Piezo channels contribute to the regulation of myelination in Schwann cells

Therapeutic Low-Intensity Ultrasound for Peripheral Nerve Regeneration – A Schwann Cell Perspective

(2022) Jenica Acheta et al.   Frontiers in Cellular Neuroscience

The Hippo pathway: Horizons for innovative treatments of peripheral nerve diseases

(2021) M. Laura Feltri et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Piezo1 impairs hepatocellular tumor growth via deregulation of the MAPK-mediated YAP signaling pathway

(2021) Silin Liu et al.   CELL CALCIUM

Calcineurin Activity Is Increased in Charcot-Marie-Tooth 1B Demyelinating Neuropathy

(2021) Mariapaola Sidoli et al.   JOURNAL OF NEUROSCIENCE

Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration

(2021) Bing Chen et al.   Frontiers in Cellular Neuroscience

Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT)

(2021) Daniel Gerber et al.   eLife

Piezo2 mechanosensitive ion channel is located to sensory neurons and nonneuronal cells in rat peripheral sensory pathway

(2021) Seung Min Shin et al.   PAIN

Piezo 1 activation facilitates cholangiocarcinoma metastasis via Hippo/YAP signaling axis

(2021) Biqiang Zhu et al.   Molecular Therapy-Nucleic Acids

Mechanotransduction assays for neural regeneration strategies: A focus on glial cells

(2021) Nicolas Marinval et al.   APL Bioengineering

Targeting Mechanosensitive Piezo1 Alleviated Renal Fibrosis Through p38MAPK-YAP Pathway

(2021) Yuanyuan Fu et al.   Frontiers in Cell and Developmental Biology

Mechanical stretch induces myelin protein loss in oligodendrocytes by activating Erk1/2 in a calcium‐dependent manner

(2020) Jihyun Kim et al.   GLIA

Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity

(2020) Jolien Wolbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin

(2020) Taifeng Zhou et al.   eLife

Inhibition of transient receptor potential melastatin 7 (TRPM7) protects against Schwann cell trans-dedifferentiation and proliferation during Wallerian degeneration

(2020) Young Hwa Kim et al.   Animal Cells and Systems

YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation

(2020) Kana Hasegawa et al.   JOURNAL OF PATHOLOGY

Cyclic tensile stimulation enrichment of Schwann cell-laden auxetic hydrogel scaffolds towards peripheral nerve tissue engineering

(2020) Yi-Wen Chen et al.   MATERIALS & DESIGN

YAP and TAZ regulate Schwann cell proliferation and differentiation during peripheral nerve regeneration

(2020) Haley Jeanette et al.   GLIA

Increased TRPV4 expression in non-myelinating Schwann cells is associated with demyelination after sciatic nerve injury

(2020) Xiaona Feng et al.   Communications Biology

Mutations in C1orf194, encoding a calcium regulator, cause dominant Charcot-Marie-Tooth disease

(2019) Shun-Chang Sun et al.   BRAIN

Peripheral myelin protein 22 modulates store operated calcium channel activity, providing insights into Charcot-Marie-Tooth disease etiology

(2019) Carlos G. Vanoye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-guided examination of the mechanogating mechanism of PIEZO2

(2019) Francisco J. Taberner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Niche stiffness underlies the ageing of central nervous system progenitor cells

(2019) Michael Segel et al.   NATURE

Inhibition of Piezo1 attenuates demyelination in the central nervous system

(2019) María Velasco‐Estevez et al.   GLIA

Corrigendum: YAP and TAZ Regulate Cc2d1b and Purβ in Schwann Cells

(2019) Sophie Belin et al.   Frontiers in Molecular Neuroscience

A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies

(2018) Yannick Poitelon et al.   JOURNAL OF NEUROCHEMISTRY

Myelinating Schwann Cell Polarity and Mechanically-Driven Myelin Sheath Elongation

(2018) Nicolas Tricaud   Frontiers in Cellular Neuroscience

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

(2018) Jerome J. Lacroix et al.   Nature Communications

Activity-induced Ca2+ signaling in perisynaptic Schwann cells of the early postnatal mouse is mediated by P2Y1 receptors and regulates muscle fatigue

(2018) Dante J Heredia et al.   eLife

Cellular Mechanotransduction: From Tension to Function

(2018) Fabiana Martino et al.   Frontiers in Physiology

Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy

(2018) Sophie Belin et al.   HUMAN MOLECULAR GENETICS

Ca2+ activity signatures of myelin sheath formation and growth in vivo

(2017) Marion Baraban et al.   NATURE NEUROSCIENCE

Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo

(2017) Anna M. Krasnow et al.   NATURE NEUROSCIENCE

Influence of Mechanical Stimuli on Schwann Cell Biology

(2017) Sophie Belin et al.   Frontiers in Cellular Neuroscience

A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination

(2017) Yaqi Deng et al.   Nature Communications

Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice

(2017) Francesco De Logu et al.   Nature Communications

Cell-Type-Specific Splicing of Piezo2 Regulates Mechanotransduction

(2017) Marcin Szczot et al.   Cell Reports

YAP/TAZ initiate and maintain Schwann cell myelination

(2017) Matthew Grove et al.   eLife

The molecular physiology of the axo-myelinic synapse

(2016) Ileana Micu et al.   EXPERIMENTAL NEUROLOGY

Tead1 regulates the expression ofPeripheral Myelin Protein 22during Schwann cell development

(2016) Camila Lopez-Anido et al.   HUMAN MOLECULAR GENETICS

YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells

(2016) Yannick Poitelon et al.   NATURE NEUROSCIENCE

Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway

(2016) Ruani N. Fernando et al.   Nature Communications

Myelinating glia differentiation is regulated by extracellular matrix elasticity

(2016) Mateusz M. Urbanski et al.   Scientific Reports

Neuronal Regulation of Schwann Cell Mitochondrial Ca2+ Signaling during Myelination

(2015) Daisuke Ino et al.   Cell Reports

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination

(2014) M. E. Sheean et al.   GENES & DEVELOPMENT

Piezo Proteins: Regulators of Mechanosensation and Other Cellular Processes

(2014) Sviatoslav N. Bagriantsev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three-dimensional traction forces of Schwann cells on compliant substrates

(2014) C. Lopez-Fagundo et al.   Journal of the Royal Society Interface

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

(2014) Medha M. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sustained Activation of ERK1/2 MAPK in Oligodendrocytes and Schwann Cells Enhances Myelin Growth and Stimulates Oligodendrocyte Progenitor Expansion

(2013) A. Ishii et al.   JOURNAL OF NEUROSCIENCE

The influence of substrate stiffness on the behavior and functions of Schwann cells in culture

(2012) Yun Gu et al.   BIOMATERIALS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Behavioral and Molecular Exploration of the AR-CMT2A Mouse Model Lmna R298C/R298C

(2012) Yannick Poitelon et al.   NEUROMOLECULAR MEDICINE

The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4

(2011) Chilman Bae et al.   BIOCHEMISTRY

Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves

(2011) Bartomeu Colom et al.   FASEB JOURNAL

Specific Functions for ERK/MAPK Signaling during PNS Development

(2011) Jason M. Newbern et al.   NEURON

Control of Local Protein Synthesis and Initial Events in Myelination by Action Potentials

(2011) H. Wake et al.   SCIENCE

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

An In-Vitro Traumatic Model To Evaluate the Response of Myelinated Cultures to Sustained Hydrostatic Compression Injury

(2009) Laura R. Frieboes et al.   JOURNAL OF NEUROTRAUMA

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

(2009) Guida Landouré et al.   NATURE GENETICS