Early developmental electroencephalography abnormalities, neonatal seizures, and induced spasms in a mouse model of tuberous sclerosis complex

Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex

(2019) Bo Zhang et al.   NEUROBIOLOGY OF DISEASE

Utilizing Animal Models of Infantile Spasms

(2018) Chris G. Dulla   Epilepsy Currents

Longitudinal analysis of developmental changes in electroencephalography patterns and sleep-wake states of the neonatal mouse

(2018) Nicholas Rensing et al.   PLoS One

Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner

(2017) Jia Zou et al.   EPILEPSIA

Predictors of Drug-Resistant Epilepsy in Tuberous Sclerosis Complex

(2017) Anna Jeong et al.   JOURNAL OF CHILD NEUROLOGY

APC conditional knock-out mouse is a model of infantile spasms with elevated neuronal β-catenin levels, neonatal spasms, and chronic seizures

(2017) Antonella Pirone et al.   NEUROBIOLOGY OF DISEASE

Epilepsy in youngTsc1+/−mice exhibits age-dependent expression that mimics that of human tuberous sclerosis complex

(2016) Svetlana Gataullina et al.   EPILEPSIA

Microglial activation during epileptogenesis in a mouse model of tuberous sclerosis complex

(2016) Bo Zhang et al.   EPILEPSIA

Genetic animal models of malformations of cortical development and epilepsy

(2016) Michael Wong et al.   JOURNAL OF NEUROSCIENCE METHODS

Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study

(2016) Jacqueline A French et al.   LANCET

Convulsive seizures from experimental focal cortical dysplasia occur independently of cell misplacement

(2016) Lawrence S. Hsieh et al.   Nature Communications

Development of a mouse model of infantile spasms induced by N -methyl- d -aspartate

(2015) Xiu-Yu Shi et al.   EPILEPSY RESEARCH

Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex

(2015) Bo Zhang et al.   NEUROBIOLOGY OF DISEASE

Tuberous Sclerosis Complex

(2015) Francis J. DiMario et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model

(2014) N. Lozovaya et al.   Nature Communications

Everolimus treatment of refractory epilepsy in tuberous sclerosis complex

(2013) Darcy A. Krueger et al.   ANNALS OF NEUROLOGY

Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex

(2013) Bo Zhang et al.   PLoS One

Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions

(2011) Laura Magri et al.   Cell Stem Cell

Validation of the rat model of cryptogenic infantile spasms

(2011) Tamar Chachua et al.   EPILEPSIA

Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice

(2011) David M. Feliciano et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex

(2011) J. Goto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SLEEP DISORDER AND EPILEPSY IN CHILDREN WITH TUBEROUS SCLEROSIS: A QUESTIONNAIRE-BASED STUDY

(2010) Ann Hunt et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of Tuberous Sclerosis Complex

(2010) L.-H. Zeng et al.   HUMAN MOLECULAR GENETICS

Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex

(2010) Ling-Hui Zeng et al.   NEUROBIOLOGY OF DISEASE

The tuberous sclerosis complex

(2009) Ksenia A. Orlova et al.   Annals of the New York Academy of Sciences

The natural history of epilepsy in tuberous sclerosis complex

(2009) Catherine J. Chu-Shore et al.   EPILEPSIA

Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex

(2009) Lin Xu et al.   NEUROBIOLOGY OF DISEASE

A model of symptomatic infantile spasms syndrome

(2009) Morris H. Scantlebury et al.   NEUROBIOLOGY OF DISEASE

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex

(2008) Ling-Hui Zeng et al.   ANNALS OF NEUROLOGY

Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function

(2008) L. Meikle et al.   JOURNAL OF NEUROSCIENCE