Long-term Gadolinium Retention in the Healthy Rat Brain: Comparison between Gadopiclenol, Gadobutrol, and Gadodiamide

Speciation Analysis of Gadolinium in the Water-Insoluble Rat Brain Fraction After Administration of Gadolinium-Based Contrast Agents

(2021) Izabela Strzeminska et al.   INVESTIGATIVE RADIOLOGY

Small Brain Lesion Enhancement and Gadolinium Deposition in the Rat Brain

(2021) Xavier Violas et al.   INVESTIGATIVE RADIOLOGY

Long-Term Evaluation of Gadolinium Retention in Rat Brain After Single Injection of a Clinically Relevant Dose of Gadolinium-Based Contrast Agents

(2020) Izabela Strzeminska et al.   INVESTIGATIVE RADIOLOGY

Dose Finding Study of Gadopiclenol, a New Macrocyclic Contrast Agent, in MRI of Central Nervous System

(2020) Martin Bendszus et al.   INVESTIGATIVE RADIOLOGY

Assessment of Pharmacokinetic, Pharmacodynamic Profile, and Tolerance of Gadopiclenol, A New High Relaxivity GBCA, in Healthy Subjects and Patients With Brain Lesions (Phase I/IIa Study)

(2019) Jing Hao et al.   INVESTIGATIVE RADIOLOGY

Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents

(2019) Lara Chehabeddine et al.   CRITICAL REVIEWS IN TOXICOLOGY

Physicochemical and Pharmacokinetic Profiles of Gadopiclenol

(2019) Caroline Robic et al.   INVESTIGATIVE RADIOLOGY

Gadolinium Deposition in the Brain in a Large Animal Model

(2019) Alexander Radbruch et al.   INVESTIGATIVE RADIOLOGY

Contrast-to-Dose Relationship of Gadopiclenol, an MRI Macrocyclic Gadolinium-based Contrast Agent, Compared with Gadoterate, Gadobenate, and Gadobutrol in a Rat Brain Tumor Model

(2019) Philippe Robert et al.   RADIOLOGY

Gadolinium-based contrast agents induce gadolinium deposits in cerebral vessel walls, while the neuropil is not affected: an autopsy study

(2018) Stefanie Fingerhut et al.   ACTA NEUROPATHOLOGICA

Gadolinium Retention, Brain T1 Hyperintensity, and Endogenous Metals

(2018) Marlène Rasschaert et al.   INVESTIGATIVE RADIOLOGY

Methodological Aspects for Preclinical Evaluation of Gadolinium Presence in Brain Tissue

(2018) Philippe Robert et al.   INVESTIGATIVE RADIOLOGY

One-year Retention of Gadolinium in the Brain: Comparison of Gadodiamide and Gadoterate Meglumine in a Rodent Model

(2018) Philippe Robert et al.   RADIOLOGY

LA-ICP-MS/MS improves limits of detection in elemental bioimaging of gadolinium deposition originating from MRI contrast agents in skin and brain tissues

(2018) David Clases et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Long-term Excretion of Gadolinium-based Contrast Agents: Linear versus Macrocyclic Agents in an Experimental Rat Model

(2018) Gregor Jost et al.   RADIOLOGY

Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?

(2018) Nathalie Fretellier et al.   INVESTIGATIVE RADIOLOGY

Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents

(2017) Jessica Lohrke et al.   INVESTIGATIVE RADIOLOGY

Quantification and Assessment of the Chemical Form of Residual Gadolinium in the Brain After Repeated Administration of Gadolinium-Based Contrast Agents

(2017) Thomas Frenzel et al.   INVESTIGATIVE RADIOLOGY

Differences in gadolinium retention after repeated injections of macrocyclic MR contrast agents to rats

(2017) Simona Bussi et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Gadolinium Retention in the Rat Brain: Assessment of the Amounts of Insoluble Gadolinium-containing Species and Intact Gadolinium Complexes after Repeated Administration of Gadolinium-based Contrast Agents

(2017) Eliana Gianolio et al.   RADIOLOGY

Clearance of Gadolinium from the Brain with No Pathologic Effect after Repeated Administration of Gadodiamide in Healthy Rats: An Analytical and Histologic Study

(2017) Adrian P. L. Smith et al.   RADIOLOGY

Comparison of Gadolinium Concentrations within Multiple Rat Organs after Intravenous Administration of Linear versus Macrocyclic Gadolinium Chelates

(2017) Robert J. McDonald et al.   RADIOLOGY

Gadolinium Deposition in Human Brain Tissues after Contrast-enhanced MR Imaging in Adult Patients without Intracranial Abnormalities

(2017) Robert J. McDonald et al.   RADIOLOGY

Intracranial Gadolinium Deposition Following Gadodiamide-Enhanced Magnetic Resonance Imaging in Pediatric Patients

(2017) Jennifer S. McDonald et al.   JAMA Pediatrics

Macrocyclic and Other Non–Group 1 Gadolinium Contrast Agents Deposit Low Levels of Gadolinium in Brain and Bone Tissue

(2016) Nozomu Murata et al.   INVESTIGATIVE RADIOLOGY

Gadolinium tissue deposition in brain and bone

(2016) Nozomu Murata et al.   MAGNETIC RESONANCE IMAGING

Diagnosis of Nephrogenic Systemic Fibrosis by means of Elemental Bioimaging and Speciation Analysis

(2015) Marvin Birka et al.   ANALYTICAL CHEMISTRY

Gadolinium-based Contrast Agent Accumulates in the Brain Even in Subjects without Severe Renal Dysfunction: Evaluation of Autopsy Brain Specimens with Inductively Coupled Plasma Mass Spectroscopy

(2015) Tomonori Kanda et al.   RADIOLOGY

Intracranial Gadolinium Deposition after Contrast-enhanced MR Imaging

(2015) Robert J. McDonald et al.   RADIOLOGY

High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-weighted MR Images: Relationship with Increasing Cumulative Dose of a Gadolinium-based Contrast Material

(2013) Tomonori Kanda et al.   RADIOLOGY

Comparative In Vivo Dissociation of Gadolinium Chelates in Renally Impaired Rats

(2011) Nathalie Fretellier et al.   INVESTIGATIVE RADIOLOGY

Stability of Gadolinium-Based Magnetic Resonance Imaging Contrast Agents in Human Serum at 37°C

(2010) Thomas Frenzel et al.   INVESTIGATIVE RADIOLOGY

Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions

(2008) Martin A. Sieber et al.   EUROPEAN RADIOLOGY