Human umbilical cord-derived mesenchymal stem cells not only ameliorate blood glucose but also protect vascular endothelium from diabetic damage through a paracrine mechanism mediated by MAPK/ERK signaling
出版年份 2022 全文链接
标题
Human umbilical cord-derived mesenchymal stem cells not only ameliorate blood glucose but also protect vascular endothelium from diabetic damage through a paracrine mechanism mediated by MAPK/ERK signaling
作者
关键词
-
出版物
Stem Cell Research & Therapy
Volume 13, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-06-17
DOI
10.1186/s13287-022-02927-8
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation
- (2021) Limin Wu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- MicroRNA-133a Regulates the Viability and Differentiation Fate of Bone Marrow Mesenchymal Stem Cells via MAPK/ERK Signaling Pathway by Targeting FGFR1
- (2021) Gang Wang et al. DNA AND CELL BIOLOGY
- Genetics of diabetes mellitus and diabetes complications
- (2020) Joanne B. Cole et al. Nature Reviews Nephrology
- Potential therapeutic effects of endothelial cells trans-differentiated from Wharton’s Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model
- (2020) Shaimaa M. Motawea et al. Diabetology & Metabolic Syndrome
- METTL1 limits differentiation and functioning of EPCs derived from human-induced pluripotent stem cells through a MAPK/ERK pathway
- (2020) Yujie Deng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cotransplantation of human umbilical cord mesenchymal stem cells and endothelial cells for angiogenesis and pulp regeneration in vivo
- (2020) Shuang Zhang et al. LIFE SCIENCES
- Endothelial Dysfunction in Diabetic Retinopathy
- (2020) Fu Gui et al. Frontiers in Endocrinology
- Arterialization requires the timely suppression of cell growth
- (2020) Wen Luo et al. NATURE
- Stem cells: past, present, and future
- (2019) Wojciech Zakrzewski et al. Stem Cell Research & Therapy
- Human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation improves ovarian function in rats with premature ovarian insufficiency (POI) at least partly through a paracrine mechanism
- (2019) Li Ling et al. Stem Cell Research & Therapy
- Diabetes Impairs Angiogenesis and Induces Endothelial Cell Senescence by Up-Regulating Thrombospondin-CD47-Dependent Signaling
- (2019) Milad Bitar INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mesenchymal Stem Cell Migration and Tissue Repair
- (2019) Fu et al. Cells
- Traditional two-dimensional mesenchymal stem cells (MSCs) are better than spheroid MSCs on promoting retinal ganglion cells survival and axon regeneration
- (2019) Wei Huang et al. EXPERIMENTAL EYE RESEARCH
- Epigenetic regulation in diabetic vascular complications
- (2019) Jiayu Jin et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Menstrual blood-derived stem cells: toward therapeutic mechanisms, novel strategies, and future perspectives in the treatment of diseases
- (2019) Lijun Chen et al. Stem Cell Research & Therapy
- Vascular endothelial growth factor over-expressed mesenchymal stem cells-conditioned media ameliorate palmitate-induced diabetic endothelial dysfunction through PI-3K/AKT/m-TOR/eNOS and p38/MAPK signaling pathway
- (2018) Tianwei Xu et al. BIOMEDICINE & PHARMACOTHERAPY
- Mesenchymal stromal/stem cells as potential therapy in diabetic retinopathy
- (2018) Agnese Fiori et al. IMMUNOBIOLOGY
- Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications
- (2018) Bou-Yue Peng et al. Journal of Diabetes Research
- Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy
- (2018) Wuzheng Zhu et al. Cell Death & Disease
- Downregulation of long noncoding RNA HOTAIRM1 variant 1 contributes to osteoarthritis via regulating miR-125b/BMPR2 axis and activating JNK/MAPK/ERK pathway
- (2018) Yu Xiao et al. BIOMEDICINE & PHARMACOTHERAPY
- Nano-medicine and Vascular Endothelial Dysfunction: Options and Delivery Strategies
- (2018) Gaurav Taneja et al. Cardiovascular Toxicology
- Overexpression of ERBB4 rejuvenates aged mesenchymal stem cell and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathway
- (2018) Xiaoting Liang et al. FASEB JOURNAL
- Regulation of fibroblast growth factor 8 (FGF8 ) in chicken embryonic stem cells differentiation into spermatogonial stem cells
- (2017) Man Wang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Macro- and microvascular endothelial dysfunction in diabetes
- (2017) Yi Shi et al. Journal of Diabetes
- Vascular Complications of Diabetes
- (2016) Joshua A. Beckman et al. CIRCULATION RESEARCH
- Mesenchymal stem cell-conditioned media ameliorate diabetic endothelial dysfunction by improving mitochondrial bioenergetics via the Sirt1/AMPK/PGC-1 pathway
- (2016) Y. Yuan et al. CLINICAL SCIENCE
- Diabetic nephropathy and endothelial dysfunction: Current and future therapies, and emerging of vascular imaging for preclinical renal-kinetic study
- (2016) Wilson KC Leung et al. LIFE SCIENCES
- miR-148a-3p represses proliferation and EMT by establishing regulatory circuits between ERBB3/AKT2/c-myc and DNMT1 in bladder cancer
- (2016) Xiao Wang et al. Cell Death & Disease
- C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1α via CD64/PI3k/Akt and MAPK/ERK signaling pathways
- (2016) JiaYuan Chen et al. Stem Cell Research & Therapy
- Fabrication of hydroxyapatite/chitosan composite hydrogels loaded with exosomes derived from miR-126-3p overexpressed synovial mesenchymal stem cells for diabetic chronic wound healing
- (2016) Min Li et al. Journal of Materials Chemistry B
- Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes
- (2016) Kanna Nagaishi et al. Scientific Reports
- TGF-β3 and IGF-1 synergy ameliorates nucleus pulposus mesenchymal stem cell differentiation towards the nucleus pulposus cell type through MAPK/ERK signaling
- (2015) Yiqing Tao et al. GROWTH FACTORS
- Human mesenchymal stem cells enhance cancer cell proliferation via IL-6 secretion and activation of ERK1/2
- (2015) AGMAL SCHERZAD et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis
- (2015) Yu Sun et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Adipose-derived mesenchymal stem cells improve glucose homeostasis in high-fat diet-induced obese mice
- (2015) Mingjun Cao et al. Stem Cell Research & Therapy
- Hypoxia Pretreatment of Bone Marrow Mesenchymal Stem Cells Facilitates Angiogenesis by Improving the Function of Endothelial Cells in Diabetic Rats with Lower Ischemia
- (2015) Jiejie Liu et al. PLoS One
- Cell Signaling and Differential Protein Expression in Neuronal Differentiation of Bone Marrow Mesenchymal Stem Cells with Hypermethylated Salvador/Warts/Hippo (SWH) Pathway Genes
- (2015) Hui-Hung Tzeng et al. PLoS One
- Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis
- (2014) Annelies Bronckaers et al. PHARMACOLOGY & THERAPEUTICS
- Mnk2 Alternative Splicing Modulates the p38-MAPK Pathway and Impacts Ras-Induced Transformation
- (2014) Avraham Maimon et al. Cell Reports
- Saturated fatty acid palmitate induces extracellular release of histone H3: A possible mechanistic basis for high-fat diet-induced inflammation and thrombosis
- (2013) Chandan Shrestha et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Overexpression of miR-126 promotes the differentiation of mesenchymal stem cells toward endothelial cells via activation of PI3K/Akt and MAPK/ERK pathways and release of paracrine factors
- (2013) Feng Huang et al. BIOLOGICAL CHEMISTRY
- Basic Fibroblast Growth Factor (bFGF) Facilitates Differentiation of Adult Dorsal Root Ganglia-Derived Neural Stem Cells Toward Schwann Cells by Binding to FGFR-1 Through MAPK/ERK Activation
- (2013) Yun Gu et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Long term effects of the implantation of Wharton^|^rsquo;s jelly-derived mesenchymal stem cells from the umbilical cord for newly-onset type 1 diabetes mellitus
- (2012) Jianxia Hu et al. ENDOCRINE JOURNAL
- Unique Responses of Stem Cell-Derived Vascular Endothelial and Mesenchymal Cells to High Levels of Glucose
- (2012) Emily Keats et al. PLoS One
- The MSC: An Injury Drugstore
- (2011) Arnold I. Caplan et al. Cell Stem Cell
- Herbal Medicines and Nutraceuticals for Diabetic Vascular Complications: Mechanisms of Action and Bioactive Phytochemicals
- (2011) Eshaifol A. Omara et al. CURRENT PHARMACEUTICAL DESIGN
- Endothelial Dysfunction in Diabetes: The role of reparatory mechanisms
- (2011) A. Avogaro et al. DIABETES CARE
- Pyridoxal 5′ phosphate protects islets against streptozotocin-induced beta-cell dysfunction – in vitro and in vivo
- (2011) Sashi G Kiran et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Identification of ApoE as an autocrine/paracrine factor that stimulates neural stem cell survival via MAPK/ERK signaling pathway
- (2011) Hui Theng Gan et al. JOURNAL OF NEUROCHEMISTRY
- Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones, dampens NSC proliferation, and maintains ventricular zone structure
- (2010) T. N. Phoenix et al. GENES & DEVELOPMENT
- VEGF autoregulates its proliferative and migratory ERK1/2 and p38 cascades by enhancing the expression of DUSP1 and DUSP5 phosphatases in endothelial cells
- (2009) Sofia Bellou et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- MAPK/ERK signalling mediates VEGF-induced bone marrow stem cell differentiation into endothelial cell
- (2008) J. Xu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Paracrine action mediate the antifibrotic effect of transplanted mesenchymal stem cells in a rat model of global heart failure
- (2008) Lili Li et al. MOLECULAR BIOLOGY REPORTS
- Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes
- (2008) William Duckworth et al. NEW ENGLAND JOURNAL OF MEDICINE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started