SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

Sirtuins at a glance

(2011) T. Nakagawa et al.   JOURNAL OF CELL SCIENCE

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

(2011) Virginia Guarani et al.   NATURE

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

(2011) Z. Mao et al.   SCIENCE

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aortic Endothelial Cells

(2010) Yi Zu et al.   CIRCULATION RESEARCH

Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction

(2010) M. AHLUWALIA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

SIRT6 protects against pathological damage caused by diet-induced obesity

(2009) Yariv Kanfi et al.   AGING CELL

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Vascular endothelial senescence: from mechanisms to pathophysiology

(2008) Jorge D. Erusalimsky   JOURNAL OF APPLIED PHYSIOLOGY

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

(2008) Eriko Michishita et al.   NATURE