Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis

Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI

(2021) Chuan’ai Chen et al.   Cell Death & Disease

Lipoxin A4 Restores Septic Renal Function via Blocking Crosstalk Between Inflammation and Premature Senescence

(2021) Chaojin Chen et al.   Frontiers in Immunology

Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2

(2021) Yunwen Yang et al.   Clinical and Translational Medicine

Renoprotective Effects of Melatonin against Vancomycin-Related Acute Kidney Injury in Hospitalized Patients: a Retrospective Cohort Study

(2021) Thomas S. Hong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

VDR activation attenuate cisplatin induced AKI by inhibiting ferroptosis

(2020) Zhaoxin Hu et al.   Cell Death & Disease

Melatonin pretreatment alleviates renal ischemia-reperfusion injury by promoting autophagic flux via TLR4/MyD88/MEK/ERK/mTORC1 signaling

(2020) Jinghui Yang et al.   FASEB JOURNAL

Rutaecarpine derivative Cpd-6c alleviates acute kidney injury by targeting PDE4B, a key enzyme mediating inflammation in cisplatin nephropathy

(2020) Xue-qi Liu et al.   BIOCHEMICAL PHARMACOLOGY

XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia−reperfusion injury

(2020) Zhi Zhao et al.   Cell Death & Disease

Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury‐induced ferroptosis

(2020) Tongyu Rui et al.   JOURNAL OF PINEAL RESEARCH

Cyst Reduction by Melatonin in a Novel Drosophila Model of Polycystic Kidney Disease

(2020) Cassandra Millet-Boureima et al.   MOLECULES

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Melatonin in chronic kidney disease: a promising chronotherapy targeting the intrarenal renin–angiotensin system

(2019) Asadur Rahman et al.   HYPERTENSION RESEARCH

Hemin-induced platelet activation and ferroptosis is mediated through ROS-driven proteasomal activity and inflammasome activation: Protection by Melatonin

(2019) Somanathapura K. NaveenKumar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death

(2019) Melania Guerrero-Hue et al.   FASEB JOURNAL

Acute kidney injury

(2019) Claudio Ronco et al.   LANCET

Emerging Role of Ferroptosis in Acute Kidney Injury

(2019) Zhaoxin Hu et al.   Oxidative Medicine and Cellular Longevity

Inhibition of gap junction composed of Cx43 prevents against acute kidney injury following liver transplantation

(2019) Dongdong Yuan et al.   Cell Death & Disease

Mitochondrial Uncoupling Proteins: Subtle Regulators of Cellular Redox Signaling

(2018) Petr Ježek et al.   ANTIOXIDANTS & REDOX SIGNALING

Crosstalk between Connexin 32 and mitochondrial apoptotic signaling pathway plays a pivotal role in renal ischemia reperfusion–induced acute kidney injury

(2018) Chaojin Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

CCL20 blockade increases the severity of nephrotoxic folic acid-induced acute kidney injury

(2018) Cristian González-Guerrero et al.   JOURNAL OF PATHOLOGY

Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury

(2018) Koshu Okubo et al.   NATURE MEDICINE

Lipid storage and lipophagy regulates ferroptosis

(2018) Yuansong Bai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Immunopathogenesis of Acute Kidney Injury

(2018) Zaher A. Radi   TOXICOLOGIC PATHOLOGY

NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

(2017) Delin Chen et al.   MOLECULAR CELL

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

(2016) Diego Martin-Sanchez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis

(2016) Tanja Krainz et al.   ACS Central Science

Role of progesterone in melatonin-mediated protection against acute kidney injury

(2014) Jyotsna Sehajpal et al.   JOURNAL OF SURGICAL RESEARCH

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury

(2013) Abolfazl Zarjou et al.   JOURNAL OF CLINICAL INVESTIGATION

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The role of melatonin treatment in chronic kidney disease

(2012) Marije Russcher   Frontiers in Bioscience-Landmark

The xc− cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance

(2008) M Lo et al.   BRITISH JOURNAL OF CANCER