Novel Smooth Muscle Ca 2+ -Signaling Nanodomains in Blood Pressure Regulation

Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice

(2021) Zdravka Daneva et al.   eLife

Local Peroxynitrite Impairs Endothelial TRPV4 Channels and Elevates Blood Pressure in Obesity

(2020) Matteo Ottolini et al.   CIRCULATION

Mechanisms underlying selective coupling of endothelial Ca 2+ signals with eNOS versus IK/SK channels in systemic and pulmonary arteries

(2020) Matteo Ottolini et al.   JOURNAL OF PHYSIOLOGY-LONDON

Shear stress induces pathological changes in endothelial cells through Piezo1 activation of TRPV4

(2020) Sandip M. Swain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myogenic vasoconstriction requires G12/G13 and LARG to maintain local and systemic vascular resistance

(2019) Ramesh Chennupati et al.   eLife

TRPV4 (Transient Receptor Potential Vanilloid 4) Channel–Dependent Negative Feedback Mechanism Regulates GqProtein–Coupled Receptor–Induced VasoconstrictionHighlights

(2018) Kwangseok Hong et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure

(2018) Leon J. DeLalio et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular smooth muscle contraction in hypertension

(2018) Rhian M Touyz et al.   CARDIOVASCULAR RESEARCH

Caveolae Link Ca V 3.2 Channels to BK Ca -Mediated Feedback in Vascular Smooth Muscle

(2018) Ahmed M. Hashad et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells

(2018) Osama F Harraz et al.   eLife

Genetic compensation: A phenomenon in search of mechanisms

(2017) Mohamed A. El-Brolosy et al.   PLoS Genetics

TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction

(2015) Neil M. Goldenberg et al.   ANESTHESIOLOGY

Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in MiceSignificance

(2015) Jie Hong Hu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Opposing roles of smooth muscle BK channels and ryanodine receptors in the regulation of nerve-evoked constriction of mesenteric resistance arteries

(2014) Gayathri Krishnamoorthy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Stretch–Activation of Angiotensin II Type 1 a Receptors Contributes to the Myogenic Response of Mouse Mesenteric and Renal Arteries

(2014) Johanna Schleifenbaum et al.   CIRCULATION RESEARCH

The Autonomic Nervous System and Hypertension

(2014) Giuseppe Mancia et al.   CIRCULATION RESEARCH

Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle

(2014) Jose Mercado et al.   JOURNAL OF GENERAL PHYSIOLOGY

AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension

(2014) S. K. Sonkusare et al.   Science Signaling

A PLC 1-Dependent, Force-Sensitive Signaling Network in the Myogenic Constriction of Cerebral Arteries

(2014) A. L. Gonzales et al.   Science Signaling

TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension

(2013) Yang Xia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The role of myogenic mechanisms in human cerebrovascular regulation

(2013) Can Ozan Tan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli

(2013) Anna Garcia-Elias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses

(2013) K. M. Dunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging role of G protein-coupled receptors in microvascular myogenic tone

(2012) G. Kauffenstein et al.   CARDIOVASCULAR RESEARCH

Transcriptional Upregulation of α 2 δ-1 Elevates Arterial Smooth Muscle Cell Voltage-Dependent Ca 2+ Channel Surface Expression and Cerebrovascular Constriction in Genetic Hypertension

(2012) John P. Bannister et al.   HYPERTENSION

The β3 Subunit Contributes to Vascular Calcium Channel Upregulation and Hypertension in Angiotensin II–Infused C57BL/6 Mice

(2012) Sujay V. Kharade et al.   HYPERTENSION

Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function

(2012) S. K. Sonkusare et al.   SCIENCE

The sympathetic nervous system and blood pressure in humans: implications for hypertension

(2011) J P Fisher et al.   JOURNAL OF HUMAN HYPERTENSION

Sympathetic Nervous System and Blood Pressure in Humans

(2010) Michael J. Joyner et al.   HYPERTENSION

AKAP150 Is Required for Stuttering Persistent Ca 2+ Sparklets and Angiotensin II–Induced Hypertension

(2008) Manuel F. Navedo et al.   CIRCULATION RESEARCH

Modulation of the myogenic response by neurogenic influences in rat small arteries

(2005) Stephanie Anschütz et al.   BRITISH JOURNAL OF PHARMACOLOGY