Thymol Alleviates LPS-Induced Liver Inflammation and Apoptosis by Inhibiting NLRP3 Inflammasome Activation and the AMPK-mTOR-Autophagy Pathway

Sodium butyrate alleviates intestinal injury and microbial flora disturbance induced by lipopolysaccharides in rats

(2022) Xiujing Dou et al.   Food & Function

Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy

(2022) Chunyan Li et al.   Frontiers in Medicine

Curcumin mitigates aflatoxin B1-induced liver injury via regulating the NLRP3 inflammasome and Nrf2 signaling pathway

(2022) Yingjie Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Sodium butyrate alleviates LPS ‐induced kidney injury via inhibiting TLR2 /4 to regulate rBD2 expression

(2022) Xiujing Dou et al.   JOURNAL OF FOOD BIOCHEMISTRY

Bacillus amyloliquefaciens B10 can alleviate liver apoptosis and oxidative stress induced by aflatoxin B1

(2021) Xiaotong Li et al.   FOOD AND CHEMICAL TOXICOLOGY

Punicalin Ameliorates Cell Pyroptosis Induced by LPS/ATP Through Suppression of ROS/NLRP3 Pathway

(2021) Ruiting Shen et al.   Journal of Inflammation Research

Thymol nanoemulsion promoted broiler chicken’s growth, gastrointestinal barrier and bacterial community and conferred protection against Salmonella Typhimurium

(2021) Doaa Ibrahim et al.   Scientific Reports

Dietary supplementation of camel whey protein attenuates heat stress-induced liver injury by inhibiting NLRP3 inflammasome activation through the HMGB1/RAGE signalling pathway

(2021) Donghua Du et al.   Journal of Functional Foods

TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation

(2021) Ying Qin et al.   Nature Communications

Ginsenoside Rb1 Reduces D-GalN/LPS-induced Acute Liver Injury by Regulating TLR4/NF-κB Signaling and NLRP3 Inflammasome

(2021) Yimei Liu et al.   Journal of Clinical and Translational Hepatology

GBP5 promotes liver injury and inflammation by inducing hepatocyte apoptosis

(2021) Kaixin Ding et al.   FASEB JOURNAL

Tryptophan Promotes Intestinal Immune Defense through Calcium-Sensing Receptor (CaSR)-Dependent Metabolic Pathways

(2021) Nan Gao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dimethyl Fumarate Alleviates NLRP3 Inflammasome Activation in Microglia and Sickness Behavior in LPS-Challenged Mice

(2021) Bora Tastan et al.   Frontiers in Immunology

Glycine Attenuates LPS-Induced Apoptosis and Inflammatory Cell Infiltration in Mouse Liver

(2020) Yunchang Zhang et al.   JOURNAL OF NUTRITION

Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway

(2020) Yuan Zhao et al.   Frontiers in Pharmacology

A potent protective effect of baicalein on liver injury by regulating mitochondria-related apoptosis

(2020) Zhongjie Yu et al.   APOPTOSIS

Macrophage Sphingosine 1-Phosphate Receptor 2 Blockade Attenuates Liver Inflammation and Fibrogenesis Triggered by NLRP3 Inflammasome

(2020) Lei Hou et al.   Frontiers in Immunology

NLRP3 is dispensable for d-galactosamine/lipopolysaccharide-induced acute liver failure

(2020) Wen Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Irisin alleviates LPS-induced liver injury and inflammation through inhibition of NLRP3 inflammasome and NF-κB signaling

(2020) Qian Li et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Shikonin Ameliorates LPS-Induced Cardiac Dysfunction by SIRT1-Dependent Inhibition of NLRP3 Inflammasome

(2020) Tao Guo et al.   Frontiers in Physiology

The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging

(2020) Paloma Gallego et al.   Cells

Autophagy alleviates mitochondrial DAMP-induced acute lung injury by inhibiting NLRP3 inflammasome

(2020) Wei Peng et al.   LIFE SCIENCES

NLRP3 inflammasome negatively regulates podocyte autophagy in diabetic nephropathy

(2019) Yun Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wogonin attenuates liver fibrosis via regulating hepatic stellate cell activation and apoptosis

(2019) Xiao-Sa Du et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Flavonoids from Livistona chinensis fruit ameliorates LPS/D-GalN-induced acute liver injury by inhibiting oxidative stress and inflammation

(2019) Meimei Wu et al.   Journal of Functional Foods

Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation

(2018) Ying Meng et al.   ANTIOXIDANTS & REDOX SIGNALING

Diterpenoid trigonoreidon B isolated from Trigonostemon reidioides alleviates inflammation in models of LPS-stimulated murine macrophages and inflammatory liver injury in mice

(2018) Tanyarath Utaipan et al.   BIOMEDICINE & PHARMACOTHERAPY

Hepatoprotective effect of α-mangostin against lipopolysaccharide/ d -galactosamine-induced acute liver failure in mice

(2018) Tianhua Fu et al.   BIOMEDICINE & PHARMACOTHERAPY

Beclin-1-Dependent Autophagy Protects the Heart During Sepsis

(2018) Yuxiao Sun et al.   CIRCULATION

Weicao capsule ameliorates renal injury through increasing autophagy and NLRP3 degradation in UAN rats

(2018) Jiacai Hu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ginsenoside 25-OCH3-PPD Promotes Activity of LXRs To Ameliorate P2X7R-Mediated NLRP3 Inflammasome in the Development of Hepatic Fibrosis

(2018) Xin Han et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Fowl adenovirus serotype 4-induced apoptosis, autophagy, and a severe inflammatory response in liver

(2018) Yujuan Niu et al.   VETERINARY MICROBIOLOGY

A Synthetic Peptide AWRK6 Alleviates Lipopolysaccharide-Induced Liver Injury

(2018) Lili Jin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway

(2018) Tianming Qiu et al.   Cell Death & Disease

NF-κB-Gasdermin D (GSDMD) Axis Couples Oxidative Stress and NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3) Inflammasome-Mediated Cardiomyocyte Pyroptosis Following Myocardial Infarction

(2018) Qian Lei et al.   MEDICAL SCIENCE MONITOR

Thymol Improves Barrier Function and Attenuates Inflammatory Responses in Porcine Intestinal Epithelial Cells during Lipopolysaccharide (LPS)-Induced Inflammation

(2018) Faith A. Omonijo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Kaempferol protects mice from d-GalN/LPS-induced acute liver failure by regulating the ER stress-Grp78-CHOP signaling pathway

(2018) Huijuan Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Metformin inhibits endothelial progenitor cell migration by decreasing matrix metalloproteinases, MMP-2 and MMP-9, via the AMPK/mTOR/autophagy pathway

(2017) Wen-Dong Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Autophagy and ER stress in LPS/GalN-induced acute liver injury

(2017) Ting Shi et al.   Molecular Medicine Reports

Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation

(2017) Jesus Cosin-Roger et al.   Nature Communications

Autophagy confers resistance to lipopolysaccharide-induced mouse hepatocyte injury

(2016) Gadi Lalazar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ghrelin protects small intestinal epithelium against sepsis-induced injury by enhancing the autophagy of intestinal epithelial cells

(2016) Sheng-Xia Wan et al.   BIOMEDICINE & PHARMACOTHERAPY

Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice

(2016) Lisanne C. Anders et al.   TOXICOLOGICAL SCIENCES