Disturbance of Fatty Acid Metabolism Promoted Vascular Endothelial Cell Senescence via Acetyl-CoA-Induced Protein Acetylation Modification

Short Chain Fatty Acids Outpace Ketone Oxidation in the Failing Heart

(2021) Andrew N. Carley et al.   CIRCULATION

Glycolysis is integral to histamine‐induced endothelial hyperpermeability

(2021) Athanasios Ziogas et al.   FASEB JOURNAL

The role of short-chain fatty acids in intestinal barrier function, inflammation, oxidative stress, and colonic carcinogenesis

(2021) Pinyi Liu et al.   PHARMACOLOGICAL RESEARCH

Acetyl-CoA Metabolism and Histone Acetylation in the Regulation of Aging and Lifespan

(2021) Patrick C. Bradshaw   Antioxidants

Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence

(2021) Momoko Ohori et al.   BMC GENOMICS

CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells

(2020) Seonhee Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Aging alters acetylation status in skeletal and cardiac muscles

(2020) Dongwook Yeo et al.   GeroScience

Histone methyltransferase Smyd3 is a new regulator for vascular senescence

(2020) Di Yang et al.   AGING CELL

Rhamnocitrin extracted from Nervilia fordii inhibited vascular endothelial activation via miR-185/STIM-1/SOCE/NFATc3

(2020) Tong Lin et al.   PHYTOMEDICINE

The Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

(2019) Hendrik Bartolomaeus et al.   CIRCULATION

Fra-1 plays a critical role in angiotensin II–induced vascular senescence

(2019) Di Yang et al.   FASEB JOURNAL

Metabolic Pathways Fueling the Endothelial Cell Drive

(2019) Xuri Li et al.   Annual Review of Physiology

Intestinal Microbiota in Cardiovascular Health and Disease

(2019) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

An allosteric mechanism for potent inhibition of human ATP-citrate lyase

(2019) Jia Wei et al.   NATURE

Gut Microbiota and Fecal Levels of Short-Chain Fatty Acids Differ Upon 24-Hour Blood Pressure Levels in Men

(2019) Justine Huart et al.   HYPERTENSION

PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension

(2019) Yapeng Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Metabolic Basis for Endothelial-to-Mesenchymal Transition

(2018) Jianhua Xiong et al.   MOLECULAR CELL

Endothelial Cell Metabolism

(2018) Guy Eelen et al.   PHYSIOLOGICAL REVIEWS

Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling

(2018) Wenwei Luo et al.   Aging-US

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

(2018) Joanna Kalucka et al.   Cell Metabolism

Mechanisms of Vascular Aging

(2018) Zoltan Ungvari et al.   CIRCULATION RESEARCH

PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis

(2018) Qiuhua Yang et al.   Nature Communications

Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory

(2017) Philipp Mews et al.   NATURE

NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation

(2017) Suvi M Kuosmanen et al.   NUCLEIC ACIDS RESEARCH

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease

(2017) Laura Bierhansl et al.   PHYSIOLOGY

Carnitine transport and fatty acid oxidation

(2016) Nicola Longo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Memory CD8 + T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function

(2016) Maria L. Balmer et al.   IMMUNITY

Endothelial cells: source, barrier, and target of defensive mediators

(2016) Lubka T. Roumenina et al.   IMMUNOLOGICAL REVIEWS

Short- and medium-chain fatty acids in energy metabolism: the cellular perspective

(2016) Peter Schönfeld et al.   JOURNAL OF LIPID RESEARCH

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

(2015) Sandra Schoors et al.   NATURE

Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation

(2014) Joyce V. Lee et al.   Cell Metabolism

Mitochondrial protein acetylation regulates metabolism

(2014) Kristin A. Anderson et al.   Essays in Biochemistry

Mitochondrial protein acetylation is driven by acetyl-CoA from fatty acid oxidation

(2014) Olga Pougovkina et al.   HUMAN MOLECULAR GENETICS

Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A

(2014) Guillermo Mariño et al.   MOLECULAR CELL

Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione

(2013) Dan Nguyen et al.   AGING CELL

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

Endothelial Fatty Acid Transport: Role of Vascular Endothelial Growth Factor B

(2013) Carolina Hagberg et al.   PHYSIOLOGY

SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence

(2012) Anna Cardus et al.   CARDIOVASCULAR RESEARCH

SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aortic Endothelial Cells

(2010) Yi Zu et al.   CIRCULATION RESEARCH

Vascular endothelial growth factor B controls endothelial fatty acid uptake

(2010) Carolina E. Hagberg et al.   NATURE

Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells

(2009) Harun Elmasri et al.   FASEB JOURNAL

Dietary saturated and unsaturated fats as determinants of blood pressure and vascular function

(2009) Wendy L. Hall   NUTRITION RESEARCH REVIEWS

Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking

(2008) Angel Sandoval et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Vascular endothelial senescence: from mechanisms to pathophysiology

(2008) Jorge D. Erusalimsky   JOURNAL OF APPLIED PHYSIOLOGY