Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus
出版年份 2022 全文链接
标题
Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus
作者
关键词
-
出版物
SCIENCE
Volume 376, Issue 6589, Pages -
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2022-04-08
DOI
10.1126/science.abf1970
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Author Correction: ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis
- (2021) Jeffrey M. Granja et al. NATURE GENETICS
- Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus
- (2020) Yuri Kotliarov et al. NATURE MEDICINE
- SciPy 1.0: fundamental algorithms for scientific computing in Python
- (2020) Pauli Virtanen et al. NATURE METHODS
- Role of GSDMB in Pyroptosis and Cancer
- (2020) Lisha Li et al. Cancer Management and Research
- Generalizing RNA velocity to transient cell states through dynamical modeling
- (2020) Volker Bergen et al. NATURE BIOTECHNOLOGY
- Mapping systemic lupus erythematosus heterogeneity at the single-cell level
- (2020) Djamel Nehar-Belaid et al. NATURE IMMUNOLOGY
- Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data
- (2019) Samuel L. Wolock et al. Cell Systems
- Ormdl3 and Allergic Asthma: from Physiology to Pathology
- (2019) Briana James et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Landscape of stimulation-responsive chromatin across diverse human immune cells
- (2019) Diego Calderon et al. NATURE GENETICS
- 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus
- (2019) Martin Aringer et al. Arthritis & Rheumatology
- Trial of Anifrolumab in Active Systemic Lupus Erythematosus
- (2019) Eric F. Morand et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Bayesian framework for multiple trait colocalization from summary association statistics
- (2018) Claudia Giambartolomei et al. BIOINFORMATICS
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
- (2018) Hilary K. Finucane et al. NATURE GENETICS
- Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR
- (2018) David Zemmour et al. NATURE IMMUNOLOGY
- Genetic contributions to lupus nephritis in a multi-ethnic cohort of systemic lupus erythematous patients
- (2018) Cristina M. Lanata et al. PLoS One
- Causal associations between risk factors and common diseases inferred from GWAS summary data
- (2018) Zhihong Zhu et al. Nature Communications
- RNA velocity of single cells
- (2018) Gioele La Manno et al. NATURE
- The ORMDL3 Asthma Gene Regulates ICAM1 and has Multiple Effects on Cellular Inflammation
- (2018) Youming Zhang et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection
- (2018) Chun Jimmie Ye et al. GENOME RESEARCH
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α–Endoplasmic Reticulum Stress–Beclin1 Autophagy Regulatory Pathway
- (2017) Jie Dang et al. JOURNAL OF IMMUNOLOGY
- Multiplexed droplet single-cell RNA-sequencing using natural genetic variation
- (2017) Hyun Min Kang et al. NATURE BIOTECHNOLOGY
- Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors
- (2017) Alexandra-Chloé Villani et al. SCIENCE
- Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective
- (2017) Vaishali R. Moulton et al. TRENDS IN MOLECULAR MEDICINE
- Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients
- (2016) Romain Banchereau et al. CELL
- Next-generation genotype imputation service and methods
- (2016) Sayantan Das et al. NATURE GENETICS
- The global burden of SLE: prevalence, health disparities and socioeconomic impact
- (2016) Erin E. Carter et al. Nature Reviews Rheumatology
- 17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells
- (2016) Benjamin Joachim Schmiedel et al. Nature Communications
- Systemic lupus erythematosus
- (2016) Arvind Kaul et al. Nature Reviews Disease Primers
- Widely divergent transcriptional patterns between SLE patients of different ancestral backgrounds in sorted immune cell populations
- (2015) Shruti Sharma et al. JOURNAL OF AUTOIMMUNITY
- Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity
- (2015) Kira Rubtsova et al. JOURNAL OF IMMUNOLOGY
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
- (2015) James Bentham et al. NATURE GENETICS
- Interindividual variation in human T regulatory cells
- (2014) A. Ferraro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intersection of population variation and autoimmunity genetics in human T cell activation
- (2014) C. J. Ye et al. SCIENCE
- Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes
- (2014) T. Raj et al. SCIENCE
- Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells
- (2014) M. N. Lee et al. SCIENCE
- Statistical Testing of Shared Genetic Control for Potentially Related Traits
- (2013) Chris Wallace GENETIC EPIDEMIOLOGY
- Matrix eQTL: ultra fast eQTL analysis via large matrix operations
- (2012) A. A. Shabalin BIOINFORMATICS
- DNase I sensitivity QTLs are a major determinant of human expression variation
- (2012) Jacob F. Degner et al. NATURE
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
- (2012) Jian Yang et al. NATURE GENETICS
- Integrating Autoimmune Risk Loci with Gene-Expression Data Identifies Specific Pathogenic Immune Cell Subsets
- (2011) Xinli Hu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies
- (2011) Buhm Han et al. AMERICAN JOURNAL OF HUMAN GENETICS
- GCTA: A Tool for Genome-wide Complex Trait Analysis
- (2010) Jian Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- LocusZoom: regional visualization of genome-wide association scan results
- (2010) R. J. Pruim et al. BIOINFORMATICS
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- The role of B cells in lupus pathogenesis
- (2009) Emil Nashi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
- (2009) Jeffrey C Barrett et al. NATURE GENETICS
- ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
- (2009) J. Chen et al. NUCLEIC ACIDS RESEARCH
- Age‐ and sex‐related patterns of serum interferon‐α activity in lupus families
- (2008) Timothy B. Niewold et al. ARTHRITIS AND RHEUMATISM
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation