Article
Chemistry, Applied
Tao Ma, Ranran Cui, Shuyu Lu, Xinna Hu, Bo Xu, Yi Song, Xiaosong Hu
Summary: This study explored the utilization of highly concentrated oil-in-water emulsions to create edible 3D materials, successfully developing a high internal phase Pickering emulsion with excellent stability and printability. The research demonstrated the ability to 3D print high-resolution, high-fidelity shapes under specific conditions.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Multidisciplinary
Seyed Mohammad Amin Ojagh, Majed Amini, Sierra Cranmer-Smith, Farzaneh Vahabzadeh, Mohammad Arjmand, Kam C. Tam, Orlando J. Rojas, Milad Kamkar, Theo G. M. van de Ven
Summary: This study addresses two challenges in additive manufacturing of cellulosic hydrogels and cryogels: inadequate rheological properties of ENCC suspensions for 3D printing of hydrogels and poor mechanical properties of 3D printed CNC cryogels. These limitations are effectively overcome by hybridization of CNC/ENCC at an optimized weight ratio. Controlling the CNC/ENCC ratio allows for high tunability of rheological properties, enabling high-fidelity printing of 3D hydrogels, and mechanical performance of cryogels can be tailored by manipulating the CNC/ENCC ratio. Compared to neat CNC cryogels, CNC/ENCC (1:1) cryogels have 78% higher compressive strength. This research opens new opportunities for sustainable, biocompatible, and lightweight cellulosic structured scaffolds with a wide range of applications.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Physical
Yannick Nagel, Deeptanshu Sivaraman, Antonia Neels, Tanja Zimmermann, Shanyu Zhao, Gilberto Siqueira, Gustav Nystrom
Summary: This study presents a simple and versatile method for fabricating cellulose aerogels with controlled shape and thermal-mechanical properties using 3D printing technique. The printed aerogels exhibit higher thermal-mechanical properties compared to traditional manufacturing processes. This method allows customized structures for load-bearing insulating materials in thermal management.
Article
Engineering, Electrical & Electronic
Pablo A. Mercadal, Marcelo R. Romero, Maria del Mar Montesinos, Juan Pablo Real, Matias L. Picchio, Agustin Gonzalez
Summary: By using tannic acid-decorated cellulose nanocrystals (TA@CNC), we have successfully improved the mechanical properties and ionic conductivity of biocompatible eutectogels made of gelatin and a eutectic mixture composed of choline chloride and ethylene glycol (ethaline). This enhancement makes eutectogels a promising material for bioelectronics.
ACS APPLIED ELECTRONIC MATERIALS
(2023)
Article
Engineering, Biomedical
Jone Uranga, Teresa Carranza, Miriam Penalba, Koro de la Caba, Pedro Guerrero
Summary: Cellulose-containing residue from agar production was used as a filler in soy protein-based hydrogels for 3D printing without further purification. The addition of cellulose led to morphological changes and improved hardness and shape recovery of the 3D-printed products. The physicochemical characterization revealed high swelling capacity and integrity of the 3D-printed products in wet conditions, indicating their potential for circular economy and efficient resource utilization.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Chemistry, Multidisciplinary
Luca A. E. Mueller, Anita Zingg, Andrea Arcifa, Tanja Zimmermann, Gustav Nystroem, Ingo Burgert, Gilberto Siqueira
Summary: This study introduces a new manufacturing method that combines the reinforcement effects of CNC with photoinduced responses, allowing the fabrication of self-standing 3D structures with locally shear-induced alignment of nanoparticles that soften reversibly under visible light irradiation. These novel materials not only exhibit shape memory behavior but also enable dynamic mechanical responses.
Article
Engineering, Chemical
Connor D. Armstrong, Liang Yue, Yulin Deng, Jerry Qi
Summary: Edible 3D printing using customized nutrition and visual appeal is achieved through the use of cellulose nanocrystals as a rheological modifier, enabling the printing of various foodstuffs such as spinach puree, tomato puree, and applesauce. This study demonstrates the effectiveness of cellulose nanocrystals in promoting shear-thinning behavior, necessary for the DIW 3D printing of self-supporting edible structures.
