One step closer to linking GWAS SNPs with the right genes

Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease

(2022) Seyhan Yazar et al.   SCIENCE

Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus

(2022) Richard K. Perez et al.   SCIENCE

Multiple causal variants underlie genetic associations in humans

(2022) Nathan S. Abell et al.   SCIENCE

Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity

(2022) Steven Gazal et al.   NATURE GENETICS

Genome-wide enhancer maps link risk variants to disease genes

(2021) Joseph Nasser et al.   NATURE

Exome sequencing and analysis of 454,787 UK Biobank participants

(2021) Joshua D. Backman et al.   NATURE

An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci

(2021) Edward Mountjoy et al.   NATURE GENETICS

Functionally informed fine-mapping and polygenic localization of complex trait heritability

(2020) Omer Weissbrod et al.   NATURE GENETICS

Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model

(2018) Naomi R. Wray et al.   CELL

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

(2013) D. E. Bauer et al.   SCIENCE

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE