Adipose tissue thermogenesis by calcium futile cycling

Creatine kinase B controls futile creatine cycling in thermogenic fat

(2021) Janane F. Rahbani et al.   NATURE

Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis

(2020) Kazuki Tajima et al.   Nature Communications

CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling

(2020) Yasuo Oguri et al.   CELL

UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes

(2020) Kenji Ikeda et al.   Frontiers in Endocrinology

Identification of Metabolically Distinct Adipocyte Progenitor Cells in Human Adipose Tissues

(2019) Arthe Raajendiran et al.   Cell Reports

12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

(2019) Luiz Osório Leiria et al.   Cell Metabolism

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

(2019) Takeshi Yoneshiro et al.   NATURE

Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells

(2019) So Yun Min et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular heterogeneity in brown adipose tissue

(2019) Yasuo Oguri et al.   JOURNAL OF CLINICAL INVESTIGATION

Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis

(2018) Yutaka Hasegawa et al.   Cell Metabolism

The Common and Distinct Features of Brown and Beige Adipocytes

(2018) Kenji Ikeda et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Developmental and functional heterogeneity of white adipocytes within a single fat depot

(2018) Kevin Y Lee et al.   EMBO JOURNAL

Thermal stress induces glycolytic beige fat formation via a myogenic state

(2018) Yong Chen et al.   NATURE

UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis

(2017) Kenji Ikeda et al.   NATURE MEDICINE

Mapping of human brown adipose tissue in lean and obese young men

(2017) Brooks P. Leitner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

(2016) Jonathan Z. Long et al.   CELL

A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function

(2016) Katrin J. Svensson et al.   Cell Metabolism

A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

(2015) Lawrence Kazak et al.   CELL

Brown and Beige Fat: Physiological Roles beyond Heat Generation

(2015) Shingo Kajimura et al.   Cell Metabolism

Exercise Effects on White Adipose Tissue: Beiging and Metabolic Adaptations

(2015) Kristin I. Stanford et al.   DIABETES

Genetic and functional characterization of clonally derived adult human brown adipocytes

(2015) Kosaku Shinoda et al.   NATURE MEDICINE

Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus

(2015) Mark J W Hanssen et al.   NATURE MEDICINE

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

(2014) Paul Cohen et al.   CELL

A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia

(2014) Michele Petruzzelli et al.   Cell Metabolism

Temperature-Acclimated Brown Adipose Tissue Modulates Insulin Sensitivity in Humans

(2014) Paul Lee et al.   DIABETES

Taking control over intracellular fatty acid levels is essential for the analysis of thermogenic function in cultured primary brown and brite/beige adipocytes

(2014) Y. Li et al.   EMBO REPORTS

The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis

(2014) Guo-Xiao Wang et al.   NATURE MEDICINE

Recruited brown adipose tissue as an antiobesity agent in humans

(2013) Takeshi Yoneshiro et al.   JOURNAL OF CLINICAL INVESTIGATION

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

(2013) Anouk A.J.J. van der Lans et al.   JOURNAL OF CLINICAL INVESTIGATION

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex

(2013) Haruya Ohno et al.   NATURE

Evidence for two types of brown adipose tissue in humans

(2013) Martin E Lidell et al.   NATURE MEDICINE

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

(2013) Aaron M Cypess et al.   NATURE MEDICINE

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals

(2012) Naresh C Bal et al.   NATURE MEDICINE

Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells

(2012) Louis Z. Sharp et al.   PLoS One

Chronic cold acclimation increases thermogenic capacity, non-shivering thermogenesis and muscle citrate synthase activity in both wild-type and brown adipose tissue deficient mice

(2011) P.M. Mineo et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice

(2010) Carola W. Meyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cold tolerance of UCP1-ablated mice: A skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects

(2010) Irina G. Shabalina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Mice lacking brain-type creatine kinase activity show defective thermoregulation

(2009) Femke Streijger et al.   PHYSIOLOGY & BEHAVIOR

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform

(2007) Tatiana V. Kramarova et al.   FASEB JOURNAL