JOURNAL OF FOOD ENGINEERING
(2022)
Article
Nanoscience & Nanotechnology
Luca A. E. Mueller, Adrien Demongeot, Joanne Vaucher, Yves Leterrier, Jonathan Avaro, Marianne Liebi, Antonia Neels, Ingo Burgert, Tanja Zimmermann, Gustav Nystroem, Gilberto Siqueira
Summary: Photoresponsive soft liquid crystalline elastomers can be 3D printed to achieve precise control, making them promising candidates for soft robotic or muscle-like devices. This study introduces biocompatible cellulose nanocrystals into the material, enabling photomechanical behavior and precise tailoring of mechanical properties.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Engineering, Electrical & Electronic
Pablo A. Mercadal, Marcelo R. Romero, Maria del Mar Montesinos, Juan Pablo Real, Matias L. Picchio, Agustin Gonzalez
Summary: Tannic acid-decorated cellulose nanocrystals (TA@CNC) are used as dynamic nanofillers to improve the mechanical and ionic conductivity properties of biocompatible eutectogels.
ACS APPLIED ELECTRONIC MATERIALS
(2023)
Review
Engineering, Manufacturing
Ashish Kalkal, Sumit Kumar, Pramod Kumar, Rangadhar Pradhan, Magnus Willander, Gopinath Packirisamy, Saurabh Kumar, Bansi Dhar Malhotra
Summary: Three-dimensional (3D) printing technologies are driving the development of wearable (bio)sensors with exciting characteristics such as high stretchability, super flexibility, low cost, ultra-thinness, and lightweight. This advanced manufacturing technology has revolutionized the concept of free form construction and end-user customization, leading to the fabrication of smaller, faster, and more efficient wearable devices. The contribution of 3D printing in developing novel structures for wearable applications using printable soft and functional materials is highlighted, along with the summary of major printing techniques and various (bio)sensing platforms discussed in terms of design specifications and fabrication strategies.
ADDITIVE MANUFACTURING
(2021)
Article
Chemistry, Applied
Cynthia Hopson, Victoria Rigual, M. Virginia Alonso, Mercedes Oliet, Francisco Rodriguez
Summary: 3D printing is a promising technology for fabricating cost-effective and customizable objects. Research on bio-based inks with recyclable and eco-friendly properties is increasing due to the need to substitute fossil fuels as raw materials. In this study, ionogels and hydrogels were formulated for 3D printing using cellulose dissolved in [Emim] [DMP] at different concentrations. Rheological properties and printability were compared with a commercial ink, and the 4 wt% ink was found to have the best print resolution and fidelity. These 3D printed cellulose ionogels and hydrogels may have applications in the electrochemical and medical fields, respectively.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Mohsen Esmaeili, Sepideh Norouzi, Kyle George, Gelareh Rezvan, Nader Taheri-Qazvini, Monirosadat Sadati
Summary: Inspired by natural Bouligand structures, researchers have successfully used cellulose nanocrystals (CNC)-based inks for 3D printing to create structures with guided long-range radial twisted chirality. The nanostructures during the printing process were evaluated using rheological measurements, in situ flow analysis, polarized optical microscopy (POM), and director field analysis. By incorporating a photo-curable monomer, the chirality of the printed filaments was locked, and optimized Carbopol microgels were used to support the as-printed inks before photo-polymerization. This biomimetic approach opens up new possibilities for developing bio-inspired materials with nanoscale hierarchies in larger-scale 3D printed constructs.
Review
Biochemistry & Molecular Biology
Aref Abbasi Moud, Aliyeh Abbasi Moud
Summary: Cellulosic sources can be degraded to produce cellulose nanocrystals (CNCs), which have various applications in biomedicine, photonics, and material engineering due to their biodegradability, renewability, sustainability, and mechanical qualities. The rheological behavior of CNC suspension or in combination with other chemicals is crucial for the processing and design of CNC-based products. This review article provides new research on the shear rheology of CNC dispersion and CNC-based hydrogels, as well as their applications in technology and material science.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Materials Science, Paper & Wood
Aref Abbasi Moud, Milad Kamkar, Amir Sanati-Nezhad, Seyed Hossein Hejazi
Summary: This article reviews the microstructural characterization of cellulose nanocrystal (CNC)-based suspensions and hydrogels using imaging and rheological approaches, and introduces new applications of CNC suspensions and gels. Fine-tuning the properties of CNC colloids using existing methods and models is crucial due to the significant potential of CNC-based products in various fields.
Article
Chemistry, Physical
Yuxin Chen, Zhirong Deng, Ri Ouyang, Renhao Zheng, Zhiqiang Jiang, Hua Bai, Hao Xue
Summary: A newly developed 3D printing method allows for the preparation of stretchable elastic fibers with a coaxial core-sheath structure, providing good conductivity and insulation properties suitable for smart textiles. Large-scale customized manufacturing of stretchable smart textiles is now achievable.
Article
Materials Science, Multidisciplinary
Vitaly K. Vorobiov, Michael A. Smirnov, Natalya Bobrova, Maria P. Sokolova
Summary: The study focuses on a solid polymer electrolyte based on choline chloride/lactic acid deep eutectic solvent encapsulated in a chitosan matrix, showing high ionic conductivity and wide electrochemical stability window, suitable for electrochemical energy storage devices. Additionally, film electrodes prepared on this matrix exhibit high specific capacitance for assembling supercapacitors.
Article
Materials Science, Characterization & Testing
Michael A. Smirnov, Alexandra L. Nikolaeva, Natalia Bobrova, Vitaly K. Vorobiov, Alexander Smirnov, Erkki Lahderanta, Maria P. Sokolova
Summary: Plasticized chitosan films with high content of NADES based on citric acid and choline chloride were prepared, showing self-healing ability and maximal mechanical characteristics. The formation of hydrogen bond network in the films was observed, suggesting its role in self-healing capabilities. Structure, morphology, and thermal properties of the prepared films were discussed.
Article
Polymer Science
Michael A. Smirnov, Veronika S. Fedotova, Maria P. Sokolova, Alexandra L. Nikolaeva, Vladimir Yu Elokhovsky, Mikko Karttunen
Summary: A novel approach for 3D-printing BC reinforced UV-curable ion gels using two-component solvents has been demonstrated in this study. The cholinium-based systems showed lower viscosity and improved stability compared to the imidazolium-based ones. The grafting of poly(acrylic acid) onto cellulose nanofibers resulted in higher elongation at break and enhanced mechanical properties for choline chloride-based compositions.
Article
Polymer Science
Elizaveta V. Batishcheva, Darya N. Sokolova, Veronika S. Fedotova, Maria P. Sokolova, Alexandra L. Nikolaeva, Alexey Y. Vakulyuk, Christina Y. Shakhbazova, Mauro Carlos Costa Ribeiro, Mikko Karttunen, Michael A. Smirnov
Summary: This study demonstrates the preparation route of cellulose nanofiber dispersions from bacterial cellulose using ethylene glycol- or glycerol-based deep eutectic solvents (DES). The combined influence of DES treatment and ultrasound on the thermal and mechanical properties of bacterial cellulose nanofibers (BC-NFs) is investigated. The results show that the maximal Young's modulus is achieved with ethylene glycol-based DES and ultrasound treatment, while the maximal strength is achieved with glycerol-based DES and ultrasound treatment. The improved mechanical and thermal characteristics are attributed to the disordering of the BC-NF surface structure and the preservation of high crystallinity bulk.
Article
Polymer Science
Denis Andzheevich Sapegin, Galina Nikolaevna Gubanova, Elena Nikolaevna Vlasova, Natalya Vladimirovna Zaharova, Nadezhda Vasil'evna Afanas'eva, Elena Nikolaevna Popova, Maria Petrovna Sokolova, Viktor Konstantinovich Lavrentyev, Oleg Nikolaevich Primachenko, Svetlana Viktorovna Kononova
Summary: This study investigates the prospective strategy of introducing blocks inclined to form areas of high crystallinity into sulfonated block co-polyimide to enhance swelling resistance and dimensional stability. The obtained copolymer with a highly crystalline block is characterized and its transport properties are evaluated. The results show that the introduction of a high-crystalline block can lead to a stable proton conductivity in a wide range of temperature and relative humidity values.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Alexandra L. Nikolaeva, Alexander N. Bugrov, Maria P. Sokolova, Elena M. Ivan'kova, Ivan Abalov, Elena N. Vlasova, Iosif Gofman
Summary: By studying the fabrication and characterization of polyimide/metal oxide nanocomposite films, we have identified trends in the functional properties of these materials based on factors such as the type, size, concentration of the nanofiller, and the chemical structure of the matrix polyimide.
Article
Materials Science, Multidisciplinary
Angelina P. Prosvirnina, Alexander N. Bugrov, Anatoliy Dobrodumov, Elena N. Vlasova, Veronika S. Fedotova, Alexandra L. Nikolaeva, Vitaly K. Vorobiov, Maria P. Sokolova, Michael A. Smirnov
Summary: This study functionalized cellulose nanofibers produced by bacteria and utilized them as a crosslinker and reinforcer for the preparation of polymerizable deep eutectic solvent. The results showed that the functionalization improved the quality of 3D printed materials and significantly increased their strength and elongation compared to unmodified nanofibers.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Polymer Science
Veronika S. S. Fedotova, Maria P. P. Sokolova, Vitaliy K. K. Vorobiov, Eugene V. V. Sivtsov, Mauro C. C. Ribeiro, Michael A. A. Smirnov
Summary: Two polymerizable ionic liquids were synthesized and their chemical structure and thermal properties were analyzed. One of the ionic liquids demonstrated the potential to dissolve bacterial cellulose and showed promising applications in 3D printing ink.
Article
Polymer Science
Serafim Rodchenko, Mikhail Kurlykin, Andrey Tenkovtsev, Sergey Milenin, Maria Sokolova, Alexander Yakimansky, Alexander Filippov
Summary: Regular and irregular molecular brushes with polydimethylsiloxane backbone and poly-2-isopropyl-2-oxazoline side chains were synthesized and their properties and behavior in aqueous solutions were studied. It was found that the molecular shape of the brushes was not affected by regularity and grafting density, but the grafting density played a crucial role in determining the thermoresponsivity.
Article
Polymer Science
Alexandra L. L. Nikolaeva, Alexander N. N. Bugrov, Maria P. P. Sokolova, Igor V. V. Kuntsman, Elena N. N. Vlasova, Elena M. M. Ivan'kova, Ivan V. V. Abalov, Iosif V. V. Gofman
Summary: This paper reports on novel polyimide (PI) nanocomposites filled with binary mixtures of metal oxide nanoparticles and nanocarbon materials. The structure, morphology, thermal, and mechanical properties of the materials were comprehensively studied. The synergistic effect of the nanoconstituents on various functional characteristics of the PIs was revealed, and the possibility of manipulating the material properties by choosing the proper combination of nanofillers was demonstrated. This research provides a platform for the design of PI-based engineering materials with tailored characteristics for extreme conditions.
Article
Polymer Science
Veronika S. Fedotova, Maria P. Sokolova, Vitaly K. Vorobiov, Eugene V. Sivtsov, Natalia V. Lukasheva, Michael A. Smirnov
Summary: This study aimed to investigate the influence of water as a co-solvent on the interaction between a polymerizable ionic liquid and bacterial cellulose. It was found that the addition of water reduces the viscosity and yield stress of the solvent, and decreases the stability of dispersion under stress. The optimal composition of ChA/water was determined to ensure printability and stability of the ink.
Article
Polymer Science
Angelina P. Prosvirnina, Alexander N. Bugrov, Natalya V. Bobrova, Eugene V. Sivtsov, Alexandra L. Nikolaeva, Almaz M. Kamalov, Maria P. Sokolova, Michael A. Smirnov
Summary: Inks for 3D printing were prepared by dispersing methacrylate-functionalized bacterial cellulose nanofibers (CNF) in a polymerizable deep eutectic solvent (DES) with water as a cosolvent. The resulting 3D-printed gels were composed of chemically and physically crosslinked networks formed from modified CNF and polymerized DES, respectively. The addition of water improved the mechanical properties of the composite gel, while an anhydrous system exhibited better shape memory properties.
Review
Polymer Science
M. A. Smirnov, D. A. Tolmachev, A. D. Glova, M. P. Sokolova, P. V. Geydt, N. V. Lukasheva, S. V. Lyulin
Summary: Publications analyzing the combination of computer simulation and atomic force microscopy for studying polymer biological objects and materials for various purposes are discussed, highlighting the main directions in which the two techniques are used together.
POLYMER SCIENCE SERIES C
(2021)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
