et al. CELL RESEARCH
- MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer
- (2015) Weijie Guo et al. HEPATOLOGY
- Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
- (2015) Yan Xiang et al. JOURNAL OF CLINICAL INVESTIGATION
- MicroRNA-9 Regulates the Differentiation and Function of Myeloid-Derived Suppressor Cells via Targeting Runx1
- (2015) Jie Tian et al. JOURNAL OF IMMUNOLOGY
- PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma
- (2015) Wei-Ren Liu et al. Oncotarget
- Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression
- (2014) Patrizia Sanità et al. BMC CANCER
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
- (2014) L. Yang et al. Molecular Systems Biology
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma
- (2014) Angela M. Liu et al. PLoS One
- Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
- (2014) Meera Rath et al. Frontiers in Immunology
- Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer
- (2013) Krushna C. Patra et al. CANCER CELL
- Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
- (2013) Z. Husain et al. JOURNAL OF IMMUNOLOGY
- The SLC2 (GLUT) family of membrane transporters
- (2013) Mike Mueckler et al. MOLECULAR ASPECTS OF MEDICINE
- Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma
- (2012) Shi L. Sheng et al. FEBS Journal
- Myeloid-derived Suppressor Cells (MDSCs) in Gliomas and Glioma-Development
- (2012) Gary Kohanbash et al. IMMUNOLOGICAL INVESTIGATIONS
- Macrophage plasticity and polarization: in vivo veritas
- (2012) Antonio Sica et al. JOURNAL OF CLINICAL INVESTIGATION
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
- (2010) Cesar A. Corzo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes Tumorigenesis
- (2009) Thomas Amann et al. AMERICAN JOURNAL OF PATHOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started