Suppression of angiotensin II-activated NOX4/NADPH oxidase and mitochondrial dysfunction by preserving glucagon-like peptide-1 attenuates myocardial fibrosis and hypertension
出版年份 2022 全文链接
标题
Suppression of angiotensin II-activated NOX4/NADPH oxidase and mitochondrial dysfunction by preserving glucagon-like peptide-1 attenuates myocardial fibrosis and hypertension
作者
关键词
-
出版物
EUROPEAN JOURNAL OF PHARMACOLOGY
Volume 927, Issue -, Pages 175048
出版商
Elsevier BV
发表日期
2022-05-26
DOI
10.1016/j.ejphar.2022.175048
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Integrating Measures of Myocardial Fibrosis in the Transition from Hypertensive Heart Disease to Heart Failure
- (2021) R. Brandon Stacey et al. CURRENT HYPERTENSION REPORTS
- Cardiac Fibrosis: Key Role of Integrins in Cardiac Homeostasis and Remodeling
- (2021) Patrick B. Meagher et al. Cells
- Bnip3 in mitophagy: novel insights and potential therapeutic target for diseases of secondary mitochondrial dysfunction
- (2020) Anbo Gao et al. CLINICA CHIMICA ACTA
- DPP (Dipeptidyl Peptidase)-4 Inhibitor Attenuates Ang II (Angiotensin II)–Induced Cardiac Hypertrophy via GLP (Glucagon-Like Peptide)-1–Dependent Suppression of Nox (Nicotinamide Adenine Dinucleotide Phosphate Oxidase) 4-HDAC (Histone Deacetylase) 4 Pathway
- (2020) Kosuke Okabe et al. HYPERTENSION
- Exogenous supplement of glucagon like peptide-1 protects the heart against aortic banding induced myocardial fibrosis and dysfunction through inhibiting mTOR/p70S6K signaling and promoting autophagy
- (2020) Rong-Hua Zheng et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Pharmacological blockage of ICAM-1 improves angiotensin II-induced cardiac remodeling by inhibiting adhesion of LFA-1+ monocytes
- (2019) Qiu-Yue Lin et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension
- (2019) Johanna Helmstädter et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress
- (2019) Anna E. Dikalova et al. CIRCULATION RESEARCH
- A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4
- (2018) Takehiro Yamaguchi et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM
- (2018) Pankaj Bagul et al. Cells
- Ellagic acid antagonizes Bnip3-mediated mitochondrial injury and necrotic cell death of cardiac myocytes
- (2017) Abhinav Dhingra et al. FREE RADICAL BIOLOGY AND MEDICINE
- The Biological Basis for Cardiac Repair After Myocardial Infarction
- (2016) Sumanth D. Prabhu et al. CIRCULATION RESEARCH
- Angiotensin II-Induced Early and Late Inflammatory Responses Through NOXs and MAPK Pathways
- (2016) Xi Zhang et al. INFLAMMATION
- Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling
- (2016) Shouji Matsushima et al. JOURNAL OF CLINICAL INVESTIGATION
- Angiotensin II AT1 receptor alters ACE2 activity, eNOS expression and CD44-hyaluronan interaction in rats with hypertension and myocardial fibrosis
- (2016) Feng Bai et al. LIFE SCIENCES
- Prenatal hypoxia enhanced angiotensin II-mediated vasoconstriction via increased oxidative signaling in fetal rats
- (2016) Xiaolin Zhu et al. REPRODUCTIVE TOXICOLOGY
- Preservation of Glucagon-Like Peptide-1 Level Attenuates Angiotensin II-Induced Tissue Fibrosis by Altering AT1/AT2 Receptor Expression and Angiotensin-Converting Enzyme 2 Activity in Rat Heart
- (2015) Li-Hui Zhang et al. CARDIOVASCULAR DRUGS AND THERAPY
- NADPH Oxidase 4 Induces Cardiac Fibrosis and Hypertrophy Through Activating Akt/mTOR and NF B Signaling Pathways
- (2015) Q. D. Zhao et al. CIRCULATION
- Circulating miR-21 and eNOS in subclinical atherosclerosis in patients with hypertension
- (2015) Mahir Cengiz et al. CLINICAL AND EXPERIMENTAL HYPERTENSION
- Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis
- (2015) Tracey Gaspari et al. Diabetes & Vascular Disease Research
- Dipeptidyl peptidase-4 inhibitor improves cardiac function by attenuating adverse cardiac remodelling in rats with chronic myocardial infarction
- (2015) Tharnwimol Inthachai et al. EXPERIMENTAL PHYSIOLOGY
- Angiotensin II receptor blocker irbesartan attenuates cardiac dysfunction induced by myocardial infarction in the presence of renal failure
- (2015) Ryo Watanabe et al. HYPERTENSION RESEARCH
- Angiotensin Ⅱ Activates MCP-1 and Induces Cardiac Hypertrophy and Dysfunction via Toll-like Receptor 4
- (2015) Susumu Matsuda et al. Journal of Atherosclerosis and Thrombosis
- The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4
- (2015) Naveen K. Somanna et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Monocyte and Macrophage Heterogeneity in the Heart
- (2013) Matthias Nahrendorf et al. CIRCULATION RESEARCH
- NADPH Oxidases in Heart Failure: Poachers or Gamekeepers?
- (2012) Min Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
- Vascular Nox4
- (2012) Rhian M. Touyz et al. CIRCULATION RESEARCH
- SIRT3 regulation of mitochondrial oxidative stress
- (2012) Alexandra S. Bause et al. EXPERIMENTAL GERONTOLOGY
- Endothelial NADPH oxidases: friends or foes?
- (2011) Henning Morawietz BASIC RESEARCH IN CARDIOLOGY
- NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation
- (2011) Siobhan M. Craige et al. CIRCULATION
- β2-Adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another ‘radical’ road to heart failure?
- (2010) Fabio Di Lisa et al. BRITISH JOURNAL OF PHARMACOLOGY
- Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes
- (2010) Tetsuro Ago et al. CIRCULATION RESEARCH
- NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis
- (2010) M. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart
- (2010) J. Kuroda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism
- (2009) Melissa N. Quinsay et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Metallothionein Suppresses Angiotensin II–Induced Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation, Nitrosative Stress, Apoptosis, and Pathological Remodeling in the Diabetic Heart
- (2008) Guihua Zhou et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction
- (2007) Abdulrahman K. Doughan et al. CIRCULATION RESEARCH
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